重度有机磷农药中毒病人血清心肌酶谱及炎性指标的变化及其临床意义

目的：探讨重度有机磷农药中毒病人的心肌酶谱和炎性指标的变化规律。方法：19例重度有机磷农药中毒病人，分别检测病程1、2、3、5、7d的心肌酶谱(AST、LDH、α-HBD、CK、CK—MB)、C-反应蛋白，并与健康组(N)对照，比较各组之间指标的差异。7例重度有机磷农药中毒死亡患者心肌组织行病理学检查。结果：AST、LDH、α-HBD、CK在中毒d3升至最高，d5后逐渐趋于正常；CK—MB中毒后呈逐渐降低，但仍高于正常对照组，而CRP明显高于正常对照组，且在中毒后7d内呈逐渐升高趋势。病理学检查发现心肌中有大量白细胞浸润。结论：CRP和心肌酶谱测定对于监测病情，预测病情危险性有重要意义，可作为重度有机磷农药中毒患者的常规血清检测指标。     

Effect of Homoharringtonine on Corneal Haze after Excimer Laser Photorefractive Keratectomy in Rabbits

To evaluate the inhibiting effect of Homoharringtonine （HHT） on the corneal haze after excimer laser photorefractive keratectomy （PRK） in rabbits. 18 healthy rabbits which underwent PRK were randomly divided into three groups （A, B and C）. The refractive degree of ablation was - 10.0DS in each group. Group A was locally treated with a piece of filter paper soaked with 1 mg/ mL HHT for 5 min, and then the entire cornea was repeatedly irrigated with balance solution; Group B was dropped with 0.1 mg/mL HHT after PRK for 3 months; Group C was the control group, Corneal haze, histopathology, response, ect. were investigated. The corneal haze was significantly less in group A, while the difference between group B and group C was insignificant. Keratocytes and fibrocytes in corneal stroma were more active up to 3 months in group B and group C, Intraoperative use of topical HHT can reduce corneal haze after PRK in rabbits.     

唇珠重建术的探讨

目的：探讨一种简便的唇珠重建方法。方法：在上唇口内近边缘处作倒V形切开,应用V-Y改形原理,将皮瓣往唇缘处推进,加上唇系带二侧旋转瓣相嵌缝合,重建唇珠。结果：皮瓣血运、存活良好,重建唇珠外形满意,表面看不到瘢痕,是一种简单、方便、理想的唇珠重建方法。随访3～15个月,平均12个月,皮瓣质地优良,瘢痕不明显,无挛缩,唇形生动自然,立体感强。远期效果满意。结论：运用V-Y改形术加上唇系带二侧旋转瓣相嵌缝合术是进行唇珠重建的理想术式。手术设计及操作简便,皮瓣血运可靠,能理想地重建缺损的唇珠,术后不挛缩,瘢痕不明显,远期效果可靠。     

鼻侧腱膜内固定法内眦赘皮矫正术

目的：探讨一种矫正内眦赘皮更简单、切口隐蔽、瘢痕不明显的术式。方法：通过重睑线鼻侧小切口将内眦赘皮皮下筋膜、内眦韧带及眼轮匝肌肌纤维充分松解、分离,部分切除,把内眦赘皮向鼻侧腱膜推移,并将内眦赘皮皮下包括部分真皮缝合固定在鼻侧腱膜上。结果：通过此方法矫正轻、中度内眦赘皮240例。144例获随访,最短1月,最长1年,内眦赘皮消失。11例术后出现线结反应硬结形戍占7．6％,3～6个月消失;6例效果欠佳内眦赘皮复发占4．2％,半年后再用此方法修复矫正得到满意效果。结论：此方法手术创伤小,恢复时间短,术后瘢痕不明显,是内眦赘皮矫正的一种有效适用方法。