全文获取类型
收费全文 | 431篇 |
免费 | 17篇 |
专业分类
儿科学 | 8篇 |
妇产科学 | 1篇 |
基础医学 | 41篇 |
口腔科学 | 1篇 |
临床医学 | 28篇 |
内科学 | 74篇 |
神经病学 | 12篇 |
特种医学 | 116篇 |
外科学 | 85篇 |
综合类 | 3篇 |
预防医学 | 30篇 |
眼科学 | 4篇 |
药学 | 17篇 |
肿瘤学 | 28篇 |
出版年
2023年 | 1篇 |
2022年 | 5篇 |
2021年 | 16篇 |
2020年 | 9篇 |
2019年 | 9篇 |
2018年 | 13篇 |
2017年 | 6篇 |
2016年 | 11篇 |
2015年 | 15篇 |
2014年 | 23篇 |
2013年 | 20篇 |
2012年 | 18篇 |
2011年 | 23篇 |
2010年 | 14篇 |
2009年 | 10篇 |
2008年 | 17篇 |
2007年 | 29篇 |
2006年 | 32篇 |
2005年 | 29篇 |
2004年 | 26篇 |
2003年 | 20篇 |
2002年 | 20篇 |
2001年 | 16篇 |
2000年 | 16篇 |
1999年 | 8篇 |
1998年 | 7篇 |
1997年 | 8篇 |
1996年 | 3篇 |
1995年 | 3篇 |
1994年 | 5篇 |
1993年 | 1篇 |
1992年 | 3篇 |
1990年 | 3篇 |
1988年 | 1篇 |
1987年 | 1篇 |
1985年 | 2篇 |
1982年 | 2篇 |
1981年 | 1篇 |
1980年 | 1篇 |
1979年 | 1篇 |
排序方式: 共有448条查询结果,搜索用时 609 毫秒
1.
Magnetic Resonance Enteroclysis 总被引:5,自引:0,他引:5
Nicholas C. Gourtsoyiannis Nickolas Papanikolaou 《Seminars in Ultrasound, CT and MRI》2005,26(4):237-246
MR enteroclysis (MRE) is an emerging technique for the evaluation of small intestinal diseases. Administration of an iso-osmotic water solution through a nasojejunal catheter can guarantee adequate luminal distention, and in combination with ultrafast sequences, such as single shot TSE, true FISP, HASTE and 3D FLASH, results in excellent anatomic demonstration of the small intestine. MR fluoroscopy can be performed during MRE examination to monitor the filling process and might be useful in studying low-grade stenosis or motility related disorders. MRE is a very promising technique for the detection and characterization of involved small bowel segments in patients with Crohn's disease while its diagnostic performance in disclosing lumen narrowing and extramural manifestations and complications of the disease is outstanding. Initial experience shows that MRE is very efficient in the diagnosis of small bowel tumors and can be used in the evaluation of small bowel obstruction. 相似文献
2.
3.
Varveris C Koukourakis M Pissakas G Maris T Karpassitis N Katsenis A Kiparissiadis P Gourtsoyiannis N 《Oncology reports》1994,1(2):445-451
Our analysis presents a group of 86 patients with unresectable colorectal cancer who were treated with radical or palliative external beam radiotherapy from 1979-1990 at the Radiation Oncology Department of Greek Anticancer Institute, St. Savvas Hospital, Athens. The dose applied to the tumor area was 20-50 Gy in 2-6 weeks. A CAT-scan guided boost field portal to the primary tumor bed and immediately adjacent nodes was also used. Irradiation was given with a Co-60 unit or a 6 MeV Linear Accelerator using a two, three or 4-field technique. Complete symptomatic relief was achieved in 90% of patients with rectal bleeding, 63% with pain and 37% with mucous discharge. Although the majority of our patients received a higher than 40Gy radiation dose, we have seen symptomatic relief in up to 90% of patients treated with 20-30 Gy in 2-3 weeks. However, the duration of improvement in symptomatic relief of our patients was better for those who had been given higher doses of radiation therapy. The radiation dose was sufficient to relieve symptoms in 40 patients (46.5%) for more than 12 months and in 20 patients (23.2%) for 8-12 months. 相似文献
4.
Panos K. Prassopoulos Christina A. Giannakopoulou Eleni G. Apostolaki Nickolas Z. Charoulakis Nickolas C. Gourtsoyiannis 《Pediatric radiology》1998,28(8):605-607
Psoas abscess in children, and especially in neonates, is an uncommon condition which is difficult to diagnose clinically.
The US, CT and MR findings of a psoas abscess in a neonate, which extended to the thigh, are reported. Imaging was helpful
in revealing the abnormality, in demonstrating its extension and in determining its nature. The child was treated conservatively
and the abscess resolved, leaving atrophy of the psoas muscle.
Received: 24 June 1997 Accepted: 9 January 1998 相似文献
5.
6.
Raissaki M Hatzidakis AA Prassopoulos P Bakandaki A Vrachassotakis N Vasilakis SJ Gourtsoyiannis NC 《European radiology》2000,10(8):1284-1286
A case of recurrent abdominal wall abscess following percutaneous cholecystostomy (PC) is presented. Transperitoneal PC was
performed in an 82-year-old female with calculous cholecystitis. Symptoms resolved and the catheter was removed 29 days later.
The patient came back 5 months later with a superficial abscess that was drained and 8 months post PC with a fistula discharging
clear fluid. Ultrasonography revealed the tract adjacent to an area of inflammation containing a calculus, whereas CT failed
to depict the stone. Subsequent surgery confirmed US findings. To our knowledge, this is the first report of a dislodged bile
stone following percutaneous cholecystostomy.
Received: 27 August 1999; Revised: 7 December 1999; Accepted: 9 December 1999 相似文献
7.
Nickolas Speeney Kirstyn Marie Kameg Thomas Cline Janene Luther Szpak Brea Bagwell 《Archives of Psychiatric Nursing》2018,32(6):845-849
Background
Undergraduate nursing students may not have the opportunity to assess and intervene with a patient diagnosed with schizophrenia during their clinical rotation. Provision of a standardized patient simulation experience affords students this opportunity in a safe setting without risk to the patient or student.Methods
A quasi-experimental design was utilized to explore the impact of the addition of a standardized patient simulation scenario depicting a patient with a diagnosis of schizophrenia on undergraduate nursing student knowledge and perceived competency.Results
The mean values for perceived competence and knowledge increased significantly over the three time periods (p?<?0.001).Conclusion
The results suggest that incorporating SP simulation into the undergraduate psychiatric mental health nursing course has the potential to enhance both knowledge and perceived competency of students in caring for patients diagnosed with schizophrenia and ultimately promote better healthcare outcomes. 相似文献8.
Yuchen Jiao Laura D. Wood Isaac Kinde Jian Wu Nils Mandahl Jinyong Luo Ralph H. Hruban Luis A. Diaz Jr. Tong‐Chuan He Bert Vogelstein Kenneth W. Kinzler Fredrik Mertens Nickolas Papadopoulos 《Genes, chromosomes & cancer》2014,53(1):15-24
Bone and soft tissue sarcomas are a group of histologically heterogeneous and relatively uncommon tumors. To explore their genetic origins, we sequenced the exomes of 13 osteosarcomas, eight myxoid liposarcomas (MLPS), and seven synovial sarcomas (SYN). These tumors had few genetic alterations (median of 10.8). Nevertheless, clear examples of driver gene mutations were observed, including canonical mutations in TP53, PIK3CA, SETD2, AKT1, and subclonal mutation in FBXW7. Of particular interest were mutations in H3F3A, encoding the variant histone H3.3. Mutations in this gene have only been previously observed in gliomas. Loss of heterozygosity of exomic regions was extensive in osteosarcomas but rare in SYN and MLPS. These results provide intriguing nucleotide‐level information on these relatively uncommon neoplasms and highlight pathways that help explain their pathogenesis. © 2013 Wiley Periodicals, Inc. 相似文献
9.
Although the popularity of including figural fluency tests in cognitive and neuropsychological test batteries has increased in recent years, the spontaneous use of strategies on these measures remains poorly understood. This study addressed three questions pertaining to strategy use on the Ruff Figural Fluency Test (RFFT): (i) how common is strategy use, (ii) what information does strategy use convey, and (iii) can examinees learn to use strategies. Findings revealed that nearly seven out of 10 healthy college students used a strategy at least once while taking the RFFT. The number of strategies used and the number of figures produced using a strategy had modest correlations with select executive function measures (D-KEFS Tower Test, Sorting, and Letter & Category Verbal Fluency) in hypothesized directions. When strategies were demonstrated for subjects who did not spontaneously use them, those subjects were able to subsequently use strategies. These findings suggest that although common, failure to spontaneously use a strategy is not unusual. Further, strategy use may reflect a cognitive asset, particularly regarding planning, reasoning, and cognitive flexibility. 相似文献
10.
Gazi Huri Ömer Sunkar Biçer Levent Özgözen Yurdanur Uçar Nickolas G. Garbis Yoon Suk Hyun 《Foot and Ankle Surgery》2013,19(4):261-266
BackgroundMinimally invasive Q3 repair has been proposed for acute Achilles tendon rupture with low rate of complications. However there are still controversies about optimal technique. In this study we aimed to describe Endobutton-assisted modified Bunnell configuration as a new Achilles tendon repair technique and evaluate its biomechanical properties comparing with native tendon and Krackow technique.Methods27 ovine Achilles tendons were obtained and randomly placed into 3 groups with 9 specimens ineach. The Achilles tendons were repaired with Endobutton-assisted modified Bunnell technique in group 1, Krackow suture technique in group 2 and group 3 was defined as the control group including native tendons. Unidirectional tensile loading to failure was performed at 25 mm/min. Biomechanicalproperties such as peak force to failure (N), stress at peak (MPa), elongation at failure, and Young'smodulus (GPa) was measured for each group. All groups were compared with each other using one-wayANOVA followed by the Tukey HSD multiple comparison test (a = 0.05).ResultsThe average peak force (N) to failure of group 1 and group 2 and control group was 415.6 ± 57.6, 268.1 ± 65.2 and 704.5 ± 85.8, respectively. There was no statistically significant difference between native tendon and group 1 for the amount elongation at failure (p > 0.05).ConclusionsRegarding the results, we concluded that Endobutton-assisted modified Bunnell technique provides stronger fixation than conventional techniques. It may allow early range of motion and can be easily applied in minimally invasive and percutaneous methods particularly for cases with poor quality tendon at the distal part of rupture.Level of evidenceLevel II, Biomechanical research study. 相似文献