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排序方式: 共有102条查询结果,搜索用时 31 毫秒
1.
Sema Büğüşan Aysu Kahraman Bülent Elbasan Akmer Mutlu 《Disability and health journal》2018,11(2):287-292
Background
It is important to determine the quality of life (QoL) and level of participation in children with Cerebral Palsy (CP). Previous research has used reports from adolescents or caregivers, but there is no evidence that caregivers' reports accurately reflect the experiences of the adolescents they are interested in.Objective/Hypothesis
The aim of this study was to investigate whether a difference was present in the views of the adolescents and their caregivers regarding the participation and the quality of life of adolescents with CP, and to reveal the parameters creating such differences.Methods
The participation levels and QoL of the adolescents were evaluated separately by the caregiver and the adolescent using the Pediatric Outcomes Data Collection Instrument (PODCI).Results
A statistically significant difference was found in terms of caregivers and adolescents' scores of PODCI upper extremity (Z = ?2,560, p = 0,008), transfer&basic mobility (Z = ?3,839, p = 0,000), sports/physical functioning (Z = ?3,103, p = 0,002), happiness (Z = ?2,420, p = 0,016) and global functioning (Z = ?3,639, p = 0,001). The children's scores were statistically significantly higher than caregivers'. It was found that there was a poor consistence in terms of caregivers and adolescents' scores of upper extremity (ICC = 0,373, p = 0,012), transfer/basic mobility (ICC = 0,289, p = 0,016), sport/physical functioning (ICC = 0,359, p = 0,009); moderate consistence in terms of those of global functioning (ICC = 0,421, p = 0,003).Conclusion
It was determined that caregivers and children's answers were not compatible with one another especially in terms of subjective assessments such as happiness and pain, which suggests that the consideration of caregivers or children in the assessment of subjective situations will change the results. 相似文献2.
Ayda Turkoz Aysu Kocum H. Evren Eker Hacer Ulgen Mustafa Uysalel Gulnaz Arslan 《Journal of anesthesia》2010,24(1):43-48
Purpose
We investigated whether inserting an intrathecal catheter and leaving it in place for 24 h after an unintentional dural puncture in orthopedic patients reduced the incidence of post-dural puncture headache (PDPH).Methods
The study consisted of 427 patients in whom a total of 21 unintentional dural punctures had occurred during orthopedic surgery performed between 2002 and 2006. Seven patients (phase I; evaluated retrospectively) each underwent placement of an epidural catheter at another level after dural puncture during the period January 2002 to February 2004. Fourteen patients (phase II; evaluated prospectively) received an epidural catheter through the dural tear after an unintentional dural puncture during the period February 2004–March 2006Results
In phase I, 5 of the 7 patients experienced PDPH, and one required an epidural blood patch. In phase II, only one of the 14 patients complained of PDPH, which resolved after 48 h of medical therapy. No patient experienced paresthesia, neurologic or hemorrhagic complication, or infection.Conclusion
Inserting an epidural catheter through the dural tear following an unintentional dural puncture and leaving it in place for 24 h significantly reduces the incidence of PDPH. 相似文献3.
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Neslihan Üstündağ-Okur Aysu Yurdasiper Evren Gündoğdu 《Journal of microencapsulation》2016,33(1):30-42
Nebivolol (NB)-loaded solid lipid nanoparticles (SLNs) were prepared and modified with chitosan oligosaccharide lactate (COL) and polyethylene glycol (PEG) stearate for improvement of its oral bioavailability. Compritol, poloxamer and lecithin were used for the preparation of SLNs by homogenisation method. After in vitro characterisation effect of lipase, pepsin, or pancreatin on degradation and release rate were investigated. Cytotoxicity and permeation were studied on Caco-2 cells. As COL concentration increased in SLNs, size and zeta potential increased. PEG concentration was reversely proportional to particle size with no change in zeta potential. Encapsulation efficiencies (EEs) were determined as 84–98%. DSC confirmed solubilisation of NB in lipid matrix. A sustained release with no burst effect was determined. The presence of enzymes affected the release. SLNs did not reveal cytotoxicity and highest permeability was obtained with PEG modification. PEG-modified SLNs could be offered as a promising strategy for oral delivery of NB. 相似文献
9.
Tunc VT Camurdan AD Ilhan MN Sahin F Beyazova U 《European journal of pediatrics》2008,167(12):1357-1362
To identify the normal defecation patterns and the factors affecting these patterns in the first two years of life, a questionnaire
was given to the parents of 1,021 children who were followed in a well-child clinic. The time of first meconium passage, presence
of colic symptoms, frequency, color, and consistency of stools were recorded.Mann Whitney U, Wilcoxon, chi-square, and correlation
tests were used in the statistical analyses. The median number of defecations per day was six in the first month of life.
This decreased to once in the second month and almost all cases remained so until the end of the 24th month. At the second
month of age, 39.3% of infants passed stools less than once a day. This pattern of rare defecation was seen until the end
of 6 months, when supplemental foods were started. Stool frequency was higher in exclusively breast-fed infants (p = 0.0001). Infants who had colic symptoms in the first 2 months had less frequent defecation during the first 2 years of
life (p = 0.0001). In addition to confirming the previously observed defecation patterns of 0–2-year-old infants, this study provides
the relationship between colic symptoms and stool frequency, and showed that the second month of life was unique in the sense
that the frequency of stooling decreased to half of the previous month and 39.3% of these infants defecated less than once
a day. 相似文献
10.
Ozgur Akbay?r Aytul Corbac?oglu Esmer Ceyhun Numanoglu B. Pinar C?les?z Goksedef Aysu Akca Lale Vuslat Bak?r Oguzhan Kuru 《Archives of gynecology and obstetrics》2012,286(5):1269-1276