蒲公英辅助治疗皮肤软组织扩张器置入术后轻度感染的临床疗效观察

[目的]探讨蒲公英乙醇糊状物外敷在皮肤软组织扩张器置入术后轻度感染时期的临床疗效。[方法]对2009年6月—2014年7月行皮肤软组织扩张器置入术后轻度感染的患者病例进行临床疗效观察。56例单枚扩张器置入术后轻度感染皮瓣采用随机数字表法分为对照组(A组)和治疗组(B组),每组28例。两组均应用抗生素头孢甲肟1 g静脉滴注,每日2次。对照组扩张皮瓣应用75%乙醇纱布湿敷,每日2次;治疗组扩张皮瓣应用蒲公英乙醇糊状物纱布湿敷,每日2次。[结果]两组治疗前后红、肿症状评分、视觉模拟评分法(VAS评分)、皮温、白细胞计数水平均较治疗前有所改善,差异具有统计学意义(P0.05)。治疗组以上检测指标改善明显优于对照组,差异具有统计学意义(P0.05)。经治疗后,治疗组的治愈率为92.9%,有效率为100%,对照组的治愈率为71.4%,有效率为82.1%。治疗组的治愈率及有效率明显优于对照组,差异具有统计学意义(P0.05)。[结论]蒲公英乙醇糊状物外敷能有效辅助治疗皮肤软组织扩张器置入术后轻度感染。     

皮肤软组织扩张器置入术后感染的治疗与分析

目的:探讨扩张Ⅰ期术后感染并发症的治疗、预防及致病原因。方法:对2010年4月～2012年5月扩张Ⅰ期术后发生感染并发症病例进行回顾性研究。结果:共22人28枚扩张器置入术后感染的病例中,通过将感染严重程度分级,针对轻、中、重度感染,分别采取全身应用广谱抗生素,扩张皮瓣表面外敷蒲公英等非手术治疗;放置引流管持续滴注引流;及时行扩张Ⅱ期手术等个性化治疗方法,19人25枚轻、中度扩张器感染均得到有效控制,Ⅱ期手术顺利,效果满意。3人3枚重度感染病例,及时进行扩张Ⅱ期手术,虽疗效欠佳,但结果仍可接受,避免更大损失。结论:扩张器感染并发症发生的原因较多,重在预防,发生后需及时处理,否则后果严重。通过密切观察,结合非手术方法,采取针对性治疗,感染并发症能得到有效控制,获得满意疗效。     

胸三角皮瓣预扩张术方法的研究

目的 探讨胸三角皮瓣预扩张术的方法并预防并发症的发生.方法 本组患者214例,均行胸三角皮瓣预扩张术,术前设计选用大小合适的扩张器,术中注意剥离层次及范围,止血彻底,术后早期注水,适当固定.结果 214例患者中,8例出现扩张器感染,2例扩张皮瓣局部破溃,经及时处理后均能继续扩张,皮瓣转移后血运良好,面颈部瘢痕修复效果理想.结论 采用术前、术中、术后的综合措施预防胸三角皮瓣预扩张术并发症的发生,效果显著,为Ⅱ期手术打下良好的基础.     

自体软骨碎屑回植对肋软骨修复再生的影响

Objective To investigate the influence on costal cartilage reparative regeneration by replanting the small blocks of autogeneic cartilage into the perichondrial pocket at the donor-site. Methods 16 rabbits (8-10 weeks old, 1.8-2. 2 kg) were randomly divided into four groups as three experimental groups and one control group. The 1.5 cm in length of costal cartilage defect was made in experimental groups with the perichondrium and costochondral junction left completely intact. The cartilage defect was cloesd by 3 methods as suturation directly, or replanting the small blocks of autogeneic cartilage, or plugging bioprotein jelly after cartilage replanting. Each experimental group was handled with two methods in two sides of costal cartilage. No operation was performed in control group. All the rabbits were sacrificed 16 weeks after operation. The appearance of thoracic cage and new-formed tissue at the defect site were examined grossly. Haematoxylin-eosin staining was performed to evaluate the characteristics of new-formed tissues and biomechanical detection was used to measure intension of new-formed tissues. Results The appearance of thoracic cage was normal in every experimental group. Histological study showed that the defect was filled with abundant fibrous tissue in each group. The chipping of cartilage survived effectively with little proliferation. Biomechanical detection showed that the intension of new-formed tissue in the non replanted group [( 193. 92 ± 41. 41 ) N] was obviously less than that in the replanted group [( 318. 88 ±28. 28)N] ,or bioprotein jelly group[(301. 00 ±39. 52) N] , or control group[(300. 54 ±38. 35) N] (P <0. 01). Furthermore, there was no statistical difference between the latter three groups ( P > 0. 05 ) . Conclusions Although replanting the chipping of cartilage can' t promote reparative regeneration of hyaline cartilage, it can definitively strengthen the intensity of new-formed tissue, reinforce thoracic stability. It may also indirectly decrease the incidence rate of postoperative chest wall deformity.     

自体软骨碎屑回植对肋软骨修复再生的影响

目的 研究切取自体肋软骨后将软骨碎屑回植包埋人供区软骨膜内,对肋软骨修复和再生的影响.方法 取8～10周龄生长期雄性家兔16只随机分成4组,每组4只.实验各组在完整保留软骨膜、肋骨软骨连结处的情况下切取一段肋软骨,对缺损部位采用直接缝合、软骨碎屑回植后缝合及软骨碎屑回植加生物蛋白胶封闭空隙后缝合3种方法处理,3种处理方法在各实验组家兔两侧肋软骨中两两配对;健康对照组不做任何处理.术后16周处死家兔后观察各组胸廓及修复段的大体形态,常规HE染色病理切片,并行生物力学检测测定各肋软骨修复段的强度.结果 各实验组家兔的胸廓整体形态均较良好,各组及各处理方法之间并无明显差别;HE染色病理切片观察可见各组修复组织均主要为纤维组织,回植的小块软骨虽能够有效存活,但无明显增殖.生物力学检测显示:不回植组的修复组织强度为(193.92±41.41)N、回植组为(318.88±28.28)N、生物蛋白胶组为(301.00±39.52)N、健康对照组为(300.54±38.35)N,不回植组明显低于后3组(P<0.01).而后3组组间比较差异均无统计学意义(P>0.05).结论 将软骨碎屑回植虽不能促进透明软骨的再生修复,但能明显加强修复组织的强度,加强胸廓的稳定性,从而间接降低胸廓畸形的发生率.     

自体软骨碎屑回植对肋软骨修复再生的影响

Objective To investigate the influence on costal cartilage reparative regeneration by replanting the small blocks of autogeneic cartilage into the perichondrial pocket at the donor-site. Methods 16 rabbits (8-10 weeks old, 1.8-2. 2 kg) were randomly divided into four groups as three experimental groups and one control group. The 1.5 cm in length of costal cartilage defect was made in experimental groups with the perichondrium and costochondral junction left completely intact. The cartilage defect was cloesd by 3 methods as suturation directly, or replanting the small blocks of autogeneic cartilage, or plugging bioprotein jelly after cartilage replanting. Each experimental group was handled with two methods in two sides of costal cartilage. No operation was performed in control group. All the rabbits were sacrificed 16 weeks after operation. The appearance of thoracic cage and new-formed tissue at the defect site were examined grossly. Haematoxylin-eosin staining was performed to evaluate the characteristics of new-formed tissues and biomechanical detection was used to measure intension of new-formed tissues. Results The appearance of thoracic cage was normal in every experimental group. Histological study showed that the defect was filled with abundant fibrous tissue in each group. The chipping of cartilage survived effectively with little proliferation. Biomechanical detection showed that the intension of new-formed tissue in the non replanted group [( 193. 92 ± 41. 41 ) N] was obviously less than that in the replanted group [( 318. 88 ±28. 28)N] ,or bioprotein jelly group[(301. 00 ±39. 52) N] , or control group[(300. 54 ±38. 35) N] (P <0. 01). Furthermore, there was no statistical difference between the latter three groups ( P > 0. 05 ) . Conclusions Although replanting the chipping of cartilage can' t promote reparative regeneration of hyaline cartilage, it can definitively strengthen the intensity of new-formed tissue, reinforce thoracic stability. It may also indirectly decrease the incidence rate of postoperative chest wall deformity.     

胸三角皮瓣预扩张术后防止扩张囊移位的方法探讨

目的:探讨如何有效预防胸三角皮瓣预扩张术后扩张囊移位。方法:本组患者60例,均行胸三角皮瓣预扩张术,术前设计选用合适大小的扩张器,术中注意剥离层次及范围,止血彻底,术后早期注水、适当固定。结果:60例中扩张器均扩张良好,2例出现血肿,3例注射壶外露,经及时处理后均能继续扩张,无一例出现扩张器移位,皮瓣转移后血运良好,面颈部瘢痕修复效果理想。结论:采用术前、术中、术后的综合措施预防胸三角皮瓣预扩张时扩张器下沉移位效果显著,能基本解决扩张囊移位,为二期手术打下良好的基础。