全文获取类型
收费全文 | 8626篇 |
免费 | 532篇 |
国内免费 | 50篇 |
专业分类
耳鼻咽喉 | 261篇 |
儿科学 | 576篇 |
妇产科学 | 350篇 |
基础医学 | 550篇 |
口腔科学 | 467篇 |
临床医学 | 870篇 |
内科学 | 1919篇 |
皮肤病学 | 154篇 |
神经病学 | 562篇 |
特种医学 | 383篇 |
外科学 | 1808篇 |
综合类 | 114篇 |
预防医学 | 226篇 |
眼科学 | 331篇 |
药学 | 371篇 |
中国医学 | 9篇 |
肿瘤学 | 257篇 |
出版年
2024年 | 13篇 |
2023年 | 134篇 |
2022年 | 91篇 |
2021年 | 218篇 |
2020年 | 169篇 |
2019年 | 251篇 |
2018年 | 327篇 |
2017年 | 256篇 |
2016年 | 365篇 |
2015年 | 375篇 |
2014年 | 441篇 |
2013年 | 671篇 |
2012年 | 549篇 |
2011年 | 496篇 |
2010年 | 392篇 |
2009年 | 300篇 |
2008年 | 549篇 |
2007年 | 561篇 |
2006年 | 590篇 |
2005年 | 540篇 |
2004年 | 383篇 |
2003年 | 322篇 |
2002年 | 267篇 |
2001年 | 174篇 |
2000年 | 168篇 |
1999年 | 158篇 |
1998年 | 81篇 |
1997年 | 78篇 |
1996年 | 66篇 |
1995年 | 40篇 |
1994年 | 32篇 |
1993年 | 33篇 |
1992年 | 21篇 |
1991年 | 30篇 |
1990年 | 16篇 |
1989年 | 7篇 |
1988年 | 7篇 |
1987年 | 3篇 |
1984年 | 4篇 |
1982年 | 3篇 |
1980年 | 2篇 |
1978年 | 3篇 |
1977年 | 2篇 |
1974年 | 2篇 |
1971年 | 3篇 |
1970年 | 2篇 |
1962年 | 1篇 |
1960年 | 1篇 |
1947年 | 1篇 |
1935年 | 1篇 |
排序方式: 共有9208条查询结果,搜索用时 15 毫秒
1.
2.
3.
Targeting in a cellular level is still one of the major challenges in biomedical treatments. However, new synthetic and analytical techniques now allow the development of precisely prepared macromolecules. Thus, glycopolymer chains are reported to be prepared with controlled length, monomer sequences, as well as chain‐folded structures. A high level of complexity in synthetic macromolecules also allows increased selectivity in targeting, which is a key factor in biomedical applications. 相似文献
4.
Comparison of local and general anesthesia in tension-free (Lichtenstein) hernioplasty: a prospective randomized trial 总被引:3,自引:0,他引:3
To compare pulmonary effects, postoperative pain and fatigue, morbidity, patient satisfaction, and cost of different anesthetic
techniques for inguinal hernia repair, 50 patients were randomized to local and general anesthesia groups (LA and GA). All
patients received the same premedications and the same postoperative analgesic regimen. The standardized postoperative analgesic,
intramuscular pyroxicam 20 mg, was given to all patients in the recovery room and an additional 20 mg on the same day was
given as requested by each patient. Pulmonary function studies and arterial blood gas analysis were performed 1 h prior to
the operation and at the postoperative 8th and 24th hours. All patients underwent Lichtenstein's tension-free hernioplasty.
Postoperative pain and fatigue were registered 8 h and 24 h after the operation. A questionnaire was filled out by the patients,
and they were asked to give grades for the general comfort of the anesthesia and the surgical procedure (1=worst, 10=best).
Postoperative pulmonary function tests were significantly poorer in the GA group both on 8th- and 24th-hour measurements (P<0.05). Patients who underwent LA had significantly lower PCO2 and higher PO2 at the postoperative 8th hour (P<0.05). Mean postoperative pain and fatigue scores revealed a significant difference in favor of local anesthesia at only
the 8th hour (P<0.05). There were two complications, one in each group (a hematoma in LA and a urinary retention in GA). Patient satisfaction
grades were not different in the two groups. We conclude that LA in inguinal hernia repair does not adversely affect pulmonary
functions, patients feel less pain, and patient satisfaction is comparable to that with GA.
Electronic Publication 相似文献
5.
6.
Formulation and in Vitro-in Vivo Evaluation of Sustained-Release Lithium Carbonate Tablets 总被引:1,自引:0,他引:1
Çiftçi Kadriye Çapan Yilmaz Öztürk Orhan Hincal A. Atilla 《Pharmaceutical research》1990,7(4):359-363
The release of lithium carbonate incorporated into polymethylmethacrylate, poly vinyl chloride, hy-drogenated vegetable oil, and carbomer matrix tablets was studied in vitro. The formulation containing 10% carbomer showed a sustained-release profile comparable to that of a standard, commercially available, sustained-release preparation containing 400 mg lithium carbonate embedded in a composite material. In vivo the newly formulated and standard sustained-release lithium carbonate tablets were compared to an oral solution and conventional lithium carbonate tablets in 12 healthy subjects. These crossover studies showed that the sustained-release tablets produced a flatter serum concentration curve than the oral solution and conventional tablet, without loss of total bioavailability. 相似文献
7.
8.
9.
Z Yilmaz T Renton Y Yiangou J Zakrzewska I P Chessell C Bountra P Anand 《Journal of clinical neuroscience》2007,14(9):864-871
Burning mouth syndrome (BMS) is often an idiopathic chronic and intractable pain condition, affecting 1.5-5.5% of middle-aged and elderly women. We have studied the heat and capsaicin receptor TRPV1, and its regulator nerve growth factor (NGF), in BMS. Patients with BMS (n=10) and controls (n=10) were assessed for baseline and post-topical capsaicin pain scores, and their tongue biopsies immunostained for TRPV1, NGF, and structural nerve markers neurofilament and peripherin. Nerve fibres penetrating the epithelium were less abundant in BMS (p<0.0001), indicating a small fibre neuropathy. TRPV1-positive fibres were overall significantly increased in BMS (p=0.0011), as were NGF fibres (p<0.0001) and basal epithelial cell NGF staining (p<0.0147). There was a significant correlation between the baseline pain score and TRPV1 (p=0.0143) and NGF fibres (p=0.0252). A significant correlation was observed between baseline and post-capsaicin pain (p=0.0006). Selective TRPV1 and NGF blockers may provide a new therapy for BMS. 相似文献
10.