Wirbelsynostosen

Ohne ZusammenfassungMit 35 Textabbildungen.     

Die nichttuberkulöse Spondylitis

Zusammenfassung Es werden die klinischen und röntgenologischen Besonderheiten der Staphylokokken-, Streptokokken-, Pneumokokken-, Typhus- und Paratyphusbacillenspondylitis besprochen. Sie kommen jetzt häufiger zur Beobachtung.Vor der Überschätzung des Röntgenbildes in der Differentialdiagnose wird gewarnt.Die Differentialdiagnose nichttuberkulöser und tuberkulöser Spondylitis wird besprochen. Sie verlangt eingehende klinische Untersuchung und Beobachtung.Die bessere Prognose, der schnellere Heilverlauf und die einfachere Behandlung der nichttuberkulösen Spondylitis ist hervorzuheben.Abscesse bei nichttuberkulösen Spondyliten müssen frühzeitig operativ eröffnet werden. Bei Lendenwirbelabscessen wird die Abmeißelung der Querfortsätze empfohlen, um den Eiterherd genügend zugänglich zu machen.Mit 20 Textabbildungen.     

A new aspect on the development of chronic middle ear diseases in patients with cleft palate

BACKGROUND: The prevalence of chronic middle ear disease in patients after surgery for cleft palate is about 50%. Aim of the present study was to analyse its morphological and physiological causes to prevent chronic atelectatic otitis media or cholesteatoma. METHODS: 15 adult patients with cleft palate were examined using middle ear microscopy, pure tone audiometry, EMG of the tensor veli palatini muscle and MRI of the Eustachian tube. RESULTS: 8 of 15 patients had chronic middle ear disease. With 13 of 15 patients single motor unit action potentials could be recorded from the tensor veli palatini muscle. MRI of the Eustachian tube revealed two decisive observations in patients with chronic middle ear disease: in 4 patients the pterygoid hamulus could not be detected, in all otitis patients the continuity of tensor veli palatini muscle was interrupted or disturbed by medial or lateral fixation. CONCLUSION: Chronic middle ear disease with cleft palate patients is basically caused by impaired muscular compliance of the Eustachian tube. Thus integrity of hamulus as well as tensor veli palatini muscle must become of crucial interest in cleft palate surgery.     

The human myometrium as a target for melatonin

The circadian timing of spontaneous human deliveries results in births occurring statistically more often during the nocturnal phase of the 24-h cycle. The neuroendocrine mechanisms underlying this physiological phenomenon are not understood. In an effort to test the hypothesis that melatonin may serve as an endocrine signal for coordinating myometrial events in the human, we determined the mRNA expression of both MT1 and MT2 melatonin receptor isoforms in pregnant as well as nonpregnant myometrial biopsies by means of RT-PCR and in situ hybridization histochemistry. Additionally, we could demonstrate specific, high affinity iodomelatonin binding to myometrial tissues of both pregnant and nonpregnant women. Primary cultures of myocytes responded differentially from melatonin in terms of cAMP signaling depending on the reproductive state. These results imply that melatonin may have the potential to modulate myometrial function in the human, a finding that could open up new possibilities for the development of novel therapeutic agents.     

Die Wirbelbogenbrüche

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