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1.
膀胱尿路上皮癌患者外周血T淋巴细胞凋亡蛋白Fas的表达   总被引:1,自引:0,他引:1  
Objective To investigate the relationship between the Fas expression in peripheral blood T cells and bladder transitional cell carcinoma (TCC). Methods The Fas expression in peripheral blood T cells of 52 patients with TCC and 37 healthy people was detected by flowcytometry. The Fas-posi-tive rate was compared by t test between two designed groups. Results The Fas expression in CD4+ [(20.74±9.02)%] and CD8+[ (7.51±5.93 )% ] was increased in TCC patients as compared with controls ( P < 0. 01 ). Fas-positive CD8+ ceils were reduced in invasive TCC as compared with superficial TCC [ ( 5. 83±3.95 ) % vs ( 5. 83±3.95 ) %, P < 0.05 ], but there was no difference between primary and recurrent cases ( P > 0.05 ). Conclusion The abnormal Fas expression in peripheral blood T cells may play an important role in the development and progression of TCC.  相似文献   
2.
Objective To investigate the relationship between the Fas expression in peripheral blood T cells and bladder transitional cell carcinoma (TCC). Methods The Fas expression in peripheral blood T cells of 52 patients with TCC and 37 healthy people was detected by flowcytometry. The Fas-posi-tive rate was compared by t test between two designed groups. Results The Fas expression in CD4+ [(20.74±9.02)%] and CD8+[ (7.51±5.93 )% ] was increased in TCC patients as compared with controls ( P < 0. 01 ). Fas-positive CD8+ ceils were reduced in invasive TCC as compared with superficial TCC [ ( 5. 83±3.95 ) % vs ( 5. 83±3.95 ) %, P < 0.05 ], but there was no difference between primary and recurrent cases ( P > 0.05 ). Conclusion The abnormal Fas expression in peripheral blood T cells may play an important role in the development and progression of TCC.  相似文献   
3.
Objective To investigate the relationship between the Fas expression in peripheral blood T cells and bladder transitional cell carcinoma (TCC). Methods The Fas expression in peripheral blood T cells of 52 patients with TCC and 37 healthy people was detected by flowcytometry. The Fas-posi-tive rate was compared by t test between two designed groups. Results The Fas expression in CD4+ [(20.74±9.02)%] and CD8+[ (7.51±5.93 )% ] was increased in TCC patients as compared with controls ( P < 0. 01 ). Fas-positive CD8+ ceils were reduced in invasive TCC as compared with superficial TCC [ ( 5. 83±3.95 ) % vs ( 5. 83±3.95 ) %, P < 0.05 ], but there was no difference between primary and recurrent cases ( P > 0.05 ). Conclusion The abnormal Fas expression in peripheral blood T cells may play an important role in the development and progression of TCC.  相似文献   
4.
Objective To investigate the relationship between the Fas expression in peripheral blood T cells and bladder transitional cell carcinoma (TCC). Methods The Fas expression in peripheral blood T cells of 52 patients with TCC and 37 healthy people was detected by flowcytometry. The Fas-posi-tive rate was compared by t test between two designed groups. Results The Fas expression in CD4+ [(20.74±9.02)%] and CD8+[ (7.51±5.93 )% ] was increased in TCC patients as compared with controls ( P < 0. 01 ). Fas-positive CD8+ ceils were reduced in invasive TCC as compared with superficial TCC [ ( 5. 83±3.95 ) % vs ( 5. 83±3.95 ) %, P < 0.05 ], but there was no difference between primary and recurrent cases ( P > 0.05 ). Conclusion The abnormal Fas expression in peripheral blood T cells may play an important role in the development and progression of TCC.  相似文献   
5.
Objective To investigate the relationship between the Fas expression in peripheral blood T cells and bladder transitional cell carcinoma (TCC). Methods The Fas expression in peripheral blood T cells of 52 patients with TCC and 37 healthy people was detected by flowcytometry. The Fas-posi-tive rate was compared by t test between two designed groups. Results The Fas expression in CD4+ [(20.74±9.02)%] and CD8+[ (7.51±5.93 )% ] was increased in TCC patients as compared with controls ( P < 0. 01 ). Fas-positive CD8+ ceils were reduced in invasive TCC as compared with superficial TCC [ ( 5. 83±3.95 ) % vs ( 5. 83±3.95 ) %, P < 0.05 ], but there was no difference between primary and recurrent cases ( P > 0.05 ). Conclusion The abnormal Fas expression in peripheral blood T cells may play an important role in the development and progression of TCC.  相似文献   
6.
目的 探讨膀胱尿路上皮癌与Fas介导的血T淋巴细胞凋亡的关系.方法 应用流式细胞仪检测52例膀胱癌患者和37例健康对照者外周血CD4Fas、CD8Fas阳性T细胞.结果 膀胱癌患者外周血CIM、CD8Fas阳性T细胞分别为(20.74±9.02)%、(7.51±5.93)%,对照组分别为(15.68±5.58)%、(4.27±3.08)%,肿瘤组较对照组明显增加(P<0.01).浸润组CD8Fas阳性T细胞数为(5.83±3.95)%,表浅组为(5.83±3.95)%,浸润组较表浅组明显降低(P<0.05).复发组CD4、CD8Fas阳性T细胞与初发组比较筹异无统计学意义(P>0.05).结论 血T淋巴细胞Fas表达的异常可能在膀胱癌的发生发展中起重要的作用.  相似文献   
7.
目的 探讨膀胱癌TURBt术后继发膀胱结石的病因、诊断及治疗疗效.方法 总结分析2006~2008年随访的276例膀胱癌行TURBt的患者,其中16例术后继发膀胱结石的临床资料.结果 16例患者均表现为膀胱附壁结石,经B超、腹部平片及膀胱镜检查确诊,采用膀胱镜下钬激光碎石治疗,结石排净率100%.结论 TURBt术后瘢痕形成与膀胱继发结石关系密切,经膀胱镜钬激光是治疗膀胱附壁结石的有效方法.  相似文献   
8.
目的 探讨输尿管硬镜结合输尿管软镜钬激光碎石术治疗复杂性输尿管上段结石患者的临床效果.方法 回顾性分析2018年6月至2020年6月医院收治的102例复杂性输尿管上段结石患者的临床资料,根据手术方式的不同分为对照组和试验组,每组51例.对照组行输尿管硬镜钬激光碎石术,试验组行输尿管硬镜结合输尿管软镜钬激光碎石术,比较两...  相似文献   
9.
Objective To investigate the relationship between the Fas expression in peripheral blood T cells and bladder transitional cell carcinoma (TCC). Methods The Fas expression in peripheral blood T cells of 52 patients with TCC and 37 healthy people was detected by flowcytometry. The Fas-posi-tive rate was compared by t test between two designed groups. Results The Fas expression in CD4+ [(20.74±9.02)%] and CD8+[ (7.51±5.93 )% ] was increased in TCC patients as compared with controls ( P < 0. 01 ). Fas-positive CD8+ ceils were reduced in invasive TCC as compared with superficial TCC [ ( 5. 83±3.95 ) % vs ( 5. 83±3.95 ) %, P < 0.05 ], but there was no difference between primary and recurrent cases ( P > 0.05 ). Conclusion The abnormal Fas expression in peripheral blood T cells may play an important role in the development and progression of TCC.  相似文献   
10.
Objective To investigate the relationship between the Fas expression in peripheral blood T cells and bladder transitional cell carcinoma (TCC). Methods The Fas expression in peripheral blood T cells of 52 patients with TCC and 37 healthy people was detected by flowcytometry. The Fas-posi-tive rate was compared by t test between two designed groups. Results The Fas expression in CD4+ [(20.74±9.02)%] and CD8+[ (7.51±5.93 )% ] was increased in TCC patients as compared with controls ( P < 0. 01 ). Fas-positive CD8+ ceils were reduced in invasive TCC as compared with superficial TCC [ ( 5. 83±3.95 ) % vs ( 5. 83±3.95 ) %, P < 0.05 ], but there was no difference between primary and recurrent cases ( P > 0.05 ). Conclusion The abnormal Fas expression in peripheral blood T cells may play an important role in the development and progression of TCC.  相似文献   
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