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排序方式: 共有3323条查询结果,搜索用时 31 毫秒
1.
Mallet K-N Tuekpe Hidemi Todoriki Satoshi Sasaki Kui-Cheng Zheng Makoto Ariizumi 《Hypertension research》2006,29(6):389-396
Potassium, which is abundant in vegetables, is inversely related to blood pressure. Although the situation has changed somewhat in recent years, the Okinawan diet has generally included a large amount of vegetables, and until recently Okinawans had the lowest rates of mortality due to stroke and coronary heart disease in Japan. Based on the hypothesis that these low mortality rates are partly attributable to increased potassium intake resulting from the high vegetable consumption, this study examined whether increasing the consumption of typical yellow-green Okinawan vegetables increases potassium intake. The purpose of this investigation was to determine whether increased consumption of these vegetables should be one of the dietary modifications recommended in public health promotion programs for Okinawans. The study employed 56 healthy, normotensive, free-living Japanese women aged 18-38 years living in Okinawa. They were randomized to a dietary intervention group (n=27) or a control group (n=29). Members of the dietary intervention group received an average weight of 371.4 g/day of a combination of the following vegetables twice weekly through an express home parcel deliver service for a period of 14 days: Goya (Momordica charantia), green papaya (Carica papaya), Handama (Gynura bicolor), Karashina (Brassica juncea), Njana (Crepidiastrum lanceolatium), Fuchiba (Artemisia vulgaris) and Fudanso (Beta vulgaris); and they consumed an average of 144.9 g/day, resulting in a 20.5% increase in their urinary potassium excretion over the baseline (p=0.045). The members of the control group were asked to avoid these vegetables, and the change in potassium excretion in this group was not significant (p=0.595). Urinary sodium and magnesium excretions, systolic and diastolic blood pressures, folic acid, triglycerides and serum high density lipoprotein cholesterol, low density lipoprotein cholesterol and total cholesterols changed non-significantly in both groups. Also, post-intervention urinary potassium excretion correlated positively with vegetable consumption in both the dietary intervention (p<0.0001) and control (p=0.008) groups and with Okinawan vegetable intake in the dietary intervention group (p=0.0004). 相似文献
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A Fujino A Ishibashi K Koshiba O Hoshiai S Aiso K Yasuda T Sogo 《Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology》1990,81(1):37-44
Gamma seminoprotein (gamma Sm), a glycoprotein isolated from human seminal plasma with a molecular weight of 29,000 and possibly a serine protease, has been demonstrated to be one of the prostate organ-specific antigens. We established a murine monoclonal antibody (MoAb) to gamma-Sm in order to prove the presence and localization of this protein in the prostate. The hybrid clones were obtained by fusing mouse SP2/O-Ag-14 myeloma cells with splenocytes from Balb/c mouse immunized with the major fractions of gamma-Sm. The enzyme-linked immunosorbent assay was done for antibody screening. After cloning twice in soft agarose, the stable clone, termed 43-21-1-1, was finally chosen. This MoAb, IgG1(kappa), recognized gamma-Sm specifically, which was verified by an immunoblotting assay. The specificity of the MoAb was further evaluated by immunohistochemical study by the avidin biotin complex method. Periodate-lysine-paraformaldehyde-fixed surgical specimens, including the prostate associated with fibromuscular hyperplasia, seminal vesicles, bladder, testis and epididymis, were examined. Formaldehyde (10%)-fixed surgical specimens from patients with adenocarcinoma of the prostate and primary transitional cell carcinoma arising from the periurethral prostatic ducts were also examined. Positive reactions of gamma-Sm were recognized only in the cytoplasm of prostatic glandular epithelial cells and along the luminal surface. Fibrous and muscular tissues always given negative staining. Neither nonprostatic tissues nor transitional cell carcinoma of the prostate were stained positively for gamma-Sm. These results show that this MoAb (43-21-1-1) is quite specific to gamma-Sm and may be useful for the immunohistochemical study with prostatic tissue. 相似文献
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Symptomatic liver cyst: Special reference to surgical management 总被引:2,自引:0,他引:2
Kenji Kakizaki Hidemi Yamauchi Shin Teshima 《Journal of Hepato-Biliary-Pancreatic Surgery》1998,5(2):192-195
We conducted a retrospective study of 14 patients with symptomatic liver cysts to evaluate current therapeutic interventions
for this condition. Abdominal pain (n = 7) or abdominal mass (n = 5) were the most frequent presentations. Three patients also had renal cyst. Percutaneous aspiration with ethanol sclerotheraphy
was carried out in 4 patients and all cysts so treated diminished in size, with relief of the symptoms. One patient was treated
by aspiration only and re-retension occurred. Cystectomy was performed in 2 patients, unroofing in 5, and fenestration in
2 patients. All patients gained relief of symptoms, with no recurrence of symptoms. Computed tomography revealed that the
cysts were diminished or were no longer observable after all the treatments. Our experience indicates that unroofing, fenestration,
and cystectomy are safe and suitable procedures for treatment of the condition. Ethanol sclerotherapy may be a feasible alternative
to surgical intervention in selected patients.
Received for publication on July 23, 1997; accepted on Dec. 25, 1997 相似文献
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Hidemi Yamauchi MD Kikuo Miyagawa Masamitsu Maeda Seiki Matsuno Toshio Sato 《Surgery today》1986,16(1):8-15
The findings in twenty-two patients with insulinoma were reviewed, as continuous efforts should be made to establish preoperative
localization of the tumor. Superselective arteriography and percutaneous, transhepatic portal vein and pancreatic venous catheterization
are highly recommended approaches. At the time of surgical intervention, a cautious exploration of the pancreas after thorough
mobilization is most important. Recent use of intraoperative ultrasonography increases the likelihood of finding these occult
tumors which locate deeply in the head of the pancreas. Apart from the diagnostic problems, we wish to emphasize the high
incidence of malignancy (7/22, 31.8 per cent) in our series. Althout patients with malignant isulinoma had a much better prognosis
compared to those with a pancreatic ductal malignancy, pancreatic resection with regional lymphnode dissection seems to be
a rational procedure. Enucleation can be done when intraoperative findings of the tumor and regional lymphonode indicate no
malignant features and no multiple lesions. However, at the first operation, enucleation is still a procedure of choice, even
for the malignant insulinoma in the head with a well-defined capsule and no metastatic lesions, the objective being to avoid
a duodenopancreatectomy or total pancreatectomy.
These data were reported at the 30th Congress of Société Internationale de Chirurgie, Hamburg, Germany, 1983 相似文献
9.
Takuro Yoshikawa Yasuyuki Suzuki Yasuhiro Fujino Keitaro Kakinoki Shiri Li Tadahiro Goto Tomohiro Tanaka Ippei Matsumoto Tetsuya Sakai Yasuki Tanioka Hiroshi Yokozaki Yoshikazu Kuroda 《American journal of transplantation》2005,5(9):2135-2142
Small bowel transplantation (SBT) is associated with a high incidence of infectious complications because of ischemia/reperfusion (I/R) mucosal injury concomitant with potent immunosuppression. In this study, we evaluated whether the cavitary two-layer method (cTLM) could reduce I/R injury and allow early mucosal restoration, particularly after prolonged preservation and transplantation. Canine heterotopic segmental SBT was performed immediately without preservation (group 1), after 24-h preservation in UW solution (group 2) or by the cTLM (group 3). The graft samples were taken 1 h after reperfusion and on days 1, 4 and 7. We assessed graft mucosa with detailed microscopic and electromicroscopic analyses. In Group 3, histological injury and cell apoptosis after transplantation were significantly alleviated and rapidly recovered to a similar level of group 1. The mucosal restoration was morphologically completed within 4 days. In contrast, in group 2, more pronounced mucosal injury and delayed recovery were noted. Crypt cell proliferation activity was well maintained in groups 1 and 3 throughout the experimental period. Our ultrastructural analysis suggested that mitochondrial integrity achieved by the cTLM was a basal mechanism under the prompt mucosal restoration. The cTLM could reduce I/R injury, facilitate mucosal regeneration and restore the nearly normal structure early after SBT. 相似文献