收费全文 | 2137篇 |
免费 | 113篇 |
国内免费 | 20篇 |
耳鼻咽喉 | 45篇 |
儿科学 | 120篇 |
妇产科学 | 188篇 |
基础医学 | 203篇 |
口腔科学 | 110篇 |
临床医学 | 171篇 |
内科学 | 466篇 |
皮肤病学 | 41篇 |
神经病学 | 159篇 |
特种医学 | 50篇 |
外科学 | 413篇 |
综合类 | 26篇 |
预防医学 | 46篇 |
眼科学 | 84篇 |
药学 | 82篇 |
中国医学 | 2篇 |
肿瘤学 | 64篇 |
2023年 | 26篇 |
2022年 | 24篇 |
2021年 | 84篇 |
2020年 | 61篇 |
2019年 | 68篇 |
2018年 | 95篇 |
2017年 | 61篇 |
2016年 | 98篇 |
2015年 | 100篇 |
2014年 | 89篇 |
2013年 | 137篇 |
2012年 | 160篇 |
2011年 | 178篇 |
2010年 | 118篇 |
2009年 | 83篇 |
2008年 | 166篇 |
2007年 | 167篇 |
2006年 | 130篇 |
2005年 | 140篇 |
2004年 | 100篇 |
2003年 | 70篇 |
2002年 | 55篇 |
2001年 | 17篇 |
2000年 | 15篇 |
1999年 | 10篇 |
1998年 | 8篇 |
1997年 | 2篇 |
1996年 | 2篇 |
1993年 | 1篇 |
1990年 | 1篇 |
1988年 | 1篇 |
1986年 | 1篇 |
1966年 | 2篇 |
Background
The objective of this study is to investigate the perceptions of first and third year medical students on self-study and reporting processes of Problem-based Learning (PBL) sessions and their usage of learning resources. 相似文献Background
Hereditary angioedema (HAE) attacks can be provoked with psychological factors. The aim of this study was to assess the effects of anxiety, depression and stress related to COVID-19 pandemic on disease activity of HAE patients during the quarantine period (QP) and the return to normal period (RTNP).Methods
This study was conducted between March 2020 and September 2020 in four allergy centres. Demographic, clinical features and mental health status were evaluated in QP (from March to the beginning of June) and RTNP (from June to the beginning of September) applied by the government. The 10-point visual analogue scale (VAS10) was used to define the severity of HAE attacks. Depression, Anxiety and Stress Scales-21 (DASS-21) and Fear of COVID-19 (FC-19) scale were performed to assess mental health status.Results
139 HAE patients were included in the study. In QP, median attack numbers and median VAS10 scores were 5 (min-max: 0–45) and 6 (min-max: 0–10), respectively. HAE attack numbers, DASS-21 stress, anxiety, depression and total DASS-21 scores, and FC-19 scores were higher in QP than RTNP (p = 0.001, p < 0.001, p = 0.001, p < 0.001, p < 0.001, p < 0.001, respectively). However, there was no difference in attack severity scores between the two periods (p > 0.05).Conclusions
This study revealed that the restriction measures during COVID-19 outbreak cause an increase in the number of HAE attacks in relation to anxiety, depression, stress and fear of COVID-19 pandemic. Therefore, it is important to provide psychological support to HAE patients during the pandemic.Cardiovascular disease is one of the major causes of mortality in anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV). Metabolic syndrome (MetS) is associated with increased cardiovascular risk in the normal population. However, MetS in AAV has not been adequately investigated. We aimed to determine MetS prevalence and associated factors in AAV patients.
MethodsThirty-seven AAV patients and 42 healthy controls were enrolled. MetS was determined by International Diabetes Federation (IDF) and National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATPIII) criteria. The relationship between clinical features of AAV and MetS was also investigated.
ResultsMetS was significantly higher in AAV patients than controls by NCEP-ATPIII (51.4% vs. 26.2%, p 0.022) and IDF (62.2% vs. 35.7%, p 0.020). When AAV patients with MetS were compared to those without, there were significant differences in age, CRP, GFR and NT-pro-BNP. Age [58 (13) vs. 50 (8) years p: 0.028], CRP [4.0 (3.6) vs. 3.2 (1.0) mg/l, p 0.021] and NT-pro-BNP [173.5 (343.7) vs. 106.0 (103.0) pg/ml, p 0.013] were significantly higher in AAV patients with MetS than those without; GFR was significantly lower [38 (46) vs. 83 (51) ml/min/1.73 m2, p 0.004]. ROC curve analysis showed NT-pro-BNP?>?58.0 ng/ml predicted MetS with 87.1% sensitivity and 46.7% specificity (Area under curve: 0.71, CI 0.536–0.902, p 0.041). Multivariate analysis revealed age [OR (95% CI): 1.180 (1.010–1.370), p 0.039] and NT-pro-BNP?>?58 pg/ml [OR (95% CI): 5.5 (1.02–30.1) p 0.047] were independent predictors of MetS in AAV patients.
ConclusionMetS is significantly higher in AAV patients than controls and is associated with age and NT-pro-BNP. Screening and treating MetS may improve prognosis in AAV patients.
相似文献Trajet intra-pancréatique de l'artère splénique associé à des anomalies pancréatiques
Résumé Sur le cadavre d'un homme de 47 ans, l'artère splénique présentait un trajet partiel à travers le pancréas. De plus, le pancréas paraissait volumineux et avait une forme inhabituelle, il n'était pas possible de différencier le col du pancréas, le processus uncinatus était absent, il y avait deux conduits pancréatiques. La raison probable de ces variations multiples se trouverait dans la fusion anormale des bourgeons pancréatiques dorsal et ventral en raison de leurs niveaux d'origine différents.相似文献
Anomalies musculaires et neurovasculaires de la région glutéale : un nerf pudendal atypique
Résumé Sur deux sujets — un homme et une femme — l'association d'anomalies musculaires et de variations neurovasculaires ont été observées dans la région glutéale. Sur chacun des cadavres, toutes ces particularités étaient situées du même côté. Chez le cadavre mâle, il y avait duplication du muscle piriforme et division haute associée du nerf sciatique. Chez le cadavre femelle, outre ces anomalies, les muscles jumeaux supérieur et inférieur, le muscle obturateur interne, ainsi que les vaisseaux et le nerf pudendal, passaient en arrière du ligament sacrotubéral. Si la duplication du muscle piriforme et la division haute du nerf sciatique ont déjà été rapportées, à notre connaissance les autres anomalies n'ont encore jamais été signalées. Les rapports atypiques des vaisseaux honteux internes et du nerf honteux avec le ligament sacro-tubéral comme dans notre cas, pourraient induire une congestion veineuse voire une obstruction artérielle et entraîner un dysfonctionnement du pénis et des algies périnéales. Ces anomalies de la région glutéale n'ont pas un simple intérêt académique mais peuvent être d'importance pratique pour la chirurgie de la région.相似文献