原发性肾滑膜肉瘤一例报告并文献复习

Objective To discuss the presentations, pathologic features, diagnosis and treatment of primary synovial sarcoma of the kidney. Methods One case of primary synovial sarcoma of the kidney was reported and the relevant literature was reviewed. A 55-year-old man was admitted with complaint of right abdomen and flank pain for 5 h. Computerized tomography revealed a 12.5 cm × 11.0 cm × 9. 0 cm mass located at the middle and lower pole of the right kidney. The patient was taken radical nephrectomy. Results The diagnosis of primary synovial sarcoma of the kidney in the patient was confirmed by postoperative pathology. Under microscope, tumor was typically mitotically active, monomorphic spindle cells growing in intersecting fascicles or in solid sheets with epithelial differentiation. In some areas a haemangiopericytoma-like pattern was found. Immunohistochemical staining showed that the tumor cells were positive for the markers Vimentin, CD99 and Bcl-2, but CK was negative. The patient died of local recurrence and multi-metastasis at 8 months after surgery. Conclusions Primary synovial sarcoma of the kidney is extremely rare with a high grade of malignancy,and its prognosis is poor. The diagnosis depends on pathological features, Immunohistochemical studies and RT-PCR detection. Radical resection combined with chemicaltherapy is considered to be the most reliable treatment so far.     

原发性肾滑膜肉瘤及术后复发、转移的影像学表现

目的探讨原发性肾滑膜肉瘤(primary renal synovial sarcoma,PRSS)及术后复发、转移的影像特征,以提高对该病的诊断和鉴别诊断的水平。资料与方法回顾性分析1例PRSS的临床、影像、病理、免疫组织化学以及术后随访资料,结合文献探讨PRSS及其术后复发、转移的影像学征象与临床和病理表现间的关系。结果 CT像上呈不均匀强化的囊实性肿物,大小约10.7 cm×12.3 cm×15.5 cm,肿块外缘可见出血;腰大肌受累;腹膜后未见淋巴结,双肺未发现转移病灶。超声探及右肾回声不均包块,边界略清,内中强回声和多发囊性回声区,多分隔,肿瘤内"星点"状血流信号。镜下瘤细胞呈"梭"形、束状排列,细胞异型,可见核分裂像;免疫组织化学染色:波形蛋白(Vimentin)、CD99、癌基因(Bcl-2)阳性,细胞角蛋白(CK)阴性。术后随访出现局部复发及肺转移,术8个月后死亡。结论 PRSS是一种罕见的恶性肿瘤,预后差,其影像学表现具有一定特征性,但确诊需依靠病理、免疫组织化学和SYT-SSX融合基因检测。CT在诊断肿瘤良恶性、肿瘤分期和随访方面有重要价值。     

1419份归档病历的院内感染调查分析

为了掌握我院目前住院病人的院内感染发病情况,我们调查了1990年第一季度的全部入档病历1680份,实查1419份,现调查分析如下。一、调查方法根据病历材料中的有关记录,如病历首页上的入、出院诊断,院内合併症及院内感染栏目的填写、体温单上体温曲线的变化,大小便次数记录、医嘱单上抗菌素的更改与增添、病程记录以及各种有关检验、检查报告单等,找出医院内感染的诊断依据。二、医院内感染诊断标准根据江苏省卫生厅颁发的“院内感染诊断标准”。三、调查结果见表1、2。由表1可以看出,我院目前的院内感染发生率为     

原发性肾滑膜肉瘤一例报告并文献复习

目的 总结原发性肾滑膜肉瘤的临床表现、病理特点和诊治方法.方法 原发性肾滑膜肉瘤患者1例,男,55岁.因右腰背及上腹部疼痛5 h入院.无尿频、尿急、尿痛、血尿、发热等症状.CT检查示右肾中下极恶性占位可能,累及右肾门、肾动静脉及肝脏.行右肾肿瘤根治性切除术.结果 病理检查:肿瘤大小12.5 cm×11.0 cm×9.0 cm.镜下瘤细胞呈梭形、束状排列,细胞异型,可见核分裂相,部分区域见增生的薄壁血管,肿瘤呈浸润性生长,伴发炎症及大量坏死、出血.免疫组化染色示Vimentin、CD99、Bcl-2阳性,CK阴性.病理诊断为原发性肾滑膜肉瘤.患者术后2个月出现局部复发及肝肺转移,予异环磷酰胺、表阿霉素化疗1疗程,患者不能耐受.术后8个月死亡.结论 原发性肾滑膜肉瘤是一种罕见、高度恶性的肿瘤,预后不良,确诊需依赖病理检查、免疫组织化学及RT-PCR检测.根治性切除辅以化学治疗可行.     

应用普通膀胱镜气压弹道碎石治疗膀胱结石(附21例报告)

目的探讨气压弹道碎石术治疗膀胱结石的新方法。方法经膀胱镜置入气压弹道碎石设备，将膀胱结石击碎并取出。结果21例均顺利碎石并一次性将结石取尽。术中、术后无大出血、膀胱穿孔、黏膜损伤和水中毒等并发症。21例术后随访3～18个月，平均4．5个月。B超或KUB未见结石复发，无排尿不畅等尿道狭窄症状。结论应用普通膀胱镜气压弹道碎石是处理膀胱结石经济有效的治疗方法。     

两步法建立标准通道经皮肾镜取石术治疗上尿路结石:附208例报告

目的 探讨应用两步法建立标准皮肾通道经皮肾镜取石术的安全性和有效性.方法 2007年11月至2010年12月,应用彩超引导下两步法建立标准通道经皮肾镜取石术治疗上尿路结石患者208例,共235侧上尿路结石,其中包括:孤立肾12例,肾盏憩室合并结石3例,髓质海绵肾3例.结石纵径1.7~8.0 cm,横径1.6~5.5 cm.结果 208例均一期成功建立经皮肾镜碎石通道.203例行一期取石术,5例行二期取石术.平均通道建立时间15.7±12.3 min,平均手术时间72.6±33.9 min.一期手术清石率88.5%,二期手术清石率为93.6%.术中、术后输血患者16例.并发液气胸1例,灌注液外渗3例,无感染性休克及肠道、肝、脾等腹腔脏器损伤.结论 两步法建立标准皮肾通道的经皮肾镜取石术是安全和有效的方法.     

泌尿系硅结石1例

<正>我院收治1例泌尿系结石患者,其成分为"硅结石",现报道如下。1病例报告患者女性,53岁,农民,因"左腰腹部疼痛3月"入院,在当地医院诊断泌尿系结石,行4次体外震波碎石治疗,未排出结石。既往体健。泌尿系CT提示单个结石,位于左输尿管中上段,第四腰椎平面,1.3cm×1.0cm×1.0cm,CT值:最小值为366 Hu,最     

输尿管镜下碎石清石术治疗输尿管上段、肾盂及肾上盏结石(附30例报告)

目的 探讨输尿管镜下应用瑞士EMS三代碎石、清石设备处理输尿管上段结石、肾盂及肾上盏内结石的临床疗效.方法 2005年12月～2008年5月,用上述方法治疗结石30例.结石大小:长径1.2～2.2 cm,横径0.8～1.2 cm,并发中重度肾积水21例,28例曾行体外冲击波碎石治疗.结果 30例中28例1次碎石成功,成功率93.3%.失败的2例中有1例因输尿管呈"N"扭曲致进镜失败而改行开放手术,1例有较大的肾孟结石碎石后残留结石,留置D-J管后行体外冲击波碎石治疗.结论 榆尿管镜下气压弹道联合超声碎石设备处理榆尿管上段、肾盂及肾上盏内结石可以取得良好的治疗效果.     

原发性肾滑膜肉瘤一例报告并文献复习

Objective To discuss the presentations, pathologic features, diagnosis and treatment of primary synovial sarcoma of the kidney. Methods One case of primary synovial sarcoma of the kidney was reported and the relevant literature was reviewed. A 55-year-old man was admitted with complaint of right abdomen and flank pain for 5 h. Computerized tomography revealed a 12.5 cm × 11.0 cm × 9. 0 cm mass located at the middle and lower pole of the right kidney. The patient was taken radical nephrectomy. Results The diagnosis of primary synovial sarcoma of the kidney in the patient was confirmed by postoperative pathology. Under microscope, tumor was typically mitotically active, monomorphic spindle cells growing in intersecting fascicles or in solid sheets with epithelial differentiation. In some areas a haemangiopericytoma-like pattern was found. Immunohistochemical staining showed that the tumor cells were positive for the markers Vimentin, CD99 and Bcl-2, but CK was negative. The patient died of local recurrence and multi-metastasis at 8 months after surgery. Conclusions Primary synovial sarcoma of the kidney is extremely rare with a high grade of malignancy,and its prognosis is poor. The diagnosis depends on pathological features, Immunohistochemical studies and RT-PCR detection. Radical resection combined with chemicaltherapy is considered to be the most reliable treatment so far.