全文获取类型
收费全文 | 1221篇 |
免费 | 87篇 |
国内免费 | 8篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 19篇 |
妇产科学 | 12篇 |
基础医学 | 149篇 |
口腔科学 | 12篇 |
临床医学 | 104篇 |
内科学 | 285篇 |
皮肤病学 | 7篇 |
神经病学 | 66篇 |
特种医学 | 87篇 |
外科学 | 183篇 |
综合类 | 48篇 |
预防医学 | 100篇 |
眼科学 | 22篇 |
药学 | 64篇 |
中国医学 | 1篇 |
肿瘤学 | 155篇 |
出版年
2023年 | 12篇 |
2022年 | 9篇 |
2021年 | 32篇 |
2020年 | 28篇 |
2019年 | 36篇 |
2018年 | 33篇 |
2017年 | 23篇 |
2016年 | 20篇 |
2015年 | 23篇 |
2014年 | 26篇 |
2013年 | 50篇 |
2012年 | 53篇 |
2011年 | 73篇 |
2010年 | 41篇 |
2009年 | 33篇 |
2008年 | 44篇 |
2007年 | 54篇 |
2006年 | 50篇 |
2005年 | 58篇 |
2004年 | 54篇 |
2003年 | 59篇 |
2002年 | 44篇 |
2001年 | 51篇 |
2000年 | 34篇 |
1999年 | 34篇 |
1998年 | 9篇 |
1997年 | 14篇 |
1996年 | 15篇 |
1995年 | 12篇 |
1994年 | 11篇 |
1993年 | 13篇 |
1992年 | 29篇 |
1991年 | 25篇 |
1990年 | 26篇 |
1989年 | 7篇 |
1988年 | 22篇 |
1987年 | 17篇 |
1986年 | 20篇 |
1985年 | 17篇 |
1984年 | 11篇 |
1983年 | 13篇 |
1982年 | 10篇 |
1980年 | 5篇 |
1970年 | 3篇 |
1969年 | 3篇 |
1968年 | 5篇 |
1967年 | 3篇 |
1956年 | 4篇 |
1942年 | 3篇 |
1935年 | 3篇 |
排序方式: 共有1316条查询结果,搜索用时 15 毫秒
1.
2.
This paper provides a comprehensive methodological review of the literature assessing the relationship between marital satisfaction and communication. The investigations vary greatly in the adequacy of their assessment measures and soundness of their research design. Although it is generally concluded that both content and process communication are related to marital satisfaction, replication of the better designs is necessary. Specific findings and their practical implications for both future research and marital therapy are discussed. 相似文献
3.
Edward J Boland Mary MacDougall David L Carnes Sabine H Dickens 《Dental materials》2006,22(4):338-345
Recently, a resin-based calcium phosphate cement (RCPC) has been reported as a remineralizing pulp-capping or lining cement. RCPC consists mainly of tetracalcium and dicalcium phosphates, ethoxylated bisphenol A dimethacrylate and pyromellitic glycerol dimethacrylate monomers and photo- and chemical initiators. OBJECTIVES: Here, the cytotoxic effects of RCPC were evaluated. The hypothesis was that RCPC induced only minor cytotoxic response in immortalized murine odontoblast and pulp cells, comparable to that produced by similar dimethacrylates due to unpolymerized dimethacrylate monomer present after curing. METHODS: Cytotoxicity was determined following the changes in cell succinate dehydrogenase activity after 24 h exposure to the cement components and after a 24 h recovery period. A fourfold range of concentrations was tested of the monomers, the eluate of cured RCPC leached in Dulbecco's modified Eagle's medium, and crushed cured cement in dimethyl sulfoxide. RESULTS: The monomers themselves had cytotoxicities similar to those reported for other dimethacrylates, although they are significantly less toxic than Bis-GMA. Differential cell sensitivity was demonstrated, with the pulp cells having greater sensitivity to the unpolymerized monomer than the odontoblast-like cells. The leached components have cytotoxicity similar to that of the free monomers. The crushed material demonstrated no apparent cytotoxicity at the dilutions tested. SIGNIFICANCE: These data demonstrate that RCPC has an in vitro cytotoxicity that is comparable to other materials containing dimethacrylate monomers and suggest that the material may be suitable for use in dental restorations. The data also indicate that the pulp cells appear more sensitive to dimethacrylates than the odontoblasts. 相似文献
4.
5.
Carol E. Golin Katherine Tiller E. Byrd Quinlivan Catherine A. Grodensky Maureen Boland 《AIDS and behavior》2007,11(1):72-83
The epidemiology of HIV infection in the US in general, and in the southeast, in particular, has shifted dramatically over the past two decades, increasingly affecting women and minorities. The site for our intervention was an infectious diseases clinic based at a university hospital serving over 1,300 HIV-infected patients in North Carolina. Our patient population is diverse and reflects the trends seen more broadly in the epidemic in the southeast and in North Carolina. Practicing safer sex is a complex behavior with multiple determinants that vary by individual and social context. A comprehensive intervention that is client-centered and can be tailored to each individual’s circumstances is more likely to be effective at reducing risky behaviors among clients such as ours than are more confrontational or standardized prevention messages. One potential approach to improving safer sex practices among people living with HIV/AIDS (PLWHA) is Motivational Interviewing (MI), a non-judgmental, client-centered but directive counseling style. Below, we describe: (1) the development of the Start Talking About Risks (STAR) MI-based safer sex counseling program for PLWHA at our clinic site; (2) the intervention itself; and (3) lessons learned from implementing the intervention. 相似文献
6.
The fate of gallstones spilled during laparoscopic cholecystostomy has been thought to be relatively benign. Recent experience and a review of the recent literature shows that this is not always the case. We report three cases of complications of retained stones and analyse the literature with regard to types of complications, time to presentation, and recommendations for managing spilled gallstones. Retained gallstones have been shown to cause adhesions in the rat and inflammatory reactions in dogs with no evidence of absorption. The average time to presentation of complications arising from retained gallstones is 27.3 weeks. Complications include: Intraabdominal abscess formation with or without abdominal wall sinus tract formation, persisting abdominal wall sinus tracts from port site abscess, subhepatic inflammatory masses, cholelithoptysis, microabscesses and granuloma formation, liver abscess and “dumbell” shaped abscess with one side of the “dumbell” forming a subcutaneous abscess. We recommend the judicious use of retrieval devices during the extraction phase of the laparoscopic cholecystectomy, diligent removal of any spilled stones and awareness of delayed postoperative pain and tenderness as a harbinger of symptomatic retained gallstones. Documentation of intraoperative gallstone spillage, volume, type of gallstones, and effort to retrieve is recommended. 相似文献
7.
8.
9.
Microplate technique to determine hemolytic activity for routine typing of Listeria strains. 总被引:15,自引:2,他引:15 下载免费PDF全文
L Dominguez Rodriguez J A Vazquez Boland J F Fernandez Garayzabal P Echalecu Tranchant E Gomez-Lucia E F Rodriguez Ferri G Suarez Fernandez 《Journal of clinical microbiology》1986,24(1):99-103
Because the hemolysis produced by Listeria monocytogenes and Listeria seeligeri on blood agar is frequently difficult to interpret, we developed a microplate technique for the routine determination of hemolytic activity with erythrocyte suspensions. This microtechnique is a simple and reliable test for distinguishing clearly between hemolytic and nonhemolytic strains and could be used instead of the CAMP (Christie-Atkins-Munch-Petersen) test with Staphylococcus aureus in the routine typing of Listeria strains. Furthermore, our results suggest that the quantitation of the hemolytic activity of the Listeria strains, along with the D-xylose, L-rhamnose, and alpha-methyl-D-mannoside acidification tests, allows the differentiation of L. monocytogenes, L. seeligeri, and Listeria ivanovii. We also observed that the treatment of erythrocytes with crude exosubstances of rhodococcus equi, Pseudomonas fluorescens, Acinetobacter calcoaceticus, and S. aureus enhanced the hemolytic activity of all Listeria strains with this characteristic. 相似文献
10.
The purpose of this study was to engage women with HIV disease in a qualitative needs assessment for psychological services. Focus groups/interviews were held to develop an understanding of these women's experiences and perceptions of services needed within a support group format. Results support women's interest in and perceived need for psychosocial group intervention and provide feedback on how to structure groups, including considerations for the facilitator, concrete barriers to address, and attention to group attributes and guidelines. These results support ongoing development of psychosocial support groups for women with HIV disease and further exploration of the efficacy of group models for the diverse subgroups of women with HIV/AIDS. 相似文献