全文获取类型
收费全文 | 2566篇 |
免费 | 283篇 |
国内免费 | 58篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 53篇 |
妇产科学 | 61篇 |
基础医学 | 251篇 |
口腔科学 | 42篇 |
临床医学 | 315篇 |
内科学 | 353篇 |
皮肤病学 | 72篇 |
神经病学 | 128篇 |
特种医学 | 131篇 |
外科学 | 330篇 |
综合类 | 359篇 |
预防医学 | 320篇 |
眼科学 | 22篇 |
药学 | 213篇 |
2篇 | |
中国医学 | 92篇 |
肿瘤学 | 152篇 |
出版年
2024年 | 9篇 |
2023年 | 24篇 |
2022年 | 40篇 |
2021年 | 74篇 |
2020年 | 47篇 |
2019年 | 46篇 |
2018年 | 52篇 |
2017年 | 55篇 |
2016年 | 52篇 |
2015年 | 99篇 |
2014年 | 80篇 |
2013年 | 131篇 |
2012年 | 173篇 |
2011年 | 187篇 |
2010年 | 135篇 |
2009年 | 129篇 |
2008年 | 126篇 |
2007年 | 124篇 |
2006年 | 123篇 |
2005年 | 125篇 |
2004年 | 80篇 |
2003年 | 88篇 |
2002年 | 76篇 |
2001年 | 64篇 |
2000年 | 54篇 |
1999年 | 56篇 |
1998年 | 38篇 |
1997年 | 34篇 |
1996年 | 20篇 |
1995年 | 30篇 |
1994年 | 18篇 |
1993年 | 33篇 |
1992年 | 36篇 |
1991年 | 41篇 |
1990年 | 27篇 |
1989年 | 31篇 |
1988年 | 33篇 |
1987年 | 40篇 |
1986年 | 42篇 |
1985年 | 28篇 |
1984年 | 17篇 |
1983年 | 20篇 |
1982年 | 13篇 |
1980年 | 11篇 |
1979年 | 11篇 |
1978年 | 17篇 |
1977年 | 16篇 |
1976年 | 17篇 |
1974年 | 16篇 |
1973年 | 13篇 |
排序方式: 共有2907条查询结果,搜索用时 0 毫秒
1.
We report a case of left iliofemoral vein thrombosis with extension to the inferior vena cava associated with giant right hydronephrosis secondary to ureteropelvic junction obstruction. Surgery revealed marked infrarenal vena caval compression and deviation to the left side caused by the dilated right renal pelvis, with resultant kinking of the origin of the left iliac vein. It is postulated that the reduction in blood flow caused by this compression and distortion predisposed this patient to venous thrombosis. 相似文献
2.
3.
The CXC chemokine stromal cell-derived factor 1 is not responsible for CD8+ T cell suppression of syncytia-inducing strains of HIV-1
下载免费PDF全文
![点击此处可从《Proceedings of the National Academy of Sciences of the United States of America》网站下载免费的PDF全文](/ch/ext_images/free.gif)
4.
Joyce J. Fitzpatrick Sheila Ryan DeWitt Baldwin Roger Bulger Jean Johnson-Pawlson Christopher McLaughlin Maureen Kelley Leopold Selketr Bernardine Lacey Charlene Hanson Robin Harvan Patricia Hinton Walker David Sluyter Mary Joan Ladden Neal Vanselow 《Journal of Midwifery & Women's Health》1998,43(1):61-65
In 1995, the National League for Nursing commissioned a Panel on Interdisciplinary/Transdisciplinary Education. The focus of the Panel's work was to examine educational issues that transcend the health professions and to make recommendations for future implementation of an interdisciplinary approach to addressing them. This article is being simultaneously published by several professional journals. The goal is to seek as much feedback as possible. 相似文献
5.
E Anne Lacey R June Musgrave Jenny V Freeman Angela M Tod Peter Scott 《European Journal of Cardiovascular Nursing》2004,3(3):219-224
BACKGROUND: Psychological morbidity after an acute myocardial infarction (AMI) is known to be common, but can be addressed by appropriate rehabilitation. The area in which this research was conducted experiences high rates of deprivation and of coronary heart disease and limited access to hospital-based rehabilitation. Responding to concern about psychological needs of AMI patients, a self-help package was introduced and evaluated alongside standard hospital-based cardiac rehabilitation. AIMS: To evaluate the impact of a home-based self-help package (the Heart Manual), alongside existing cardiac rehabilitation provision, on psychological morbidity and health status after AMI. A secondary aim was to assess the suitability of the Heart Manual for older patients aged over 80 years. METHODS: A controlled observational study, comparing two cohorts of patients discharged from hospital after AMI. The intervention group was given the self-help package in addition to standard care. The control group received standard care alone. Outcome measures used were the Hospital Anxiety and Depression Scale and the EuroQol. RESULTS: The intervention group showed significant improvement in anxiety and depression scores after 3 months and nonsignificant improvement in general health status. Patients who attended hospital-based rehabilitation classes, and those aged over 80 years, also benefited from the intervention. CONCLUSION: A home-based self-help rehabilitation package is an effective tool alongside hospital-based rehabilitation classes and can be given to all age groups. 相似文献
6.
Bayrak S; Holmdahl R; Travers P; Lauster R; Hesse M; Dolling R; Mitchison NA 《International immunology》1997,9(11):1687-1699
Type II collagen (CII) is of immunological interest because of its
repetitive structure and properties as an autoantigen. The mouse gene has
recently been cloned, thus enabling T cell-defined epitopes to be
identified. Multiple novel epitopes on mouse CII are here detected in the
autoreactive T cell response. The major response is directed to an epitope
with residues 707-721 located on the CB10 fragment. Some 25 other epitopes
are also recognized, including the autologous homologue of the 256-270
epitope which dominates in the response to foreign collagen. The cells
reactive with mouse collagen peptides were of Th1 type, as judged by
release of IFN-gamma. No significant reactivity was detected to mouse CII
peptides during ongoing disease. Alignment of the mouse epitopes revealed a
sequence motif with characteristic side chains at residues P1, P4 and P7,
and to a lesser extent at P5, within a nonamer core sequence. Binding of
these epitopes was simulated in a computer model of the I-Aq molecule,
where peptides with anchor residues at P1, P4 and P7 were indeed found to
fit the binding groove best. The spacing of pockets and the fine structure
of the binding surface of the I-Aq molecule meshes with the repetitive
structure of the collagen (X-Y-Gly), thus providing a likely explanation
for the occurrence of multiple epitopes. Comparison with human DR binding
motifs showed that the I-Aq motif resembles most closely that of the DR4
subtypes which predispose for rheumatoid arthritis.
相似文献
7.
8.
Modified extravesical ureteral reimplantation in pediatric renal transplantation: 5 years of experience. 总被引:1,自引:0,他引:1
H G Mesrobian C G Miller R L Hatchett R G Azizkhan S R Lacey 《The Journal of urology》1992,147(5):1340-1342
Numerous surgical procedures have been described to reimplant the ureter into the bladder during renal transplantation. Since November 1985 we have used a modified extravesical technique in 19 children. At the time of transplantation patient age ranged from 2 to 17 years (average age 10 years). Of these patients only 2 received a cadaveric kidney. Postoperative followup ranged from 4 to 54 months (average 32 months). No immediate or delayed urological complications were noted, and all but 1 graft has continued to function. This procedure is not only expeditious and safe but it also eliminates a long cystostomy suture line and requires a short ureteral length. Urinary leakage and ureteral obstruction, 2 of the most common urological complications, have not been observed in our patients. Although further experience and longer followup are required, this technique has become our procedure of choice for ureteral reimplantation in children undergoing renal transplantation. 相似文献
9.
10.
北方汉族人群维生素D受体基因Bsm I位点多态性与前列腺癌易感性的相关性分析 总被引:1,自引:1,他引:0
目的 :研究低发病的中国汉族人群维生素D受体基因 (VDRG)BsmⅠ 位点单核苷酸多态性 (SNP)与前列腺癌的关系 ,探讨不同种族前列腺癌发病的基因差异。 方法 :收集中国北方地区汉族人群 10 3例前列腺癌病人及10 6例健康对照者外周血标本 ,应用变性高效液相色谱 (DHPLC)检测VDRG第 8内含子BsmⅠ多态位点 ,并对该位点SNP分布进行分析。 结果 :BsmⅠ 多态位点bb、Bb、BB基因型和等位基因在北方地区汉族前列腺癌病人及对照者中的分布频率差异无显著性 (P >0 .0 5 ) ,基因型分布频率分别为 92 .2 3%、7.77%、0和 94.34 %、5 .6 6 %、0 ;等位基因B、b分别为 3.88%、96 .12 %和 2 .91%、97.0 9%,而与高发病人群的分布相比有显著不同。 结论 :VDRGBsmⅠ多态性在低发病的中国汉族人群与前列腺癌无相关 ,其分布与高发病人群有明显差异 ,提示VDRGBsmⅠ多态性可能是前列腺癌发病种族差异的原因之一。 相似文献