全文获取类型
收费全文 | 2601篇 |
免费 | 112篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 44篇 |
妇产科学 | 40篇 |
基础医学 | 229篇 |
口腔科学 | 51篇 |
临床医学 | 191篇 |
内科学 | 591篇 |
皮肤病学 | 44篇 |
神经病学 | 240篇 |
特种医学 | 131篇 |
外科学 | 447篇 |
综合类 | 11篇 |
一般理论 | 1篇 |
预防医学 | 33篇 |
眼科学 | 88篇 |
药学 | 105篇 |
中国医学 | 1篇 |
肿瘤学 | 461篇 |
出版年
2023年 | 11篇 |
2022年 | 27篇 |
2021年 | 38篇 |
2020年 | 22篇 |
2019年 | 31篇 |
2018年 | 37篇 |
2017年 | 34篇 |
2016年 | 61篇 |
2015年 | 71篇 |
2014年 | 75篇 |
2013年 | 99篇 |
2012年 | 133篇 |
2011年 | 155篇 |
2010年 | 96篇 |
2009年 | 78篇 |
2008年 | 144篇 |
2007年 | 120篇 |
2006年 | 161篇 |
2005年 | 124篇 |
2004年 | 144篇 |
2003年 | 131篇 |
2002年 | 137篇 |
2001年 | 90篇 |
2000年 | 75篇 |
1999年 | 64篇 |
1998年 | 33篇 |
1997年 | 32篇 |
1996年 | 44篇 |
1995年 | 28篇 |
1994年 | 35篇 |
1993年 | 24篇 |
1992年 | 50篇 |
1991年 | 33篇 |
1990年 | 28篇 |
1989年 | 41篇 |
1988年 | 24篇 |
1987年 | 31篇 |
1986年 | 31篇 |
1985年 | 23篇 |
1984年 | 12篇 |
1983年 | 12篇 |
1981年 | 6篇 |
1980年 | 5篇 |
1979年 | 10篇 |
1975年 | 4篇 |
1974年 | 7篇 |
1973年 | 7篇 |
1972年 | 8篇 |
1971年 | 4篇 |
1969年 | 4篇 |
排序方式: 共有2716条查询结果,搜索用时 31 毫秒
1.
Laparoscopic cholecystectomy and time-course changes in renal function 总被引:13,自引:3,他引:10
Y. Miki K. Iwase W. Kamiike E. Taniguchi K. Sakaguchi J. Sumimura H. Matsuda I. Nagai 《Surgical endoscopy》1997,11(8):838-841
Background: Recently, the retraction method has been used to reduce intraabdominal pressure (IAP) during laparoscopic surgery. The purpose
of this study was to determine the serial changes in renal function during laparoscopic cholecystectomy (LC) using the retraction
method.
Methods: Urine output, effective renal plasma flow (ERPF), and glomerular filtration rate (GFR) were measured serially in seven patients
who underwent LC with 12 mmHg pneumoperitoneum (High-IAP group) and five who underwent LC using the retraction method with
4 mmHg pneumoperitoneum (Low-IAP group).
Results: Urine output, ERPF, and GFR were decreased during pneumoperitoneum in the High-IAP group, whereas no significant changes
in any of these parameters were observed in the Low-IAP group.
Conclusions: Our findings demonstrate that reduction of IAP to 4 mmHg using the retraction method prevents the transient renal dysfunction
caused by prolonged 12 mmHg pneumoperitoneum during LC, suggesting that the retraction method reduces the risk of perioperative
renal dysfunction during laparoscopic surgery.
Received: 26 March 1996/Accepted: 27 July 1996 相似文献
2.
3.
4.
Attenuation of lung injury in allograft rejection using NF-kappaB decoy transfection-novel strategy for use in lung transplantation. 总被引:5,自引:0,他引:5
5.
Masujiro Makita MD Futoshi Akiyama MD Naoya Gomi MD Takuji Iwase MD Fujio Kasumi MD Goi Sakamoto MD 《The breast journal》2006,12(S2):S210-S217
Abstract: To improve the utility of mammary ductoscopy, we investigated the correlation between endoscopic findings and histologic findings using intraductal biopsy specimens. Seventy-one intraductal biopsy specimens obtained from 63 patients between October 2001 and March 2004 were analyzed retrospectively. All specimens were obtained from monotonous intraductal lesions immediately after observation by mammary ductoscopy and were composed of a pure histologic subtype. With regard to endoscopic findings, color was classified as yellow, red, white, or colorless, and morphology was classified as spherical, lobular, mulberry, or amorphous. The histologic subtype was classified as papillotubular, papillary, degenerated, papillary cancer, solid-type ductal carcinoma in situ (DCIS), or cribriform cancer. The relationship between histologic diagnosis, color, and morphology was investigated. Intraductal biopsy specimens included 25 specimens of carcinoma and 46 specimens of papilloma. There was no significant correlation between color and diagnosis. Fourteen of 25 carcinoma specimens were amorphous, and amorphous morphology was significantly suggestive of malignancy (p < 0.001). Further, cribriform cancer was associated with amorphous morphology and yellow color. Morphology may be a useful endoscopically delineated parameter for differentiating intraductal lesions. 相似文献
6.
Mitsunori Murata M.D. 《Pediatrics international》1992,34(2):236-242
Since the end of the 2nd World War, Japan has seen quite rapid socioeconomical development. With this development the physical size of Japanese children has increased, but the final size, especially the stature, is still shorter than that of Americans or Europeans. Bone maturation velocities were compared among Japanese and Chinese children and adolescents aged 7 to 18 (in 1986) and English TW2-subjects, using the TW2 method. Asian children and adolescents may have a different tempo of skeletal maturation during pubertal growth from that of English children and adolescents. This, probably genetic, difference in the tempo of skeletal maturation, especially that of RUS, between Japanese and English during pubertal growth may be one of the main causes of the final difference in the stature of the two groups. 相似文献
7.
Hideto SAKAI Kiichiro JINDE Noboru SAOTOME Wei SUNG Mitsunori YAGAME Yasuo NOMOTO Masanobu MIYAZAKI Takashi HARADA 《Nephrology (Carlton, Vic.)》1997,3(1):91-94
Summary: In situ hybridization of mRNA for collagen IV, collagen VI, stromelysin (MMP-3) and TIMP1 was examined in renal biopsy specimens from patients with IgA nephropathy (IgAN) or diabetic nephropathy with various degrees of tissue damage. The majority of cells in the glomeruli expressed these mRNA almost simultaneously, but a few cells demonstrated positive expression for only one of these probes. There was a parallel relationship between the degree of tissue damage and that of mRNA expressions of these probes in patients with IgAN, while patients with diabetic nephropathy showed a reverse relationship between these two parameters. It is concluded that patients with mesangial proliferative glomerulonephritis expressed mRNA for collagen collagenase and its inhibitor in the glomeruli in parallel with the progress of tissue damage. In contrast, glomerular samples from patients with diabetic nephropathy showed that there was an inverse relationship between tissue damage and expression of mRNA. It is concluded that expression of collagen, collagenase and its inhibitor parallels the progression of glomerular changes in IgAN, but such parallel expression was not observed in patients with diabetic nephropathy. 相似文献
8.
9.
A Yasuhara A Hori T Sugimoto S Iwase Y Kobayashi 《Electroencephalography and clinical neurophysiology》1987,67(6):584-587
Photo-evoked eyelid microvibration (PEMV) was recorded in neonates with intracranial hemorrhage in order to determine whether it serves as a useful indicator of clinical course and also prognosis. Although the latency of PEMV was prolonged or absent in the acute stage of ICH, it returned to a normal range in these subjects with the improvement of symptoms. Three infants whose PEMV were still prolonged in the convalescent stage developed mental retardation or cerebral palsy. PEMV may be a useful predictor of the prognosis of neonatal ICH and its prolongation may signal later neurological sequelae. 相似文献
10.
A case-control study of breast cancer among Japanese women: with special reference to family history and reproductive and dietary factors 总被引:8,自引:0,他引:8
Dr. Ikuko Kato Dr. Shigeto Miura Fijio Kasumi Takuji Iwase Hideya Tashiro Yoshihiro Fujita Hiroki Koyama Tadashi Ikeda Kiyoshi Fujiwara Keiichi Saotome Kazuaki Asaishi Rikiya Abe Mitsuhiro Nihei Tsunehiro Ishida Takao Yokoe Hiroshi Yamamoto Motoi Murata 《Breast cancer research and treatment》1992,24(1):51-59
Summary To study the effects of family history and reproductive, anthropometric, and dietary factors on the risk of breast cancer among low risk populations, we conducted a hospital-based case-control study involving 908 patients with breast cancer and their matched controls, in Japan. A positive family history of breast cancer significantly increased the risk of breast cancer (odds ratio = 1.52, 95% confidence interval: 1.14–2.03). The risk further increased with increasing number of family members affected. Obesity, single marital status, fewer births, a late childbirth, and less consumption of green-yellow vegetables and dairy products were also associated with an increased risk of breast cancer. These associations were independent in multivariate analyses. There was no increase in risk associated with consumption of high fat foods. When analyzed by menopausal status, the association with family history of breast cancer, especially in the first degree of relatives, was more evident for premenopausal breast cancer. The associations with obesity and lower consumption of dairy products were more pronounced for postmenopausal breast cancer, while those with lower parity and single marital status were stronger for premenopausal breast cancer. 相似文献