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Tsilimigras Diamantis I. Dalmacy Djhenne Hyer J. Madison Diaz Adrian Abbas Alizeh Pawlik Timothy M. 《Annals of surgical oncology》2021,28(13):8162-8171
Annals of Surgical Oncology - Racial/ethnic disparities in cancer outcomes may relate to variations in receipt of National Comprehensive Cancer Network (NCCN) guideline compliant... 相似文献
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Oxana Palesh Karyn Haitz Francis Lévi Georg A. Bjarnason Carl Deguzman Igbal Alizeh Ayhan Ulusakarya Mary Melissa Packer Pasquale F. Innominato 《Quality of life research》2017,26(10):2783-2791
Objective
Patients with cancers frequently experience sleep and circadian dysfunction. To date, only a few studies have used both a questionnaire and actigraphy for concomitant evaluation of sleep and circadian function in patients with cancer. We sought to evaluate objective sleep and circadian parameters in metastatic colon cancer (MCC) patients and their associations with symptoms and quality of life (QOL).Methods
Patients reported subjective sleep problems on the EORTC QLQ-C30. Sleep and circadian parameters were calculated using a wrist-actigraph that patients wore for 72 h.Results
237 Patients with MCC (mean age: 60.4 years; range: 20.7–77.6; Male/Female ratio: 1.66) participated in this cross-sectional study. Subjective sleep problems were reported by 63.4% of patients (S+). No differences in any sleep parameters (sleep efficiency, sleep latency, total sleep time, total time in bed, wake after sleep onset, activity bathyphase) were observed between S+ and S? patients. However, S+ patients displayed a significantly worse circadian function than S? patients (96.4 vs 98.1%; p = 0.005). The presence of poor subjective sleep and objective circadian dysfunction negatively affected symptoms and QOL domains (p = 0.038).Conclusions
Subjective report of sleep problems was not associated with worse objectively measured sleep parameters in patients with MCC although it was associated with disrupted circadian rest-activity rhythm and poorer QOL. These findings coincide with prior research in cancer patients in that an inconsistent relationship exists between subjective and objective sleep measurements on some sleep domains. This study supports the value of coupled evaluation of self-reported and objective measures of sleep and circadian function in cancer patients.3.
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Sleep quality and its association with fatigue,symptom burden,and mood in patients with advanced cancer in a clinic for early‐phase oncology clinical trials 下载免费PDF全文
Goldy C. George PhD Eucharia C. Iwuanyanwu PHS MPAS PAC Karen O. Anderson PhD MPH Alizeh Yusuf BA Ralph G. Zinner MD Sarina A. Piha‐Paul MD Apostolia M. Tsimberidou MD PhD Aung Naing MD Siqing Fu MD PhD Filip Janku MD PhD Vivek Subbiah MD Charles S. Cleeland PhD Tito R. Mendoza PhD MS MEd David S. Hong MD 《Cancer》2016,122(21):3401-3409
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