膀胱全切改良 Sigma 直肠膀胱术 10 例临床疗效分析

Objectives To discuss The clinical effect study of 10 cases modified Sigma rectum pouch after radical cystectomy.Methods 10 male patients had been performed modified Sigma rectum pouch from Jan.2006 to Jan.2008.A segment of Sigmoid colon was folded and a longitudinal incision about 25cm Was made on the Sigmoid wall and the incision was sutured so as to form a low pressure pouch.The ends of the 2 ureters were anastomosed to - gether to form a big nipple and Wag then drawn into the top of the pouch for 2～3cm and the ureteroSigmoidostomy was accomplished.Results The operative time of modified Signm rectum pouch took 60min.10 cases had been followed up for 5～24months with a mean of 16 months and good urinary continence without acid - base dysequilibri - um.A slight unilateral hydronephrosis occurred in 1 cage.Conclusions The method is the character of short time,a few complication good continence,as well as ,according with physiological requirement.The life quality of patients would be markedly improved.     

一种双侧供肾大鼠肾移植模型的建立

目的 探讨同时取大鼠双侧肾脏分别移植的可行性，其目的是节省实验费用、缩短手术时间。方法 以近交系Brown-Norway大鼠为供者，同时取其双肾作为供肾，原位灌洗；近交系Lewis大鼠为受者，切除其左肾，移植供肾1只。以冠状动脉造影支架为支撑行供肾静脉与受者肾静脉端端吻合，供肾动脉与受者的腹主动脉行端侧吻合，供肾输尿管膀胱瓣与受者的膀胱吻合。受者术中预置右侧肾脏血管体外结扎线，术后3d结扎。结果 每只供鼠手术耗时约40min，热缺血时间约10S，冷缺血时间约20min。40次实验均获成功，移植肾功能正常，在不用免疫抑制剂的情况下，受者存活时间均超过7d。结论 同时取双侧肾脏分别移植给2个受者是可行的，可降低实验成本；要获得相同数量的供肾，同时取双肾的耗时较仅取单侧肾脏大大缩短。     

腰椎峡部裂性滑脱伴骨化性蛛网膜炎1例报告

患者男性，59岁。因“腰痛10年，加重伴右下肢放射痛、麻木20d”于2006年8月4日入院。患者10年前无明显外伤或其他诱闲出现腰背部疼痛，站立负重、活动时加重，休息后稍缓解。20d前腰痛加重，井向右下肢放射，有麻木感，下肢无力、行走困难。1周前曾在外院就诊，行MRI检查示L3／4～L5／S1水平椎管内异常信号、L4椎体I度滑脱、L3／4～L5S1椎间盘膨出。     

305例尿石成份分析及预防对策

目的研究一种快速、简便的方法对泌尿系结石进行分析,并探讨其防治方法。方法用化学常量法对305例患者的尿石标本进行化学成份测定,并结合临床资料进行分析。结果发现结石发病男性多于女性(比例为3.2∶1),20~50岁多发,上尿路结石多于下尿路结石(5.4∶1)。结石中草酸钙检出率达82%,尿酸盐55.2%,磷酸钙48.6%,磷酸镁铵与碳酸磷灰石则多见于泌尿系感染病例,胱氨酸结石少见。结论化学常量法分析泌尿系结石简便、快捷、准确。结石成份分析对于了解结石成因、预防结石复发具有一定的意义。     

射精管异位开口于苗勒管囊肿

报告２例射精管异位开口于苗勒管囊肿。均以血精、血尿就诊，通过经皮输精管穿刺造影及染色尿道镜检查确诊。经抗炎及窥视下纵行剪开苗勒管囊肿前壁。１例治愈，１例好转。对本病的病因、临床表现、诊断、治疗及预后进行了讨论。     

肾细胞癌中血管内皮生长因子的表达

目的 探讨肾癌组织中血管内皮生长因子的表达及其与肾癌生物学行为的关系。方法 应用单克隆鼠抗-VEGF抗体通过免疫组化SP法研究肾癌中血管内皮生长因子的表达。结果 60例肾癌组织中35例(58.3％)血管内皮生长因子阳性。血表达与组织学分级(P<0.05)和TNM分期(P<0.05)均明显相关。 结论 血管内皮生长因子表达对肾癌生物学行为有重要影响,设法抑制血管内皮生长因子有望成为肾癌治疗的另一有效方法。     

前列腺穿刺活检

前列腺癌的确诊需通过前列腺穿刺活检获得癌性组织，近年来前列腺穿刺活检的适应证和技术方法不断得到改进和完善，本文就前列腺穿刺活检的适应证和方法的最新进展作一综述。     

Expression of the calcium receptor CaR in the parathyroid of secondary hyperparathyroidism patients

The effects of calcium on parathyroid hormone (PTH) has further discovered in recent years. It has been known that calcium ion concentration in the extracellular fluid is a major determinant of PTH secretion. The relationship between serum intact PTH (iPTH) and calcium ion levels is described by a sigmoidal curve. The calcium concentration that produces half-maximal change in PTH release (the midpoint between maximal and minimal     

血和尿中人绒毛膜促性腺激素含量与膀胱肿瘤生物学行为的…

用放射免疫方法检测２１例膀胱肿瘤患者和同例数泌尿科非肿瘤患者血和尿中人绒毛膜促性腺激素含量。试验组血样本β－ＨＣＧ均值为１８．２３ＩＵ／Ｌ，对照组为６．６０ＩＵ／Ｌ，Ｐ〈０．０２５，试验组尿β－ＨＣＧ均值为４９．９ＩＵ／Ｌ，对照组为７．３４ＩＵ／ＬＯ，Ｐ〈０．０２５。     

阴茎海绵体折叠术治疗单纯阴茎下弯

对１９例先天性单纯阴茎下弯采用阴茎海绵体折叠术矫治，即在弯曲的凸面白膜折叠缝合以拉直阴茎，为减少并发症，同时加以改进措施。所有病例随访１０～７１个月，手术效果满意