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排序方式: 共有127条查询结果,搜索用时 15 毫秒
1.
Gaspare Palaia Alessandra Impellizzeri Gianluca Tenore Federico Caporali Paolo Visca Alessandro Del Vecchio Gabriella Galluccio Antonella Polimeni Umberto Romeo 《Clinical oral investigations》2020,24(8):2645-2652
The aim of this study was to evaluate, ex vivo, the histological effects of 445-nm diode laser (Eltech K-Laser srl, Treviso, Italy), during an oral soft ti 相似文献
2.
Palaia DA Rosenberg MH Bonanno PC DeChiara SC Petro JA 《Facial plastic surgery : FPS》2001,17(1):57-66
On a path analogous to other surgical disciplines, the progression of facial cosmetic surgery has trended toward shorter scars and less invasive techniques. This article outlines an approach to facelifting that limits the scar to the temporal scalp, preauricular area, and retroauricular sulcus. It will enable the reader to identify those patients who are candidates for a less invasive procedure compared with the conventional facelift approach. Specifically, the temporal facelift addresses the lateral brow, the middle one third of the face, and the upper neck. In addition, this article examines the various and current methods for treatment of the glabellar area of the forehead. Medical and surgical options are outlined for the correction of those rhytids induced by corrugator and procerus muscle activity. 相似文献
3.
Aldo Quattrone MD Antonio Bagnato MD Grazia Annesi PhD Fabiana Novellino MD Letterio Morgante MD Giovanni Savettieri MD Mario Zappia MD Patrizia Tarantino PhD Innocenza Claudia Cirò Candiano PhD Ferdinanda Annesi PhD Donatella Civitelli PhD Francesca Emanuela Rocca PhD Marco D'Amelio MD Giuseppe Nicoletti MD Maurizio Morelli MD Alfredo Petrone MD Piercostanzo Loizzo MD Francesca Condino PhD 《Movement disorders》2008,23(1):21-27
Myocardial 123Metaiodobenzylguanidine (MIBG) enables the assessment of postganglionic sympathetic cardiac innervation. MIBG uptake is decreased in nearly all patients with Parkinson's disease (PD). Our objective was to evaluate MIBG uptake in patients with genetic PD. We investigated MIBG uptake in 14 patients with PD associated with mutations in different genes (Parkin, DJ‐1, PINK1, and leucine‐rich repeat kinase 2 ‐LRRK2), in 15 patients with idiopathic PD, and 10 control subjects. The myocardial MIGB uptake was preserved in 3 of the 4 Parkin‐associated Parkinsonisms, in 1 of the 2 patients with DJ‐1 mutations, in 1 of the 2 brothers with PINK1 mutations, in 3 of the 6 unrelated patients with Gly2019Ser mutation in the LRRK2 gene, whereas it was impaired in all patients with idiopathic PD. MIBG was preserved in all control subjects. Our study shows that myocardial MIGB uptake was normal in 8 of 14 patients with genetic PD, suggesting that cardiac sympathetic denervation occurs less frequently in genetic PD than in idiopathic PD. Our findings also demonstrate that MIGB uptake has a heterogeneous pattern in genetic PD, because it was differently impaired in patients with different mutations in the same gene or with the same gene mutation. © 2007 Movement Disorder Society 相似文献
4.
Umberto Romeo Gaspare Palaia Ricciarda Botti Valentina Leone Jean-Paul Rocca Antonella Polimeni 《Lasers in medical science》2010,25(6):891-899
As the American Academy of Periodontology indicates, the treatment of chronic periodontitis should be achieved in the least
invasive manner through non-surgical periodontal therapy. However, complete removal of subgingival plaque and calculus is
hindered with increasing probing depth (PD) and furcation involvement using hand, sonic or ultrasonic instruments. Many authors
have suggested that the use of laser as an adjunct to scaling and root planing (SRP) might improve the effectiveness of conventional
periodontal treatment. The aim of this study was to evaluate potassium–titanyl–phosphate (KTP) laser in non-surgical periodontal
therapy. Seven hundred and thirty sites with probing depths of 4–6 mm were involved in the study. The sites were divided into
four groups: control (SRP, chlorhexidine gel 0.5%), group A (SRP, chlorhexidine gel 0.5%, three sessions of KTP laser irradiation);
group B (SRP, three sessions of KTP laser irradiation) and group C (SRP, irrigation with povidone-iodine 10%, three sessions
of KTP laser irradiation). KTP laser was used with the following parameters: output power 0.6 W, time on 10 ms, time off 50 ms,
30 s per irradiation, fluence 19 J/cm2. All the sites showed improvement in all clinical parameters. Clinical attachment loss (CAL), pocket probing depths (PPDs)
and bleeding on probing (BOP), especially in the lased groups, showed significant results (P < 0.001). Our experience showed KTP laser to be a significant help in SRP; nevertheless, more studies are necessary to confirm
our results. 相似文献
5.
ObjectivesThe Peripheral Giant Cell Granuloma (PGCG) is a gingival hyperplasia that rises from the mucoperiostium or the periodontal ligament and may occur at gingival edges or alveolar ridges of the oral mucosa. In this paper a case of PGCG treated by a diode laser 808 nm is described.Materials and methodsA case of a 65 years old female patient, in good health, with a PGCG located at the anterior portion of edentulous maxilla, is described. The mass was surgically excised using an 808 nm diode laser (KDL-10, Kavo, Germany) with parameters of 2 W continuous wave and a 320 nm optic fiber.ResultsSurgery was performed with no intra- nor post-operative complications. Follow-up at 7 and 21 days showed an increasing secondary intention healing. Histological examination confirmed the clinical diagnosis of peripheral giant cell granuloma.ConclusionsLaser surgery of PGCG offers many intraoperative advantages and reduces postoperative complications, also increasing patient's compliance. For that reason, as well as in light of recent literature studies, it may be considered as the gold standard. 相似文献
6.
Aquilani R La Rovere MT Febo O Baiardi P Boschi F Iadarola P Viglio S Dossena M Bongiorno AI Pastoris O Verri M 《Nutrition (Burbank, Los Angeles County, Calif.)》2012,28(10):1002-1007
ObjectiveThe proteins in the lungs are in constant flux, undergoing degradation and resynthesis. We investigated pulmonary protein and amino acid metabolism, the biochemical basis of the remodeling process, in individuals with chronic heart failure receiving or not receiving β-blocker therapy with bisoprolol (BIS).MethodsClinically stable rehabilitative patients with chronic heart failure, without metabolic diseases or liver/renal failure, and with a stable weight over the preceding 3 mo underwent right heart catheterization, and radial artery cannulation. Mixed central venous and arterial blood samples were drawn simultaneously to calculate the venous-arterial difference of amino acids (pulmonary uptake and release).ResultsTwenty-two patients on BIS therapy and eight not receiving BIS were analyzed. The two groups showed a net pulmonary protein synthesis (i.e., a positive value of phenylalanine [venous-arterial difference] × cardiac index product) and amino acid extraction, the rates of which were significantly lower in patients on BIS therapy. The two groups had pulmonary hypertension (mean pulmonary artery pressure >19 mmHg). Pulmonary vascular resistance was 57% higher in patients not receiving BIS than in those on BIS therapy (6.65 ± 2.90 versus 4.23 ± 1.49 mmHg/L · min?1 · m?2, P < 0.05). Pulmonary vascular resistance correlated positively with the pulmonary extraction of total essential amino acids (r = +0.4576, P = 0.01) and leucine (r = +0.5083, P = 0.004), the most important amino acid for protein synthesis.ConclusionPatients with chronic heart failure have increased rates of amino acid extraction and pulmonary protein synthesis, suggesting, at least in part, an increased rate of lung remodeling. Therapy with BIS attenuates lung metabolic abnormalities. 相似文献
7.
Romeo U Libotte F Palaia G Del Vecchio A Tenore G Visca P Nammour S Polimeni A 《Lasers in medical science》2012,27(4):749-753
In oral pathology, laser devices can provide important advantages, especially in the treatment of certain lesions. However, there is controversy about the use of some wavelengths in the analysis of suspected dysplastic or neoplastic lesions, raising doubt about the laser's suitability for use in biopsy procedures. In recent studies, the KTP and diode lasers have been used in biopsy procedures without histological artefacts. The aim of this in vitro study was to evaluate the exact extent of peripheral thermal damage to oral soft tissues caused by an Er:YAG laser (λ 2,940 nm) without water cooling. The study was performed on five swine cadaver tongues. Nine samples from each tongue were taken by the same operator using the Er:YAG laser with increasing energies (from 60 to 150 mJ) and fluencies (from 21 to 53 J/cm(2)). In addition to the laser samples, a specimen obtained using a scalpel was used as control. The samples were placed in 10% formalin solution and were examined by optical microscopy by two blinded pathologists who assigned a thermal damage score (from 0 to 3) to each sample. The Er:YAG laser produced less damage at 80 and 100 mJ and 28 and 35 J/cm(2) (intermediate parameters). Although in some samples thermal damage was minimally visible, in all samples histological evaluation was clearly possible. The study demonstrated that the Er:YAG laser can be safely used in oral biopsy investigations while ensuring a successful histological evaluation, which is fundamental to correct clinical management. 相似文献
8.
9.
Zullo MA Plotti F Calcagno M Marullo E Palaia I Bellati F Basile S Muzii L Angioli R Panici PB 《European urology》2007,51(5):1376-82; discussion 1383-4
OBJECTIVES: To compare tension-free vaginal tape (TVT) and trans-obturator suburethral tape from inside to outside (TVT-O) for surgical treatment of stress urinary incontinence (SUI) for complications (primary end point) and success rate (secondary end point). METHODS: Seventy-two consecutive patients, with a mean age of 53.2 yr (range: 38-69 yr) and affected by SUI, were included in this randomised controlled trial. After preoperative assessment, patients were randomly allocated to the TVT or TVT-O procedure. Operative time, perioperative complications, and hospital stay were prospectively recorded. Cure of SUI was defined as no leakage of urine during the stress test at urodynamic testing at the 12-mo evaluation. The Wilcoxon signed rank sum test, Mann-Whitney U test, McNemar test, and Fisher exact test were used to verify statistical significance, set at p<0.05. RESULTS: All patients were evaluable at the 12-mo follow-up. The characteristics of patients were well balanced between groups after randomisation. The mean operative time was significantly shorter in the TVT-O group. Perioperative complications were significantly more common after the retropubic approach (5% and 27% in TVT-O and TVT groups, respectively, p<0.04). The groups did not differ significantly in intraoperative blood loss, hospital stays, and time to return to normal activities. Sixty-five patients (90%) were successfully treated for SUI 12 mo after the operation (89% and 91% for TVT-O and TVT groups, respectively). CONCLUSIONS: Both techniques appear to be equally effective in the surgical treatment of SUI. However, TVT-O had a shorter operative time and lower overall perioperative complication rate. 相似文献
10.
C Marchetti L Imperiale ML Gasparri I Palaia S Pignata T Boni F Bellati P Benedetti Panici 《Expert opinion on investigational drugs》2012,21(10):1575-1584
Introduction: Ovarian cancer is the most important cause of gynecological cancer-related mortality. Conventional treatments for advanced or recurrent disease offer limited results in terms of long-term responses and survival. Researches have recently focused on target therapies, which represent a new, promising, therapeutic approach, able to maximizing tumor kill and minimizing toxicity. The family of polyadenosine diphosphate-ribose polymerase (PARP) inhibitors is currently one of the most hopeful and investigated alternatives. Areas covered: Preclinical and clinical studies of Olaparib , the most investigated PARP inhibitor in ovarian cancer, are analyzed and discussed. Data were obtained by searching for all English peer-reviewed articles on Medline, on Cochrane Database and all on-going Phase I and II studies registered on National Cancer Institute Clinical Trials; also any related abstracts recently presented on Olaparib at major international congresses will be included. Expert opinion: Bad prognosis and drug resistance usually affect ovarian cancer. Recent trends toward the knowledge of molecular-specific pathways have produced new target drugs. PARP inhibition mediated by Olaparib in BRCA1 (breast cancer 1) and BRCA2 (breast cancer 2)-mutated and in sporadic ovarian cancer represents a promising field of investigation. Further studies are needed to confirm initial exciting results. 相似文献