全文获取类型
收费全文 | 246篇 |
免费 | 21篇 |
国内免费 | 6篇 |
专业分类
儿科学 | 24篇 |
基础医学 | 20篇 |
口腔科学 | 3篇 |
临床医学 | 32篇 |
内科学 | 65篇 |
皮肤病学 | 2篇 |
神经病学 | 6篇 |
特种医学 | 16篇 |
外科学 | 59篇 |
综合类 | 2篇 |
预防医学 | 12篇 |
眼科学 | 3篇 |
药学 | 14篇 |
肿瘤学 | 15篇 |
出版年
2024年 | 1篇 |
2021年 | 7篇 |
2020年 | 5篇 |
2019年 | 3篇 |
2018年 | 8篇 |
2017年 | 6篇 |
2016年 | 7篇 |
2015年 | 6篇 |
2014年 | 14篇 |
2013年 | 15篇 |
2012年 | 1篇 |
2011年 | 4篇 |
2010年 | 10篇 |
2009年 | 6篇 |
2008年 | 14篇 |
2007年 | 7篇 |
2006年 | 14篇 |
2005年 | 9篇 |
2004年 | 10篇 |
2003年 | 5篇 |
2002年 | 2篇 |
2001年 | 5篇 |
2000年 | 12篇 |
1999年 | 6篇 |
1998年 | 11篇 |
1997年 | 6篇 |
1996年 | 15篇 |
1995年 | 5篇 |
1994年 | 2篇 |
1993年 | 11篇 |
1992年 | 4篇 |
1991年 | 3篇 |
1990年 | 2篇 |
1989年 | 6篇 |
1988年 | 2篇 |
1987年 | 3篇 |
1985年 | 3篇 |
1984年 | 1篇 |
1983年 | 6篇 |
1982年 | 2篇 |
1981年 | 2篇 |
1980年 | 3篇 |
1978年 | 1篇 |
1974年 | 1篇 |
1962年 | 1篇 |
1961年 | 1篇 |
1958年 | 1篇 |
1956年 | 3篇 |
1955年 | 1篇 |
排序方式: 共有273条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
Genotype-phenotype correlation for nucleotide substitutions in the IgII- IgIII linker of FGFR2 总被引:6,自引:3,他引:3
5.
C Camenzuli AN DiMarco KE Isaacs Y Grant J Jackson A Alsafi C Harvey TD Barwick N Tolley FF Palazzo 《Annals of the Royal College of Surgeons of England》2021,103(1):29
IntroductionReoperative parathyroidectomy for persistent and recurrent primary hyperparathyroidism is dependent on radiology. This study aimed to compare outcomes in reoperative parathyroidectomy at a single centre using a combination of traditional and newer imaging studies.Materials and methodsRetrospective case note review of all reoperative parathyroidectomies for persistent and recurrent primary hyperparathyroidism over five years (June 2014 to June 2019; group A). Imaging modalities used and their positive predictive value, complications and cure rates were compared with a published dataset spanning the preceding nine years (group B).ResultsFrom over 2000 parathyroidectomies, 147 were reoperations (101 in group A and 46 in group B). Age and sex ratios were similar (56 vs 62 years; 77% vs 72% female). Ultrasound use remains high and shows better positive predictive value (76% vs 57 %). 99mTc-sestamibi use has declined (79% vs 91%) but the positive predictive value has improved (74% vs 53%). 4DCT use has almost doubled (61% vs 37%) with better positive predictive value (88% vs 75%). 18F-fluorocholine positron emission tomography-computed tomography and ultrasound-guided fine-needle aspiration for parathyroid hormone are novel modalities only available for group A. Both carried a positive predictive value of 100%. Venous sampling with or without angiography use has decreased (35% vs 39%) but maintains a high positive predictive value (86% vs 91%). Cure rates were similar (96% vs 100%). Group A had 5% permanent hypoparathyroidism, 1% permanent vocal cord palsy and 1% haematoma requiring reoperation. No complications for group B.ConclusionOptimal imaging is key to good cure rates in reoperative parathyroidectomy. High-quality, non-interventional imaging techniques have produced a shift in the preoperative algorithm without compromising outcomes. 相似文献
6.
Gonzales AJ; Christensen JG; Preston RJ; Goldsworthy TL; Tlsty TD; Fox TR 《Carcinogenesis》1998,19(7):1173-1183
7.
Distal catheter obstruction from non-infectious cause in ventriculo-peritoneal shunted children. 总被引:2,自引:0,他引:2
In hydrocephalic children, ventriculo-peritoneal shunting is the preferred treatment with few complications. However, an obviously non-infectious peritoneal reaction to the cerebrospinal fluid (CSF) may occasionally lead to shunt malfunction. In eight hydrocephalic children, shunt malfunction with distal catheter complication was found with abdominal pseudocyst formation in seven cases and accumulation of the CSF in one. All children had a normal CSF cell count and glucose concentration, and white cell count, and C-reactive protein in peripheral blood were normal. No CSF infection could be detected despite prolonged aerobic and anaerobic cultures. After initial externalisation of the shunt and subsequent routine administration of antibiotics because infection initially was suspected, ventriculo-peritoneal shunting was attempted one to three times with identical failure before successful conversion to a ventriculo-atrial system. At laparotomy the peritoneum and intestinal serosa were hyperaemic and oedematous in all patients, five of whom also had pseudocysts and two of whom also had intra-abdominal adhesions. Four children had a revision 6-24 years after the ventriculo-atrial conversion due to short atrial catheter with distal obstruction. In three of them, the distal catheter was successfully replaced into the peritoneal cavity. The fourth child, however, developed an infectious abdominal pseudocyst with adhesions due to a then undetected Propionibacterium acnes infection. After externalisation and antibiotics, a new ventriculo-atrial shunt was inserted. At follow-up between 5 months to nearly 6 years later, the three children with peritoneal catheters did not show any signs of shunt malfunction or abdominal problems. Thus hydrocephalic children may develop shunt malfunction with distal catheter obstruction due to a still unexplained, transient, non-infectious peritoneal reaction leading to abdominal pseudocyst formation or accumulation of CSF. In some children, however, it may later be possible to replace the distal catheter into the peritoneal cavity, if no infection is involved. 相似文献
8.
A 26‐year‐old man with a history of heavy marijuana and minimal tobacco use was found to have extensive bilateral lung bullae and interstitial fibrosis, heavily infiltrated by pigmented macrophages. These features can be associated with marijuana smoking. The differential diagnoses in this patient are also discussed. 相似文献
9.
10.
Offodile AC Lee SW Yoo J Whelan RL Moradi D Baxter R Arnell TD Nasar A Sonoda T Milsom JW Feingold DL 《Diseases of the colon and rectum》2008,51(11):1669-1674
Purpose The study investigated the impact of prior abdominal surgery on conversions and outcomes of laparoscopic right colectomy.
Methods A consecutive series of 414 patients with cancer or adenomas who underwent a laparoscopic right colectomy from March 1996
to November 2006 were studied for surgical conversions and outcomes. Conversion was defined as an incision length > 7 cm.
Results Patients with prior abdominal surgery (n = 191) were compared with patients with no prior abdominal surgery (n = 223), and
showed no significant differences in age, ASA classification, length of stay, operative time, blood loss, harvested nodes,
tumor size, and specimen length. Significantly more wound infections occurred in the prior abdominal surgery group (22 vs.12, P = 0.023). Body mass index > 30 showed a three-fold increased risk of conversion.
Fifteen percent of the no prior abdominal surgery patients and 17 percent of the prior abdominal surgery patients were converted
(P > 0.05). Conversion was associated with a longer mean length of stay (8.8 days) relative to laparoscopically completed cases
(6.3 days) regardless of prior abdominal surgery history (P < 0.0001).
Conclusions Laparoscopic right colectomy for neoplasia was not associated with a higher conversion rate or morbidity in patients with
prior abdominal surgery. Prior abdominal surgery is not a contraindication to laparoscopic right colectomy.
Presented at the 15th International Congress of the European Association of Endoscopic Surgery, Athens, Greece, July 4 to
7, 2007. 相似文献