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排序方式: 共有47条查询结果,搜索用时 31 毫秒
1.
ALDO VACCA Senior Registrar ADRIAN GRANT Epidemiologist GEOFFREY WYATT Senior Registrar IAIN CHALMERS Director 《BJOG : an international journal of obstetrics and gynaecology》1983,90(12):1107-1112
Summary. A total of 304 women, for whom operative delivery was considered necessary in the second stage of labour, were randomly assigned to delivery by vacuum extraction or forceps. Of those allocated to forceps a higher proportion of babies were actually delivered with the allocated instrument; however, the caesarean section rate was also higher in this group. Maternal trauma, use of analgesia and blood loss at delivery were significantly less in the group allocated to vacuum extraction. Vacuum extraction did, however, appear to predispose to an increase in mild neonatal jaundice. More serious neonatal morbidity was rare in both groups and the trial was of insufficient size to rule out a clinically important differential effect of the two instruments on these measures of outcome. Another trial is now needed to address this still open question more rigorously. 相似文献
2.
ANDREA CORRADO M.D. ALDO BONSO M.D. MICHELA MADALOSSO M.D. ANTONIO ROSSILLO M.D. SAKIS THEMISTOCLAKIS M.D. LUIGI DI BIASE M.D. † ‡ REA NATALE M.D. † ANTONIO RAVIELE M.D. 《Journal of cardiovascular electrophysiology》2010,21(1):1-5
Impact of the Systematic Isolation of the Superior Vena Cava. Background: Pulmonary veins (PVs) have been shown to represent the most frequent sites of ectopic beats initiating paroxysmal atrial fibrillation (AF). However, additional non-PV triggers, arising from different areas, have been reported as well. One of the most common non-PV sites described is the superior vena cava.
Aims: The purpose of the study was to investigate the impact resulting from the systematic isolation of the superior vena cava (SVCI) in addition to pulmonary vein antrum isolation (PVAI) on the outcome of paroxysmal, persistent, and permanent AF ablation.
Methods: A total of 320 consecutive patients who had been referred to our center in order to undergo a first attempt of AF ablation were randomized into 2 groups. Group I (160 patients) underwent PVAI only; Group II (160 patients) underwent PVAI and SVCI.
Results: AF was paroxysmal in 134 (46%), persistent in 75 (23%), and permanent in 111 (31%) of said patients. SVCI was performed on 134 of the 160 patients (84%) in Group II. SVC isolation was not performed on the remaining 26 patients either because of phrenic nerve capture or the lack of SVC potentials. Comparison of the outcome data between the 2 groups, after a follow-up of 12 months, revealed a significant difference in total procedural success solely with patients manifesting paroxysmal atrial fibrillation (56/73 [77%] Group I vs. 55/61 [90%] Group II; P = 0.04; OR 2.78).
Conclusions: In our study, the strategy of the empiric SVCI in addition to PVAI has improved the outcome of AF ablation solely in patients manifesting paroxysmal AF. (J Cardiovasc Electrophysiol, Vol. 21, pp. 1–5, January 2010) 相似文献
Aims: The purpose of the study was to investigate the impact resulting from the systematic isolation of the superior vena cava (SVCI) in addition to pulmonary vein antrum isolation (PVAI) on the outcome of paroxysmal, persistent, and permanent AF ablation.
Methods: A total of 320 consecutive patients who had been referred to our center in order to undergo a first attempt of AF ablation were randomized into 2 groups. Group I (160 patients) underwent PVAI only; Group II (160 patients) underwent PVAI and SVCI.
Results: AF was paroxysmal in 134 (46%), persistent in 75 (23%), and permanent in 111 (31%) of said patients. SVCI was performed on 134 of the 160 patients (84%) in Group II. SVC isolation was not performed on the remaining 26 patients either because of phrenic nerve capture or the lack of SVC potentials. Comparison of the outcome data between the 2 groups, after a follow-up of 12 months, revealed a significant difference in total procedural success solely with patients manifesting paroxysmal atrial fibrillation (56/73 [77%] Group I vs. 55/61 [90%] Group II; P = 0.04; OR 2.78).
Conclusions: In our study, the strategy of the empiric SVCI in addition to PVAI has improved the outcome of AF ablation solely in patients manifesting paroxysmal AF. (J Cardiovasc Electrophysiol, Vol. 21, pp. 1–5, January 2010) 相似文献
3.
ALDO PIETRO. MAGGIONI M.D. F.C.C.P. CLAUDIO. FRESCO M.D. MARIA GRAZIA. FRANZOSI PH.D. GIANNI. TOGNONI M.D. GISSI- INVESTIGATORS 《Journal of interventional cardiology》1990,3(3):157-168
Streptokinase (SK) and tissue plasminogen activator (alteplase [tPA]) are by far the most intensively studied thrombolytic agents, but only recently a direct head-to-head comparison (GISSI-2 Trial, in which 12,490 patients have been randomized) has become available to the scientific community. This trial, with its international extension (the International tPA/SK Mortality Trial) recruited more than 20,000 patients, showed that the two drugs tested (SK and tPA) were substantially comparable as far as the clinical events were considered. ISIS-3, the largest randomized clinical trial ever performed, compares SK, tPA, and APSAC in a factorial design. Its results will be available before spring, 1991. It is likely that these two studies, if the results will be consistent, will give a definitive answer about comparison among thrombolytic drugs. As a consequence of that achievement, the interest of the scientific community will possibly be directed towards the long-term prevention of the infarct complications, namely ventricular remodeling and infarct expansion or life-threatening arrhythmias. 相似文献
4.
Cardiac Resynchronization Therapy Delivered Via a Multipolar Left Ventricular Lead is Associated with Reduced Mortality and Elimination of Phrenic Nerve Stimulation: Long‐Term Follow‐Up from a Multicenter Registry
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JONATHAN M. BEHAR M.B.B.S. M.R.C.P. JULIAN BOSTOCK Ph.D. F.H.R.S. ADRIAN PO ZHU LI B.A. B.M.B.Ch. HUI MEN SELINA CHIN B.A. STEPHEN JUBB B.A. B.M.B.Ch. EDWARD LENT B.A.B.M. B.Ch. JAMES GAMBLE M.B.B.S. M.R.C.P. PAUL W.X. FOLEY M.D. F.R.C.P. TIM R. BETTS M.D. F.R.C.P. CHRISTOPHER ALDO RINALDI M.D. F.R.C.P. F.H.R.S. NEIL HERRING D.Phil. M.R.C.P. 《Journal of cardiovascular electrophysiology》2015,26(5):540-546
5.
MASSIMO MILANI ALDO LONGONI & MICHELA MADERNA 《British journal of clinical pharmacology》1996,42(6):782-785
Picotamide is an antiplatelet drug which inhibits thromboxane A2 (TxA2 ) synthase and antagonizes TxA2 receptors. In the ADEP (Atherosclerotic Disease Evolution by Picotamide) trial, 2304 patients with peripheral obstructive arterial disease (POAD) were studied in a double-blind, placebo-controlled, 18-month, multicentre trial. In this study, 151 events (13.1%) occurred on placebo and 122 (10.6%) on picotamide (900 mg day−1 ). The relative risk reduction was 19%, ( P =0.056). This paper reports a post-hoc analysis in a subgroup of 438 diabetic patients (picotamide=230; placebo=208). There were 32 vascular events on placebo (15%) and 18 on picotamide (8%) (relative risk reduction: 48%; 95% CI=26, 76; P =0.022). The results of this retrospective analysis suggest that a prospective study to investigate events in claudicant patients with diabetes mellitus is warranted. 相似文献
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8.
ZHONG CHEN M.B.B.S ROCIO CABRERA‐LOZOYA Ph.D. JATIN RELAN Ph.D. MANAV SOHAL M.B.B.S ANOOP SHETTY M.D. RASHED KARIM Ph.D. HERVE DELINGETTE Ph.D. JASWINDER GILL M.D. KAWAL RHODE Ph.D. NICHOLAS AYACHE Ph.D. PETER TAGGART D.Sc. CHRISTOPHER ALDO RINALDI M.D. MAXIME SERMESANT Ph.D. REZA RAZAVI M.D. 《Journal of cardiovascular electrophysiology》2016,27(7):851-860
9.
ALDO F. FINZI GIANFRANCO ALTOMARE† LUIGI BERGAMASCHINI† ANTONIA TUCCI† 《The British journal of dermatology》1981,104(3):253-256
Serum levels of retinol-binding protein (the specific carrier of vitamin A) were measured in eleven patients with pityriasis rubra pilaris and in some of their close relatives. The level of retinol-binding protein was markedly reduced in every patient, and in some of the relatives. It is postulated that defective synthesis of retinol-binding protein is a biochemical marker for pityriasis rubra pilaris, probably transmitted as a Mendelian dominant. 相似文献
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