全文获取类型
收费全文 | 1354篇 |
免费 | 26篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 35篇 |
妇产科学 | 7篇 |
基础医学 | 57篇 |
口腔科学 | 8篇 |
临床医学 | 123篇 |
内科学 | 150篇 |
皮肤病学 | 95篇 |
神经病学 | 289篇 |
特种医学 | 1篇 |
外科学 | 384篇 |
综合类 | 5篇 |
预防医学 | 9篇 |
眼科学 | 16篇 |
药学 | 30篇 |
肿瘤学 | 170篇 |
出版年
2022年 | 9篇 |
2021年 | 7篇 |
2017年 | 5篇 |
2016年 | 9篇 |
2015年 | 17篇 |
2014年 | 25篇 |
2013年 | 15篇 |
2012年 | 11篇 |
2011年 | 25篇 |
2010年 | 167篇 |
2009年 | 283篇 |
2008年 | 139篇 |
2007年 | 24篇 |
2006年 | 38篇 |
2005年 | 17篇 |
2004年 | 31篇 |
2003年 | 29篇 |
2002年 | 13篇 |
2001年 | 13篇 |
2000年 | 4篇 |
1999年 | 11篇 |
1998年 | 42篇 |
1997年 | 93篇 |
1996年 | 28篇 |
1995年 | 56篇 |
1994年 | 25篇 |
1993年 | 16篇 |
1992年 | 10篇 |
1991年 | 8篇 |
1990年 | 3篇 |
1989年 | 3篇 |
1987年 | 15篇 |
1986年 | 7篇 |
1983年 | 6篇 |
1982年 | 5篇 |
1981年 | 6篇 |
1980年 | 5篇 |
1979年 | 3篇 |
1978年 | 6篇 |
1975年 | 3篇 |
1967年 | 9篇 |
1966年 | 10篇 |
1965年 | 6篇 |
1961年 | 8篇 |
1959年 | 5篇 |
1958年 | 14篇 |
1957年 | 17篇 |
1956年 | 24篇 |
1955年 | 17篇 |
1954年 | 15篇 |
排序方式: 共有1381条查询结果,搜索用时 15 毫秒
1.
RYOSAKU TOMIYAMA FUKUNORI KINJO AKIRA HOKAMA TSUYOSHI MIYAGI HIROKI NAKASONE NAGISA KINJO HIROSHI SAKUGAWA ATSUSHI SAITO 《Digestive endoscopy》2003,15(2):125-127
We report a case of a patient in whom endoscopic band ligation was achieved for postpolypectomy gastric bleeding. A 76‐year‐old man visited our hospital because of anemia. Endoscopy revealed a gastric polyp, approximately 12 mm in diameter, on the lesser curvature in the distal gastric body. The polyp was considered to be the source of chronic anemia and was therefore removed by using standard careful snare‐cautery polypectomy technique. Four days later, follow‐up endoscopy was performed to evaluate the postpolypectomy site, and an active bleeding postpolypectomy ulcer was identified. Initial attempts to achieve hemostasis with ethanol injection were unsuccessful. Immediate hemostasis was obtained with a subsequent endoscopic band ligation device. There has been no recurrent bleeding. Endoscopic band ligation might be a good treatment modality for the treatment of a postpolypectomy gastric bleeding lesion. 相似文献
2.
3.
SHUICHI SHIMADA HARUO NAKAGAWA ICHIRO SHINTAKU SEIICHI SAITO YOICHI ARAI 《International journal of urology》2006,13(8):1121-1122
A 73-year-old male with a history of diabetes mellitus was admitted to our hospital for acute renal failure. An ultrasonogram revealed bilateral hydronephrosis, which worsened despite insertion of a bladder catheter. Nephrostomy catheters were positioned bilaterally, and Candida albicans was found in the urine culture. The patient was successfully treated with intermittent direct irrigation and i.v. antifungal agent therapy. Since 1977, approximately 50 cases of fungus balls or fungal bezoars in the urinary tract have been reported, but the majority of these cases have been characterized by unilateral ureteral or bladder involvement. Herein, we report a case of acute renal failure as a result of bilateral ureteral obstruction by Candida albicans fungus balls. 相似文献
4.
Samir Kumar Praharaj mbbs md dpm Nishant Goyal mbbs md dpm Sukanto Sarkar mbbs md dpm Dhruv Bagati mbbs Prakriti Sinha mp hil Vinod Kumar Sinha mbbs md dpm 《Psychiatry and clinical neurosciences》2009,63(2):230-234
Reported herein is a case of obsessive–compulsive disorder with persistent and distressing musical obsessions along with other symptoms. Advanced source analysis of electroencephalographic data indicated high spectral power over the bifrontal region. The musical symptoms were resistant to pharmacotherapy but there was some reduction in frequency and duration of musical obsessions with thought-stopping technique. 相似文献
5.
6.
7.
8.
Abstract: We analyzed the expression of CEA, CA19-9, CA125, CA15-3 (DF3), PCNA and p53 immunohistochemically in 14 tissue specimens of mucosal cancers in adenoma, seven tubulovillous adenoma specimens, and 16 tubular adenoma specimens. The rates of positive staining for mucosal cancer in adenoma, tubulovillous adenoma and tubular adenoma specimens, respectively, were: for CEA: 100%, 85.7% and 75%; for CA19-9: 71.4%, 71.4% and 56.2%; for CA125:0%, 0% and 0%;for CA15-3 (DF3): 64.3 %, 0% and 0 %; for PCNA: 100%, 88.9% and 56.2%; and for p53: 35.7%, 0% and 0% . The results suggest that the expressions of CEA, CA19-9, CA15-3 (DF3), PCNA and p53 are related to colorectal tumorigenesis. None of the specimens studied showed staining for CA125, suggesting that CA125 is not involved in the early stages of colorectal carcinogenesis. There was no significant difference in the rates of positive staining for CEA and CA19-9 among mucosal cancer in adenoma, tubular adenoma and tubulovillous adenoma specimens. However, the rates of positive staining for PCNA and p53 were significantly higher in mucosal cancer in adenoma specimens than for tubular adenoma specimens (p<0.05), and the rate of CA15-3 (DF3) positive staining was significantly higher for mucosal cancer in adenoma than for tubulovillous adenoma (p<0.01) and tubular adenoma (p< 0.001) specimens. Therefore, the CA15-3 (DF3) antigen is an immunohistochemical marker for colorectal carcinomas. The present results suggest that CA15-3 (DF3), PCNA and p53 play important roles in the genesis of colorectal adenomas. 相似文献
9.
KAZUMI NOGUCHI JUN-ICHI TERANISHI HIROJI UEMURA NAOYA FUJIKAWA KAZUO SAITO TETSUO MURAI 《International journal of urology》2006,13(9):1259-1261
Antiandrogen withdrawal syndrome (AWS) is a well-established phenomenon in prostate cancer. However, responses to AWS are usually of limited duration, and a complete response (CR) is extremely rare. We present two patients who exhibited a chemical CR for more than 2 years after the discontinuation of steroidal antiandrogen chlormadinone acetate use. Whether patients who respond to antiandrogen withdrawal include a group of patients with a better prognosis remains uncertain. However, considering that the usual survival period of patients with hormone-resistant prostate cancer is approximately 12 months, both of the patients reported here, who are present in excellent physical condition, exhibiting an improved quality of life, and attending their hospital as outpatients, obviously acquired a prolonged survival because of AWS. 相似文献
10.
TAKAKO EGUCHI TAKUJI GOTODA ICHIRO ODA HISANAO HAMANAKA NORIAKI HASUIKE DAIZO SAITO 《Digestive endoscopy》2003,15(2):113-116
Background: Endoscopic mucosal resection (EMR) is widely accepted as a minimally invasive treatment for early gastric cancer (EGC) in Japan. However, the criteria for EMR must be strictly adhered to otherwise patients will miss the chance for additional therapy. We assess the important factor in expanding the indication of EMR. Methods: We investigated 1101 EGCs that had been resected by EMR at the National Cancer Center Hospital (NCCH), Tokyo, Japan, according to the indication recommended by Japanese Gastric Cancer Association (JGCA) and the expanded indication proposed by NCCH. Curability and local recurrence of the EMRs were assessed related to the applied indication and the number of resected specimens. Results: The recurrence rate of non‐evaluable resection was higher than that of evaluable resection (P < 0.0001). Eighty‐three lesions among 772 lesions in the JGCA group were non‐evaluable. Thirty‐seven leisons among 329 lesions in the NCCH group were non‐evaluable. There was no difference in the rate of non‐evaluable resection between JGCA and NCCH groups (P = 0.8329). However, the rate of curative resection was lower in the NCCH group than in the JGCA group (P = 0.0009). In piecemeal resection, there was no difference in the rate of non‐evaluable resection between JGCA and NCCH groups (P = 0.0527). In one‐piece resection, the rate of non‐evaluable resection was lower in the NCCH group than the JGCA group (P = 0.0137). Conclusion: Based on our series of cases, we propose one‐piece resection as a gold standard for EMR because it enables accurate histological evaluation, even in the EMR, according to the expanded indication. 相似文献