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Single‐day sodium picosulfate and magnesium citrate versus split‐dose polyethylene glycol for bowel cleansing prior to colonoscopy: A prospective randomized endoscopist‐blinded trial 
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In vitro assessment of knee MRI in the presence of metal implants comparing MAVRIC‐SL and conventional fast spin echo sequences at 1.5 and 3 T field strength 下载免费PDF全文
下载免费PDF全文 Hans Liebl MD Ursula Heilmeier MD Sonia Lee MD Lorenzo Nardo MD Janina Patsch MDPHD Christopher Schuppert MS Misung Han PHD Ina‐Christine Rondak Dipl. Stat. Suchandrima Banerjee PHD Kevin Koch PHD Thomas M. Link MD PHD Roland Krug PHD 《Journal of magnetic resonance imaging : JMRI》2015,41(5):1291-1299
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Matthias M. Heck Michael Souvatzoglou Margitta Retz Roman Nawroth Hubert Kübler Tobias Maurer Mark Thalgott Bettina M. Gramer Gregor Weirich Ina-Christine Rondak Ernst J. Rummeny Markus Schwaiger Jürgen E. Gschwend Bernd Krause Matthias Eiber 《European journal of nuclear medicine and molecular imaging》2014,41(4):694-701
Purpose
The aim of this study was to prospectively compare diffusion-weighted magnetic resonance imaging (DWI) and [11C]choline positron emission tomography/computed tomography (PET/CT) with computed tomography (CT) for preoperative lymph node (LN) staging in prostate cancer (PCa) patients.Methods
Between June 2010 and May 2012, CT, DWI and [11C]choline PET/CT were performed preoperatively in 33 intermediate- and high-risk PCa patients undergoing radical prostatectomy (RP) and extended pelvic lymph node dissection (ePLND) including obturator fossa and internal, external and common iliac fields. Patient- and field-based performance characteristics for all three imaging techniques based on histopathological results are reported. Imaging techniques were compared by means of the area under the curve (AUC).Results
LN metastases were detected in 92 of 1,012 (9 %) LNs from 14 of 33 (42 %) patients. On patient-based analysis, sensitivity, specificity and accuracy for CT were 57, 68 and 64 %, respectively, for DWI were 57, 79 and 70 %, respectively, and for [11C]choline PET/CT were 57, 90 and 76 %, respectively. On field-based analysis, these numbers for CT were 47, 94 and 88 %, respectively, for DWI were 56, 97 and 92 %, respectively, and for [11C]choline PET/CT were 62, 96 and 92 %, respectively. Neither DWI nor [11C]choline PET/CT performed significantly better than CT on pairwise comparison of patient- and field-based results.Conclusion
All three imaging techniques exhibit a rather low sensitivity with less than two thirds of LN metastases being detected on patient- and field-based analysis. Overall diagnostic efficacy did not differ significantly between imaging techniques, whereas distinct performance characteristics, esp. patient-based specificity, were best for [11C]choline PET/CT followed by DWI and CT. 相似文献
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