全文获取类型
收费全文 | 2178篇 |
免费 | 176篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 42篇 |
妇产科学 | 36篇 |
基础医学 | 478篇 |
口腔科学 | 24篇 |
临床医学 | 229篇 |
内科学 | 521篇 |
皮肤病学 | 97篇 |
神经病学 | 123篇 |
特种医学 | 64篇 |
外科学 | 335篇 |
综合类 | 6篇 |
一般理论 | 1篇 |
预防医学 | 80篇 |
眼科学 | 25篇 |
药学 | 137篇 |
中国医学 | 10篇 |
肿瘤学 | 142篇 |
出版年
2023年 | 18篇 |
2022年 | 108篇 |
2021年 | 134篇 |
2020年 | 59篇 |
2019年 | 74篇 |
2018年 | 97篇 |
2017年 | 65篇 |
2016年 | 94篇 |
2015年 | 74篇 |
2014年 | 103篇 |
2013年 | 98篇 |
2012年 | 133篇 |
2011年 | 158篇 |
2010年 | 83篇 |
2009年 | 77篇 |
2008年 | 128篇 |
2007年 | 139篇 |
2006年 | 116篇 |
2005年 | 118篇 |
2004年 | 81篇 |
2003年 | 67篇 |
2002年 | 62篇 |
2001年 | 25篇 |
2000年 | 13篇 |
1999年 | 17篇 |
1998年 | 15篇 |
1997年 | 16篇 |
1996年 | 5篇 |
1995年 | 12篇 |
1994年 | 8篇 |
1993年 | 7篇 |
1992年 | 9篇 |
1991年 | 20篇 |
1990年 | 11篇 |
1989年 | 15篇 |
1988年 | 9篇 |
1987年 | 8篇 |
1986年 | 15篇 |
1985年 | 9篇 |
1983年 | 5篇 |
1982年 | 5篇 |
1980年 | 3篇 |
1978年 | 4篇 |
1977年 | 6篇 |
1976年 | 4篇 |
1975年 | 4篇 |
1972年 | 5篇 |
1971年 | 3篇 |
1970年 | 3篇 |
1966年 | 4篇 |
排序方式: 共有2364条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
N. Z. Klyueva D. B. Ryzhov S. V. Kulikov S. K. Churina 《Bulletin of experimental biology and medicine》1997,124(2):751-753
Injection of a synthetic analog of parathyroid hypertensive factor to WKY rats considerably increases and prolongs pressor
response to adrenaline. Synthetic analog injected after adrenaline induces a short-term (3–4 min) and potent (to 250%) rise
of arterial pressure. Each subsequent injection of the synthetic analog induces a less pronounced in the amplitude and duration
pressor response. The α-adrenoblocker phentolamine completely abolishes the effects of the parathyroid hypertensive factor
analog.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 124, No. 8, pp. 148–150, August, 1997 相似文献
6.
7.
Ischemic postconditioning: brief ischemia during reperfusion converts persistent ventricular fibrillation into regular rhythm 总被引:31,自引:0,他引:31
Michael Galagudza Dmitry Kurapeev Sarkis Minasian Guro Valen Jarle Vaage 《European journal of cardio-thoracic surgery》2004,25(6):406-1010
Objectives: Brief episodes of myocardial ischemia-reperfusion employed during reperfusion after a prolonged ischemic insult may attenuate the total ischemia-reperfusion injury. This phenomenon has been termed ischemic postconditioning. In the present study, we studied the possible effect of postconditioning on persistent reperfusion-induced ventricular fibrillation (VF) in the isolated rat heart model. Methods: Isolated Langendorff-perfused rat hearts (n=46) were subjected to 30 min of regional ischemia and reperfusion. The hearts with persistent VF (n=11) present after 15 min of reperfusion were then randomly assigned into one of the two groups: (1) control hearts (n=6), in which perfusion was continued without intervention; (2) postconditioned hearts (n=5) subjected to 2 min of global ischemia followed by reperfusion. Left ventricular pressures, heart rate, coronary flow, and electrogram were monitored throughout the experiment. Results: Conversion of VF into regular rhythm was observed in all hearts subjected to postconditioning. Regular beating was maintained by all postconditioned hearts during the subsequent reperfusion. None of the hearts in the control group had normal rhythm at the end of the experiment. At the end of reperfusion, the left ventricular developed pressure was lower in beating postconditioned hearts compared to the hearts that did not develop persistent VF. Conclusions: Ischemic postconditioning possesses strong antiarrhythmic effect against persistent reperfusion-induced tachyarrhythmias. Postconditioning may be an interesting, novel adjunct strategy to protect the heart. 相似文献
8.
9.
Verbenko DA Pogoda TV Spitsyn VA Mikulich AI Bets LV Bebyakova NA Ivanov VP Abolmasov NN Pocheshkhova EA Balanovskaya EV Tarskaya LA Sorensen MV Limborska SA 《European journal of human genetics : EJHG》2003,11(6):444-451
Apolipoprotein B 3' (3' ApoB) minisatellite polymorphism was studied in healthy unrelated individuals from the Russian Federation and the Republic of Belarus, in 10 populations from five ethnic groups: Russians, Byelorussians, Adygeis, Kalmyks and Yakuts. The analysis was carried out using PCR and electrophoresis followed by silver staining. Overall, 25 alleles of the 3' ApoB minisatellite, ranging from 25 to 55 repeats, were detected. Heterozygosity indices were high and varied from 0.73 to 0.84. The distributions of alleles of this minisatellite in the Caucasoid populations (Russians, Byelorussians and Adygeis) had a bimodal character, whereas that for Mongoloid populations (Kalmyks and Yakuts) had a unimodal distribution. Nei's genetic distances between the populations studied and some reference populations of Europe and Asia were estimated. Despite their allele distribution homogeneity, different East Slavonic ethnic groups were clearly resolved by multidimensional analyses. The East Slavonic and Adygei populations revealed a high similarity with European Caucasoids. The Mongoloid populations (Kalmyks and Yakuts) were considerably different from those of the European Caucasoid populations, but were similar to other Asian Mongoloid populations. The results demonstrate the variability of 3' ApoB minisatellite polymorphism not only in distant populations but also, to a certain extent, in genetically relative ones. 相似文献
10.
Laura McGillis Nimish Mittal Daniel Santa Mina Joyce So Medha Soowamber Aliza Weinrib Leslie Soever Dmitry Rozenberg Louis Liu Yvonne Tse Joel Katz George S Charames Kieran Murphy Peter Vadas Maxwell P Slepian Scott Walsh Lindsay Wilson Arnon Adler Alyssa Franzese Laura Hussey Dayna‐Lynn Nevay Juan Guzman Hance Clarke 《American journal of medical genetics. Part A》2020,182(3):484-492
The new 2017 diagnostic criteria for hypermobile Ehlers–Danlos Syndrome (hEDS) provide a framework for diagnosing hEDS but are more stringent than the previous Villefranche criteria. Our clinical experience at the GoodHope EDS clinic was that the 2017 criteria left many highly symptomatic patients without a diagnosis of hEDS. We conducted a retrospective cohort study to confirm our clinic experience and assess the accuracy of the 2017 diagnostic criteria for hEDS in patients who had a previous hEDS diagnosis based on the Villefranche criteria. Our study found that 15% (n = 20 of 131) of patients with a prior diagnosis of hEDS met the 2017 diagnostic criteria, and many of the traits used to distinguish hEDS were not significantly more frequent in patients who met 2017 criteria versus those who did not. In both groups objective systemic manifestations were found less frequently than subjective systemic manifestations. Beighton score (BS) as assessed by primary care practitioner was found to be higher than assessment by EDS practitioner in 81% (n = 74 of 91) of cases. Generalized joint hypermobility was confirmed in only 46% (n = 51 of 111) of patients who had a previous diagnosis of hEDS. Higher BS did not correlate with increased number of systemic manifestations in our cohort. Common comorbidities of hEDS were found with similar frequency in those who met 2017 criteria and those who did not. Based on our cohort, the 2017 hEDS diagnostic criteria require refinement to improve its diagnostic accuracy. 相似文献