全文获取类型
收费全文 | 1322篇 |
免费 | 139篇 |
国内免费 | 35篇 |
专业分类
耳鼻咽喉 | 33篇 |
儿科学 | 51篇 |
妇产科学 | 5篇 |
基础医学 | 152篇 |
口腔科学 | 36篇 |
临床医学 | 93篇 |
内科学 | 297篇 |
皮肤病学 | 21篇 |
神经病学 | 83篇 |
特种医学 | 148篇 |
外科学 | 221篇 |
综合类 | 56篇 |
一般理论 | 1篇 |
预防医学 | 99篇 |
眼科学 | 7篇 |
药学 | 66篇 |
中国医学 | 1篇 |
肿瘤学 | 126篇 |
出版年
2018年 | 12篇 |
2016年 | 14篇 |
2015年 | 20篇 |
2014年 | 22篇 |
2013年 | 27篇 |
2012年 | 54篇 |
2011年 | 40篇 |
2010年 | 25篇 |
2009年 | 23篇 |
2008年 | 37篇 |
2007年 | 56篇 |
2006年 | 47篇 |
2005年 | 33篇 |
2004年 | 35篇 |
2003年 | 40篇 |
2002年 | 25篇 |
2001年 | 35篇 |
2000年 | 30篇 |
1999年 | 31篇 |
1998年 | 33篇 |
1997年 | 31篇 |
1996年 | 22篇 |
1995年 | 30篇 |
1994年 | 32篇 |
1993年 | 22篇 |
1992年 | 22篇 |
1991年 | 24篇 |
1990年 | 35篇 |
1989年 | 27篇 |
1988年 | 28篇 |
1987年 | 26篇 |
1986年 | 36篇 |
1985年 | 39篇 |
1984年 | 34篇 |
1983年 | 20篇 |
1982年 | 21篇 |
1981年 | 21篇 |
1980年 | 17篇 |
1979年 | 19篇 |
1978年 | 19篇 |
1977年 | 14篇 |
1976年 | 20篇 |
1975年 | 20篇 |
1974年 | 19篇 |
1973年 | 16篇 |
1971年 | 18篇 |
1970年 | 29篇 |
1968年 | 20篇 |
1967年 | 25篇 |
1966年 | 23篇 |
排序方式: 共有1496条查询结果,搜索用时 0 毫秒
1.
2.
Neurological paraneoplastic syndromes in patients with small cell lung cancer. A prospective survey of 150 patients. 总被引:1,自引:1,他引:0 下载免费PDF全文
G M Elrington N M Murray S G Spiro J Newsom-Davis 《Journal of neurology, neurosurgery, and psychiatry》1991,54(9):764-767
One hundred and fifty patients presenting with small cell lung cancer (SCLC) to chest physicians, were assessed neurologically. Neuromuscular or autonomic deficits were common and occurred in up to 44% of cases. Weakness, dry mouth, and weight loss were not mutually independent and may represent the syndrome formerly described as carcinomatous neuromyopathy. By contrast, undoubted paraneoplastic syndromes were much less commonly detected. Two patients had the Lambert-Eaton myasthenic syndrome (LEMS) and one had subacute sensory neuropathy (SSN). In these patients, neurological symptoms antedated other manifestations of cancer, by between six and 17 months. The 95% confidence interval for the prevalence of LEMS or SSN among SCLC patients was 0-4%, consistent with the results of previous retrospective or smaller studies: summing these, the overall prevalence of LEMS among SCLC patients is close to 3%, which implies about 250 new cases per annum in England and Wales. If LEMS and SSN are the least uncommon neurological paraneoplastic syndromes in SCLC patients, this may reflect the accessibility of motor nerve terminals and dorsal root ganglia to cross-reactive anti-tumour cell antibodies. 相似文献
3.
Stage means more than grade in adenoid cystic carcinoma. 总被引:10,自引:0,他引:10
Our experience with 184 previously untreated patients who had adenoid cystic carcinoma of salivary gland origin is reviewed. Retrospective staging was possible in all but nine patients who had minor salivary gland primary tumors. Sixty-three percent of patients were diagnosed as having stage I or stage II disease (stage I, 64 patients; stage II, 47 patients), whereas 43 and 21 patients had stage III and IV tumors, respectively. Grading was as follows: cribriform pattern only (grade 1, 126 patients; 68%), mixed cribriform and solid features (grade 2, 48 patients; 26%), and solid only (grade 3, 10 patients; 5%). Treatment was predominantly surgical (174 patients), and relatively few patients received adjunctive, postoperative irradiation (27 patients). Cumulative 10-year survival was 75%, 43%, and 15% for stage I, stage II, and stage III and IV patients, respectively, and cause-specific survival at 10 years was as high as 94% in patients with stage I disease. Only the clinical stage had a significant impact on survival. Neither survival, regional metastases (16 patients; 11%), nor distant dissemination (64 patients; 43%) was predictable on the basis of tumor grade alone. The prognosis in patients with early stage lesions may be better than has been appreciated. 相似文献
4.
5.
6.
The indications for elective treatment of the neck in cancer of the major salivary glands. 总被引:8,自引:0,他引:8
J G Armstrong L B Harrison H T Thaler H Friedlander-Klar D E Fass M J Zelefsky J P Shah E W Strong R H Spiro 《Cancer》1992,69(3):615-619
To define the indications for elective neck treatment, the cases of 474 previously untreated patients were reviewed who had locally confined major salivary gland cancers treated between 1939 and 1982. Clinically positive nodes were present in 14% (67 of 474). Overall, clinically occult, pathologically positive nodes occurred in 12% (47 of 407). By univariate analysis, several factors appeared to predict the risk of occult metastases; however, multivariate analysis revealed that only size and grade were significant risk factors. Tumors 4 cm or more in size had a 20% (32 of 164) risk of occult metastases compared with a 4% (nine of 220) risk for smaller tumors (P less than 0.00001). High-grade tumors (regardless of histologic type) had a 49% (29 of 59) risk of occult metastases compared with a 7% (15 of 221) risk for intermediate-grade or low-grade tumors (P less than 0.00001). In view of the low frequency of occult metastases in the entire group, routine elective treatment of the neck is not recommended. High-grade tumors and larger tumors have a high rate of occult neck metastases, and treatment should be considered in this group. 相似文献
7.
We reviewed the records of 104 patients with Stage T1NO or Stage T2NO epidermoid carcinoma of the supraglottic larynx treated between 1965 and 1979. In 79 patients, surgery was the only type of initial treatment. These 79 patients are the subjects of this report. Forty-eight (61%) of these patients were treated by total laryngectomy, whereas 31 (39%) had a partial laryngectomy. An elective unilateral radical neck dissection was performed on 31 patients considered at high risk, but metastatic disease was found in the dissected side of the neck histologically in only 32% (ten of 31) of these patients. The minimum follow-up period was 5 years and the maximum was 20 years. Twenty-nine percent of the patients (23 of 79) experienced a neck relapse. The neck relapse rate was the same whether the patients did or did not have an elective radical neck dissection. Among the patients who experienced a neck relapse, 65% (15 of 32) have died of the cancer. Among those who did not experience a neck relapse, none (zero of 56) have died of the cancer (P less than 0.01). These results indicate that in surgically treated patients with early stage supraglottic larynx cancer, neck relapse was the major cause of failure associated with death from cancer. Strategies for decreasing the relapse rate are discussed. 相似文献
8.
What is empathy and can it be taught? 总被引:11,自引:0,他引:11
H Spiro 《Annals of internal medicine》1992,116(10):843-846
Empathy is the "almost magical" emotion that persons or objects arouse in us as projections of our feelings. Empathy requires passion, more so than does equanimity, so long cherished by physicians. Medical students lose some of their empathy as they learn science and detachment, and hospital residents lose the remainder in the weariness of overwork and in the isolation of the intensive care units that modern hospitals have become. Conversations about experiences, discussions of patients and their human stories, more leisure and unstructured contemplation of the humanities help physicians to cherish empathy and to retain their passion. Physicians need rhetoric as much as knowledge, and they need stories as much as journals if they are to be more empathetic than computers. 相似文献
9.
10.