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Malignant transformation of renal angiomyolipoma 总被引:8,自引:0,他引:8
NOBUYOSHI TAKAHASHI RYUJI KITAHARA YASUYUKI HISHIMOTO AKIMITSU OHGURO YASUHIRO HASHIMOTO TADASHI SUZUKI 《International journal of urology》2003,10(5):271-273
In the present paper, two cases of malignant transformation of renal angiomyolipoma without tuberous sclerosis are reported. Pathological examination revealed that, in both cases, in addition to the areas affected by typical angiomyolipoma, there were areas that contained elevated numbers of perivascular epithelioid cells with prominent nuclear pleomorphism. Immunohistochemical examination revealed that both cases were negative for keratin and epithelial membrane antigen, but were positive for the melanogenesis-related marker HMB-45. Metastatic diseases appeared 40 months after radical nephrectomy in the first case and 18 months in the second case. 相似文献
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