排序方式: 共有36条查询结果,搜索用时 78 毫秒
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目的探讨18F-FDG PET-CT-MRI多模态成像对胰腺癌的诊断、分期及预后预测价值。方法回顾性分析2018年3月至2022年9月因怀疑胰腺占位性病变于武汉大学人民医院行18F-FDG PET-CT-MRI多模态成像的87例患者的临床及影像学资料。以组织病理学结果为诊断"金标准", 分析并Kappa检验18F-FDG PET-CT-MRI多模态成像与传统18F-FDG PET-CT对胰腺癌的诊断与分期诊断效能。Kaplan-Meier总生存(OS)分析, Cox模型预后因素分析。评估18F-FDG PET-CT-MRI多模态成像技术各成像生物标志物与OS的关系。结果 18F-FDG PET-CT-MRI诊断胰腺癌的敏感性、特异性与准确性分别为98.65%、76.92%与95.40%, 高于18F-FDG PET-CT, 与病理结果具有较高的一致性(K=0.807)。在TNM分期方面, 18F-FDG PET-CT-MRI显像诊断胰腺癌TNM分期的准确性分别为97.30%、97.30%、100%, 与病理分期一致性检验结果分别为0.960、0.976、1.000, 均优于18F-FD... 相似文献
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<正>患者男,42岁,18个月前因“双下肢酸胀乏力”于外院确诊“自身免疫性郎飞结病”并接受利妥昔单抗、醋酸泼尼松及免疫球蛋白治疗,近1个月症状加重;既往体健。查体:双下肢肌肉稍萎缩,肌力3级,左膝及以下、右侧大腿及以下感觉减退,双侧直腿抬高试验阳性。实验室检查:脑脊液蛋白7 893.5 mg/L,Ig G5.21mg/L, 相似文献
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目的 探讨18F-FDG PET/CT与MRI异机融合在高级别脑胶质瘤(HGG)诊断中的价值。方法 回顾性分析90例经组织病理学证实的高级别脑胶质瘤(HGG)(n=31)、原发性中枢神经系统淋巴瘤(PCNSL)(n=20)和脑转移瘤(BM)(n=39)患者。所有患者同一天先后接受18F-FDG PET/CT和MRI双倍剂量增强扫描。采用视觉分析3组患者的病灶分布和形态特征,以及半定量参数最大标准化摄取值(SUVmax)、标准化摄取值均值(SUVmean)、肿瘤与对侧相应部位正常脑组织SUVmax的比值(T/N),采用Mann-Whitney U检验和多因素回归分析及受试者工作特征(ROC)曲线分析两两组间关系。评价异机融合18F-FDG PETCT/MRI在HGG鉴别诊断中的价值。结果 增强特征、占位效应和病灶部位在HGG、PCNSL和BM组间差异具有统计学意义(P<0.05);半定量分析中,PCNSL的SUVmax、SUV 相似文献
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原发性肝细胞癌和肝血管瘤是肝内最常见的良、恶性肿瘤,对于二者的鉴别诊断一直是影像学诊断面临的重要问题。US、CF、MRI及其它影像学检查手段都涉及到对二者的诊断和鉴别诊断,对于3cm以上的病灶,所有影像学检查手段的检出率和定性准确率几乎没有太大的差别,但对于3cm以下的病变,检出敏感性和定性准确性均以增强MRI最高。本文将对MRI增强扫描中HCC和肝血管瘤的影像特征进行详细阐述,以进一步提高MRI对二者的诊断水平。 相似文献
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Objective The purpose of the present study is to compare the pharmacokinetic and biodistribution properties of 99Tcm N-mercaptopyridine-N-oxide (99 Tcm N-MPO) with 99 Tcm-sestamibi (99 Tcm-MIBI) in normal dogs, and to investigate the potential of 99TcmN-MPO as a myocardial perfusion agent in canines with acute myocardial infarction. Methods Twelve healthy mongrel dogs were injected intravenously with 99TcmN-MPO (n = 6) or 99Tcm-MIBI (n = 6). Tracer kinetics in body fluids were determined by collecting blood of 1 ml via a femoral vein catheter at 30 s, 1,2,3,4,5, 10, 20, 30, 40, 60and 90 min post-injection (p. i.). The collected blood samples were weighed and counted for radioactivity in a γ-counter. Anterior and posterior planar γ-camera images were collected at 10, 20, 30, 60, 90, and 120 min after injection, with organ uptake quantified by region-of-interest (ROIs) analysis. For comparison, 99Tcm-MIBI was also evaluated in the same twelve dogs. Canine infarct models were set up by micro-invasive interventional embolization. SPECT images in the canine infarct model were collected 24 hours after myocardial infarction at 30 min and 60 min after the administration of 99Tcm N-MPO (n = 5) or 99Tcm-MIBI (n = 5). Results Both of 99Tcm N-MPO and 99Tcm-M1BI had a rapid blood clearance with less than 50% of initial radioactivity remaining at 1 min [99TcmN-MPO: (35. 77 ± 6. 31)% ID/mg ,99Tcm-MIBI (34. 46 ± 6. 83) % ID/mg] and less than 5% at 30 min p. i. [99Tcm N-MPO(3. 11 ± 1.44) % ID/mg,99Tcm-MIBI (2.93 ±0. 39)% ID/mg] . After injection, 99TcmN-MPO showed significant accumulation in the myocardium and prolonged retention. This rapid liver clearance of 99TcmN-MPO led to favorable heart-to-liver ratios, reaching values of 0. 54 ±0. 06 at 10 min, 1.02 ±0. 06 at 30 min, and 1.38 ±0. 06 at 60 min p. i.In contrast, the heart/liver ratio of 99Tcm-MIBI remained low at all time points (0. 46 ± 0. 03 at 10 min,0. 63 ±0. 03 at 30 min, and 0. 62 ± 0. 12 at 60 min p. i.). SPECT imaging studies in canines with acute myocardial infarction indicated that good visualization of the left ventricular wall and perfusion defects could be achieved at 30 min after administration of 99TcmN-MPO, but not 99Tcm-MIBI. Conclusion The combination of high heart uptake and rapid liver clearance makes 99TcmN-MPO a promising new radiotracer for myocardial perfusion imaging. 相似文献
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继首届中国分子影像学高级研讨会于2004年在哈尔滨成功举办后,由人民卫生出版社和哈尔滨医科大学联合主办,哈尔滨医科大学附属第四医院承办的第二届中国分子影像学高级研讨会于2008年1月18日在哈尔滨市召开,来自美国和中国的30名分子影像学专家和相关学科专家应邀参加了本次会议. 相似文献
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磁共振DWI在诊断急性脑梗塞中的初步应用 总被引:3,自引:0,他引:3
目的初步探讨弥散加权像(OWI)技术在诊断急性脑梗塞中的应用价值。方法收集22例急性脑梗塞患者中超急性期(小于6h)3例,急性期(6~24h)19例,均行常规T1WI、T2WI及DWI扫描,并比较病变显示的对比度、边界以及范围,计算病灶的ADC值与rADC值。结果①DWI对于显示病灶的对比度、边界以及范围均优于常规T1WI和T2WI;②所有22病例病灶的ADC值与rADE值均下降。结论磁共振DWI技术对急性脑梗塞病变敏感度高,有很高的诊断价值。 相似文献