一株具有抗稻瘟霉活性的海洋细菌32-11-2-2的筛选和分离鉴定

目的:从中国东海微生物样品中分离筛选活性细菌菌株,并对活性菌株32-11-2-2进行鉴定.方法:采用无限稀释和平板划线法分离微生物样品,利用稻瘟霉模型进行活性筛选;并对其中的活性菌株32-11-2-2的形态、培养特征以及生理生化特征进行研究,使用16S rDNA序列分析的方法对菌株32-11-2-2进行了分类鉴定.结果:分离得到421株细菌,包括活性菌株54株,其中活性菌株32-11-2-2是一株弱嗜盐菌,具有陆地芽孢杆菌的形态特点,能产生胞外淀粉酶、过氧化氢酶,液化明胶、石蕊牛奶反应阳性,16S rDNA序列分析该菌株与枯草芽孢杆菌(Bacillus subtilis)同源性达到98%以上.结论:活性菌株32-11-2-2是一株适应了海洋环境的枯草芽孢杆菌.     

复方盐酸萘甲唑啉鼻用喷剂治疗慢性单纯性鼻炎的临床观察

目的 观察复方盐酸萘甲唑啉鼻用喷剂治疗慢性单纯性鼻炎的疗效及不良反应.方法 500例慢性单纯性鼻炎患者连续使用复方盐酸萘甲唑啉鼻用喷剂4周,200例对照组患者使用生理盐水喷鼻,使用视觉模拟量表(visual analoguescale,VAS)症状量化评估治疗效果,比较2组患者的疗效.结果 使用复方盐酸萘甲唑啉鼻用喷剂...     

喉部低度恶性炎性肌纤维母细胞瘤1例

炎性肌纤维母细胞瘤(inflammatory myofibroblastic tumor,IMT)是一种少见的好发于肺组织的间叶性交界性肿瘤,由分化的肌纤维母细胞性梭形细胞和淋巴细胞、浆细胞等炎症细胞组成,本文回顾分析我科1例位于喉部的低度恶性IMT,以提高对本病的认识。     

少见鼻中隔脓肿二例

鼻中隔脓肿多见于鼻外伤或鼻中隔手术,2006-2007年我科诊治2例病因不典型的少见鼻中隔脓肿患者,现报告如下.     

声带息肉伴真菌感染1例

患者,男,43岁,因反复声音嘶哑7年余于2009年6月22日来我院就诊。患者近7年来无明显诱因反复出现声音嘶哑,未给予重视,本次发病为劳累后声嘶加重,无咽痛、咳嗽、咳痰、鼻塞等上呼吸道感染症状。既往体健,否认有肿瘤、结核、糖尿病、肝肾功能不全等慢性疾病史。电子喉镜检查     

鼻内镜下曲安奈德冲洗咽鼓管治疗慢性分泌性中耳炎

目的探讨鼻内镜下曲安奈德冲洗咽鼓管治疗慢性分泌性中耳炎的疗效。方法 42例慢性分泌性中耳炎患者分为2组,治疗组22例29耳,鼻内镜下用曲安奈德冲洗咽鼓管;对照组20例24耳,鼓室内注射地塞米松、α-糜蛋白酶,比较两组疗效。结果治疗组治愈22耳,占75.86%(22/29),好转3耳,占10.34(3/29)%,总有效率86.20%;对照组治愈17耳,占70.83(17/24)%,好转3耳,占12.50%(3/24),总有效率83.33%,两组总有效率无明显差异(P>0.05),但治疗组首次治疗有效率79.31%(23/29)高于对照组首次治疗有效率58.33%(14/24)。结论鼻内镜下曲安奈德冲洗咽鼓管治疗慢性分泌性中耳炎疗效与传统鼓膜穿刺给药法疗效相近,但首次治疗有效率高,为慢性分泌性中耳炎的治疗提供了一种新选择。     

远海长航舰艇人员阻塞性睡眠呼吸暂停低通气综合征问卷调查

目的 对远海长航舰艇人员阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apneahypopnea syndrome,OSAHS)情况进行问卷调查,为进一步进行相关研究提供参考.方法 在"和谐使命-2010"卫勤演练期间,对参与亚丁湾护航的2艘舰艇部分官兵进行OSAHS问卷调查.其中A组某舰官兵114名.出航时间3个月;B组为某舰官兵139名.出航时间6个月.对A、B组出航前后睡眠情况进行统计,并对2组的睡眠时间和OSAHS情况进行比较.结果 B组每日的睡眠时间较A组缩短.A组有OSAHS倾向的19人,发生率16.7%;B组有34人,发生率24.5%,B组高于A组.2组中共有155人(61.3%)认为出航后睡眠情况较出航前差.结论 远海长航舰艇人员OSAHS倾向的发生率较高,随着出航时间的延长睡眠情况逐渐变差,OSAHS倾向的发生率增高.提示远海长航舰艇人员OSAHS情况值得进一步研究.

Abstract：

Objective To perform a questionnaire on the obstructive sleep apnea-hypopnea syndrome (OSAHS) among the prolonged ocean-going shipboard personnel, so as to provide reference data for further study of this kind. Methods During the medical support exercise of " Operation Harmony-2010", a questionnaire on OSAS was performed in the officers and men of the 2 naval vessels involved in the escort mission in the Gulf of Aden. Participating in the questionnaire were officers and men of a certain naval vessels belonging to group A in a prolonged deployment at sea for a duration of 3 months. The other 139 officers and men of the other naval vessels belonging to group B were deployed there for a duration of 6 months. Statistical analyses were made on the changes in the sleep status of the 2 groups both before and after deployment. Then, the sleep time and OSAHS were compared and analyzed between the 2 groups. Results Sleeping time each day for group B was shorter than that for group A. The number of people in group A who had a tendency of developing OSAHS was 19, with the incidence rate being 16. 1% , while 34 people in group B developed OSAHS, with the incidence rate being 24.5%. The incidence rate of group B was obviously higher than that of group A. There were altogether 155 people (61. 3%) in the 2 groups, who thought their sleeping status after deployment became worse, when it was compared with that before deployment. Conclusions Prolonged oceangoing shipboard personnel had a higher incidence rate of OSAHS. With the prolonging of deployment, sleeping among the deployed personnel would become worse and the tendency of developing OSAHS would become higher. This indicated that OSAHS occurring among the prolonged ocean-going shipboard personnel was a medical problem worth further close study.     

鼻中隔偏曲矫正术治疗变态反应性鼻炎106例疗效观察

变态反应性鼻炎(allergic rhinitis,AR)是耳鼻咽喉头颈外科的常见病之一,且随着工业的发展和生活环境的改变,变态反应性鼻炎的发病率近年来有增高的趋势,已成为亟待解决的全球性健康问题,严重影响了患者的生活质量,其发病机制至今尚不明确。目前变应性鼻炎常规以药物保守治疗为主,但不良反应大、易反复,尤其是一部分伴有鼻中隔偏     

远海长航舰艇人员阻塞性睡眠呼吸暂停低通气综合征问卷调查

目的 对远海长航舰艇人员阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apneahypopnea syndrome,OSAHS)情况进行问卷调查,为进一步进行相关研究提供参考.方法 在"和谐使命-2010"卫勤演练期间,对参与亚丁湾护航的2艘舰艇部分官兵进行OSAHS问卷调查.其中A组某舰官兵114名.出航时间3个月;B组为某舰官兵139名.出航时间6个月.对A、B组出航前后睡眠情况进行统计,并对2组的睡眠时间和OSAHS情况进行比较.结果 B组每日的睡眠时间较A组缩短.A组有OSAHS倾向的19人,发生率16.7%;B组有34人,发生率24.5%,B组高于A组.2组中共有155人(61.3%)认为出航后睡眠情况较出航前差.结论 远海长航舰艇人员OSAHS倾向的发生率较高,随着出航时间的延长睡眠情况逐渐变差,OSAHS倾向的发生率增高.提示远海长航舰艇人员OSAHS情况值得进一步研究.     

利多卡因局部麻醉致惊厥一例

扁桃体低温等离子射频消融术后反应轻、出血少、痛苦少、操作简单等优点，在临床上的应用日益广泛，在绝大多数情况下这一技术是安全的，其致死性的并发症主要包括麻醉药中毒及术后大出血等，其中利多卡因所致的心血管及中枢神经系统毒性反应值得重视。现报道扁桃体消融术前局部浸润麻醉注射利多卡因诱发惊厥1例。