针刺联合体外冲击波治疗梨状肌综合征临床效果观察

目的观察针刺联合体外冲击波治疗梨状肌综合征的临床疗效。方法选取淮河能源控股集团有限责任公司职业病防治院(淮河能源控股集团有限责任公司职工疗养院)康复医学中心2021年2月至2022年12月收治的梨状肌综合征患者80例, 采用回顾性队列研究方法, 根据既往患者不同治疗方式分为治疗组、对照组各40例。治疗组采用针刺联合体外冲击波治疗, 针刺每天1次, 体外冲击波每7天1次, 连续治疗3周;对照组仅采用体外冲击波治疗, 每7天1次, 连续治疗3周。观察两组治疗前后视觉模拟评分法(VAS)评分变化及临床疗效。结果两组基线资料均衡可比, 差异均无统计学意义(均P > 0.05)。治疗后, 两组VAS评分均有一定下降。经协变量调整之后, 治疗组与对照组差异有统计意义(F=112.38, P < 0.001);即调整干预前VAS评分后, 治疗组VAS评分较对照组低[1.417(95%CI:1.151～1.683)]。治疗组总有效率为97.5%(39/40), 对照组总有效率为82.5%(33/40), 两组总有效率差异有统计学意义(Z=-2.03, P=0.042)。结论针刺联合体外冲击...     

尿汞的无焰原子吸收测定法(还原、气化—气液平衡)

测定尿汞的方法,国内外已有很多报导。目前,国内常用的方法有双硫腙法及蛋白碘法。这些方法干扰因素多,方法不易掌握,操作时间长。因此,日益感到不能满足要求,需要采取快速而准确的新方法。无焰原子吸收法克服了上述方法的缺点,是目前新的发展方向。我们参考了有关文献,对无焰原子吸收法测尿汞进行了条件试验,并观察了应用于临床     

内皮细胞的活化/损伤与炎症反应

炎症研究通常以白细胞组织浸润为重点,多种细胞因子错综复杂地交织呈网状,以各种不同的方式作用于白细胞的同时,也在改变着血管内皮细胞的功能,而血管内皮细胞发生的变化也影响着炎症反应的发生、发展,因此,血管内皮细胞主动参与了炎症反应并在炎症反应过程中起着重要的调控作用.本文旨在对血管内皮细胞活化/损伤在炎症反应发生和消退中作用的研究进展做一简要综述.     

直视下小鼠气管插管方法的比较

Objective To explore a safe and efficient method for endotracheal intubation in mice.Methods 60 BALB/c mice were random divided into 2 groups, direct intubation under direct vision group, ( n = 30) and direct intubation under light by transillumination group ( n = 30).After successful tracheal intubation at the first judgment, mouse received a tracheal instillation of 3 mg/kg lipopolysaccharide.Bronchoalveolar lavage (BAL) was then performed three times with 0.8 ml sterile saline.Exudate cells were centrifuged and stained with Wright's fluid.Whether the intubation indeed succeeded was judged by the amount of neutrophil infiltrated into the lungs.The mortality after intubation, the time consumed for each successful tracheal intubation and the times of attempting for intubation in two groups were assessed to approve the efficiency of two techniques.Results Eight vs.two mice died within 24 hours in two groups respectively.The time consumed for each successful tracheal intubation and success rate for the first time for two groups were (92.6 ±23.4)s vs (64.0±20.1)s and 53.3% vs 86.7% respectively, which the consumed time was significantly different, while the final success rate almost the same for the two groups.Conclusion Both direct intubation under direct vision and intubation under light by transillumination can successfully intubate the tube into the trachea.But direct intubation under direct vision by transillumination is more efficient and safe in endotracheal intubation in mice.     

“多向刺”三阳络穴为主治疗中风后手指拘挛临床观察

目的：观察“多向刺”三阳络穴为主治疗中风后手指拘挛的疗效。方法：将60例中风后手指拘挛的患者随机分为治疗组和对照组,每组各30例。治疗组“多向刺”三阳络、合谷透后溪,行平补平泻手法,留针30min,1次/d,每周5次,连续治疗4周;对照组常规抗痉挛肢体摆放、痉挛肢体牵拉和被动伸展、关节活动度训练,疗程同治疗组。结果：治疗组有效率为96.7%,对照组有效率为80.0%,2组比较差异有统计学意义;2组治疗后改良Ashworth评定分级均有不同程度减少,简化Fugl-Meyer运动功能评分法分值提高,治疗组优于对照组,差异有统计学意义。结论：“多向刺”三阳络穴为主治疗中风后手指拘挛疗效显著,在降低手指痉挛、改善运动功能方面优于常规康复训练。     

喉罩在新生儿腹腔镜疝囊高位结扎术中的应用

目的观察喉罩应用于新生儿腹腔镜下疝囊高位结扎术麻醉的临床效果。方法行腹腔镜疝囊高位结扎术的新生儿100例,出生2～28d,男86例,女14例,体重3.1～4.8kg,随机均分为喉罩组(L组)和气管插管组(T组)。术中吸入七氟醚维持麻醉。观察患儿入室时、插管(喉罩)时、手术开始5min和拔管(喉罩)时的HR、MAP,记录术后拔管(喉罩)时间、拔管(喉罩)后气道痉挛、恶心干呕、咽部红肿、声嘶和低SpO2等并发症的发生率;通过麻醉机电子挥发罐余量显示来计算两组患儿七氟醚消耗量。结果 L组患儿的插喉罩时、手术开始5min和拔喉罩时的HR明显快于、MAP明显低于T组(P<0.01)。L组拔喉罩时间明显短于T组(P<0.01),拔喉罩后呼吸道并发症以及七氟醚消耗量均低于T组(P<0.05)。结论喉罩应用于新生儿腹腔镜手术的麻醉安全可靠,较气管插管全麻用药少,拔管后并发症少,麻醉更为平稳。     

建立与完善医院财务管理新机制

解放军第一五○中心医院为适应医院发展的需求,医院及时成立了财务中心,并在实践中逐步建立和完善了充满生机与活力的财务管理体制。负责合资项目筹建与管理的财务二科,根据投资部门多、资金数量大、各合资项目独立经营性强等特点,实行“统一领导,一级核算,二级管理”的原则,在医院党委的统一领导下,既将合资项目集中进行核算,又放权各项目进行自主经营管理,贯彻责、权、利相结合的指导方针;既在总体上进行控制,又扩大各项目的自主管理权,成本与效益挂钩,效益与奖励挂钩,调动了各项目科室全体人员的主观能动性,增强了员工的主人翁责任感。     

镉对作业工人健康影响的几项指标的研究

镉在人体内不是必要的元素,体内镉蓄积增高会给人体带来一定的影响。由于镉在工业生产中的用途日益广泛,对其危害的研究也愈加引起国内外学者的重视。 研究对象 本文对冶炼厂从事水法冶炼镉的90名镉作业工人(男65人,女25人,年龄19—58岁,镉作业工龄1—29年)体内几项指标进行了研究。受检者皆为健康人,既往无肾病史、糖尿病史、肝炎史和活动性结核,体检前一周未用过有关影响化验分析的药物。 镉作业车间空气中氧化镉的浓度,在采集的20个样品中,最高浓度为4.9mg/m~3,最低浓度为0.53mg/m~3,平均浓度为1.99mg/m~3。     

直视下小鼠气管插管方法的比较

下载PDF阅读器目的 探索一种安全、高效的小鼠气管插管新方法 .方法 60只BALB/c小鼠随机分为经口直视插管组和经颈透照直视插管组,每组30只.插管成功后,气管滴入脂多糖（LPS）3 mg/kg,24 h后行左肺灌洗,将灌洗液细胞离心沉淀后经瑞氏染色,光镜下行细胞分类,根据中性粒细胞浸润情况判断插管最终成功与否.比较两组小鼠的死亡率、一次插管成功率、最终插管成功率和插管耗时.结果 两组小鼠气管插管操作完成24 h内,经口直视插管组死亡8只,经颈透照直视插管组死亡2只,差异有统计学意义（P＜0.05）.一次性插管成功率分别为53.3%和86.7%,差异有统计学意义（P＜0.01）;最终气管插管成功率为95.6%和96.4%,差异无统计学意义（P＞0.05）.气管插管时间分别为（92.6±23.4）s,（64.0±20.1）s,经组间比较T检验,差异有统计学意义（P＜0.01）.结论 两种气管插管方法 均可顺利完成气管插管.但经颈透照直视气管插管可显著提高气管插管效率,降低插管后死亡率,是小鼠试验中简捷实用安全可靠的气管插管方法 .     

Preventive effect of gastrodin on cognitive decline after cardiac surgery with cardiopulmonary bypass: A double-blind, randomized controlled study

Cognitive decline is a common complication after cardiac surgery with cardiopulmonary bypass(CPB),but as such no pharmacological therapy has been shown to be efficacious in preventing the decline.However,gastrodin has been shown to have multi-pharmacological effects on neurological functions.We undertook this study to test the hypothesis that gastrodin would potentially prevent CPB-associated neurocognitive decline.We randomly assigned 200 patients undergoing mitral valve replacement surgery to receive either gastrodin(40 mg/kg) or saline after the induction of anesthesia and subsequently evaluated cognitive function before surgery,at discharge,and at 3rd month after surgery by using a battery of five neurocognitive tests,or adverse effects of gastrodin postoperatively.Neurocognitive decline in postoperative function was defined as a drop of 1 SD or more in the scores on tests of any one of the four domains of cognitive function.Cognitive decline occurred in 9% of the patients in the gastrodin group in contrast to 42% in the control group(P<0.01) at discharge.Cognitive outcome could be determined at 3rd month in 87 patients in the gastrodin group and 89 in the control group.Cognitive decline was detected in 6% in the gastrodin group and 31% in the control group(P<0.01).The incidences of possible adverse effects were similar between two groups.These results indicate that gastrodin is an effective and a safe drug for the prevention of neurocognitive decline in patients undergoing mitral valve replacement surgery with CPB.