全文获取类型
收费全文 | 5078篇 |
免费 | 500篇 |
国内免费 | 31篇 |
专业分类
耳鼻咽喉 | 25篇 |
儿科学 | 154篇 |
妇产科学 | 149篇 |
基础医学 | 637篇 |
口腔科学 | 209篇 |
临床医学 | 630篇 |
内科学 | 1009篇 |
皮肤病学 | 43篇 |
神经病学 | 306篇 |
特种医学 | 176篇 |
外科学 | 765篇 |
综合类 | 117篇 |
现状与发展 | 1篇 |
一般理论 | 1篇 |
预防医学 | 444篇 |
眼科学 | 143篇 |
药学 | 432篇 |
中国医学 | 36篇 |
肿瘤学 | 332篇 |
出版年
2023年 | 35篇 |
2022年 | 80篇 |
2021年 | 165篇 |
2020年 | 101篇 |
2019年 | 126篇 |
2018年 | 142篇 |
2017年 | 104篇 |
2016年 | 97篇 |
2015年 | 141篇 |
2014年 | 194篇 |
2013年 | 262篇 |
2012年 | 272篇 |
2011年 | 316篇 |
2010年 | 200篇 |
2009年 | 157篇 |
2008年 | 259篇 |
2007年 | 250篇 |
2006年 | 278篇 |
2005年 | 215篇 |
2004年 | 206篇 |
2003年 | 169篇 |
2002年 | 185篇 |
2001年 | 134篇 |
2000年 | 111篇 |
1999年 | 91篇 |
1998年 | 46篇 |
1997年 | 31篇 |
1996年 | 26篇 |
1995年 | 26篇 |
1992年 | 54篇 |
1991年 | 69篇 |
1990年 | 46篇 |
1989年 | 52篇 |
1988年 | 51篇 |
1987年 | 48篇 |
1986年 | 46篇 |
1985年 | 41篇 |
1984年 | 57篇 |
1983年 | 44篇 |
1982年 | 41篇 |
1981年 | 36篇 |
1980年 | 42篇 |
1979年 | 43篇 |
1978年 | 37篇 |
1977年 | 38篇 |
1976年 | 26篇 |
1974年 | 42篇 |
1973年 | 32篇 |
1972年 | 30篇 |
1971年 | 32篇 |
排序方式: 共有5609条查询结果,搜索用时 15 毫秒
1.
Daniel Schar Pawin Padungtod Nguyen Tung Michael OLeary Wantanee Kalpravidh Filip Claes 《Influenza and other respiratory viruses》2019,13(6):618-621
Among the chief limitations in achieving early detection and control of animal‐origin influenza of pandemic potential in high‐risk livestock populations is the existing lag time between sample collection and diagnostic result. Advances in molecular diagnostics are permitting deployment of affordable, rapid, highly sensitive, and specific point‐of‐capture assays, providing opportunities for targeted surveillance driving containment strategies with potentially compelling returns on investment. Interrupting disease transmission at source holds promise of disrupting cycles of animal‐origin influenza incursion to endemicity and limiting impact on animal production, food security, and public health. Adoption of new point‐of‐capture diagnostics should be undertaken in the context of promoting robust veterinary services systems and parallel support for operationalizing pre‐authorized plans and communication strategies that will ensure that the full potential of these new platforms is realized. 相似文献
2.
3.
Andrea Stracciolini Jennifer Luz Gregory Walker Nicholas M. Edwards Avery D. Faigenbaum Gregory D. Myer 《The Physician and sportsmedicine》2020,48(2):199-207
ABSTRACT
Objective
To investigate primary care physician clinical practice patterns, barriers, and education surrounding pediatric physical activity (PA), and to compare practice patterns by discipline. 相似文献4.
5.
A case illustrating the potentially fatal complication of endogenous Gram Negative Aerobic Bacillus (GNAB) septicaemia secondary to nosocomial pneumonia is presented along with current theories as to its aetiology. The technique of selective decontamination of the digestive tract is designed and advocated to prevent such occurrences; oral and maxillofacial surgeons should be aware of this approach. It may be, however, that by using much simpler manoeuvres such as changes in policy regarding gastric stress ulcer prophylaxis, the already small risk of such an occurrence will be further reduced. Awareness of this condition will allow a higher index of suspicion when presented with catastrophic septic complications on the ITU and aid in more rational planning of antimicrobial therapy. 相似文献
6.
We compared the effects of alpha 2- and beta-adrenoreceptor blockade on the central actions of catecholamines and metabolites of alpha-methyldihydroxyphenylalanine, epinephrine, alpha-methylnorepinephrine, and alpha-methylepinephrine were studied. I.c.v. and nucleus tractus solitarii (NTS) injections were carried out under anesthesia. Following i.c.v. injection, both epinephrine and methylepinephrine rapidly reduced blood pressure and heart rate, but the effects of methylnorepinephrine occurred somewhat later. Following microinjection into the nucleus of the solitary tract, epinephrine, methylepinephrine, and methylnorepinephrine all caused hypotension and bradycardia. The hypotensive effects of all 3 amines in the NTS were attenuated in additive fashion by yohimbine, an alpha 2 adrenoreceptor antagonist, and timolol, a beta-adrenoreceptor antagonist, whereas only yohimbine attenuated the bradycardia. The combination of yohimbine and timolol abolished the effects of the amines. These data suggest that in the NTS both alpha 2 and beta adrenoreceptor stimulation contribute to the hypotensive effects of these amines, but that only alpha 2 adrenoreceptors are principally involved in the heart rate response. 相似文献
7.
Therapy of human cervical carcinoma with monoclonal antibody-Pseudomonas exotoxin conjugates. 总被引:1,自引:0,他引:1
Pseudomonas exotoxin A (PE) linked to the F(ab')2 fragment of 1H10, a murine monoclonal antibody recognizing a carbohydrate epitope of a glycoconjugate expressed on the surface of human cervical carcinoma tumor cells, was evaluated for in vitro and in vivo activity. PE can kill cells by ADP-ribosylating elongation factor 2 thus inhibiting protein synthesis. Disulfide- as well as thioether-linked immunotoxins (1H10-PE) killed cervical carcinoma cells in vitro and were 20-160 times more inhibitory to target than to control cells. Cell killing was antibody mediated as demonstrated by the reduction of 1H10-PE growth inhibition to target CaSki cells by free 1H10 F(ab')2. In addition, a control antibody immunotoxin was nontoxic to CaSki cells. Thioether-linked 1H10-PE administered either i.v. or i.p. suppressed the growth of established solid s.c. cervical carcinoma tumors xenografted in nude mice for over 30 days. Treatment with antibody alone or a control immunotoxin had no significant effect on tumor growth. Administration of immunotoxin i.p. was associated with less toxicity than administration i.v., but i.v. injections were more effective at suppressing the growth of established solid tumors. 相似文献
8.
Background
Cerebral arterial gas embolism is a potentially life-threatening event. Intraarterial air can occlude blood flow directly or cause thrombosis. Sclerotherapy is an extremely rare cause of cerebral arterial gas embolism. 相似文献9.
10.