全文获取类型
收费全文 | 50811篇 |
免费 | 3359篇 |
国内免费 | 577篇 |
专业分类
耳鼻咽喉 | 982篇 |
儿科学 | 803篇 |
妇产科学 | 745篇 |
基础医学 | 8073篇 |
口腔科学 | 1142篇 |
临床医学 | 4575篇 |
内科学 | 9970篇 |
皮肤病学 | 1771篇 |
神经病学 | 3908篇 |
特种医学 | 2897篇 |
外科学 | 6811篇 |
综合类 | 307篇 |
现状与发展 | 3篇 |
一般理论 | 26篇 |
预防医学 | 2336篇 |
眼科学 | 1040篇 |
药学 | 4461篇 |
中国医学 | 641篇 |
肿瘤学 | 4256篇 |
出版年
2023年 | 369篇 |
2022年 | 1145篇 |
2021年 | 1839篇 |
2020年 | 994篇 |
2019年 | 1394篇 |
2018年 | 1619篇 |
2017年 | 1309篇 |
2016年 | 1860篇 |
2015年 | 2499篇 |
2014年 | 2836篇 |
2013年 | 3239篇 |
2012年 | 4724篇 |
2011年 | 4434篇 |
2010年 | 2769篇 |
2009年 | 2236篇 |
2008年 | 3129篇 |
2007年 | 2790篇 |
2006年 | 2525篇 |
2005年 | 2298篇 |
2004年 | 1891篇 |
2003年 | 1685篇 |
2002年 | 1470篇 |
2001年 | 690篇 |
2000年 | 660篇 |
1999年 | 510篇 |
1998年 | 278篇 |
1997年 | 252篇 |
1996年 | 182篇 |
1995年 | 143篇 |
1994年 | 124篇 |
1993年 | 133篇 |
1992年 | 182篇 |
1991年 | 209篇 |
1990年 | 172篇 |
1989年 | 172篇 |
1988年 | 167篇 |
1987年 | 131篇 |
1986年 | 116篇 |
1985年 | 106篇 |
1984年 | 81篇 |
1983年 | 82篇 |
1982年 | 70篇 |
1979年 | 93篇 |
1978年 | 76篇 |
1977年 | 62篇 |
1975年 | 74篇 |
1974年 | 53篇 |
1973年 | 53篇 |
1972年 | 55篇 |
1971年 | 72篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
3.
K.-C. Sung D.-C. Seo S.-J. Lee M.-Y. Lee S.H. Wild C.D. Byrne 《Nutrition, metabolism, and cardiovascular diseases : NMCD》2019,29(5):489-495
Background and aims
It is not known whether non alcoholic fatty liver disease (NAFLD) is a risk factor for diabetes in non obese, non centrally-obese subjects. Our aim was to investigate relationships between fatty liver, insulin resistance and a biomarker score for liver fibrosis with incident diabetes at follow up, in subjects who were neither obese nor centrally-obese.Methods and results
As many as 70,303 subjects with a body mass index (BMI) < 25 kg/m2 and without diabetes were followed up for a maximum of 7.9 years. At baseline, fatty liver was identified by liver ultrasound, insulin resistance (IR) by homeostatic model assessment of insulin resistance (HOMA-IR) ≥2.0, and central obesity by waist circumference (waist circumference ≥90 cm (men) and ≥85 cm (women). The Fibrosis-4 (FIB-4 score) was used to estimate extent of liver fibrosis. Cox proportional hazards models adjusted for confounders were used to estimate hazard ratios (aHRs) for incident diabetes. As many as 852 incident cases of diabetes occurred during follow up (median [IQR] 3.71 [2.03] years). Mean ± SD BMI was 22.8 ± 1.8 and 21.7 ± 2.0 kg/m2 in subjects with and without diabetes at follow up. In subjects without central obesity and with fatty liver, aHRs (95% CI) for incident diabetes at follow up were 2.17 (1.56, 3.03) for men, and 2.86 (1.50,5.46) for women. Similar aHRs for incident diabetes occurred with fatty liver, IR and the highest quartile of FIB-4 combined, in men; and there was a non significant trend toward increased risk in women.Conclusions
In normal weight, non-centrally obese subjects NAFLD is an independent risk factor for incident diabetes. 相似文献4.
5.
H J Kim C H Kang Y T Kim S-W Sung J H Kim S M Lee C-G Yoo C-T Lee Y W Kim S K Han Y-S Shim J-J Yim 《The European respiratory journal》2006,28(3):576-580
Although surgical lung resection could improve prognosis in some patients with multidrug-resistant tuberculosis (MDR-TB), there are no reports on the optimal candidates for this surgery. The aim of the present study was to elucidate the prognostic factors for surgery in patients with MDR-TB. Patients who underwent lung resection for the treatment of MDR-TB between March 1993 and December 2004 were included in the present study. Treatment failure was defined as greater than or equal to two of the five cultures recorded in the final 12 months of treatment being positive, any one of the final three cultures being positive, or the patient having died during treatment. The variables that affected treatment outcomes were identified through univariate and multivariate logistic regression analysis. In total, 79 patients with MDR-TB were included in the present study. The treatment outcomes of 22 (27.8%) patients were classified as failure. A body mass index <18.5 kg x m(-2), primary resistance, resistance to ofloxacin and the presence of a cavitary lesion beyond the range of the surgical resection were associated with treatment failure. Low body mass index, primary resistance, resistance to ofloxacin and cavitary lesions beyond the range of resection are possible poor prognostic factors for surgical lung resection in multidrug-resistant tuberculosis patients. 相似文献
6.
Sung Woo Lee Sung Hyuk Choi Yunsik Hong Wanbae Kim 《European journal of emergency medicine》2006,13(2):117-118
Generally, a computed tomography scan is conducted for the diagnosis of stroke in the emergency department, because these scans are easier and faster in the detection of stroke. If there are no signs of hemorrhage on computed tomography scan, an ischemic stroke is diagnosed and treated accordingly. A magnetic resonance imaging scan may be taken in order to verify ischemic stroke. This process may lead to improper treatment and is time consuming. To address this situation, case studies are presented in which magnetic resonance imaging diffusion-weighted imaging and gradient recalled echo were performed to detect hemorrhagic and ischemic stroke and particularly, subarachnoid hemorrhage, which is undetectable with a computed tomography scan. 相似文献
7.
Eun Sang Park Jung Im Na Seon Ok Kim Chang Hun Huh Sang Woong Youn Kyoung Chan Park 《Skin research and technology》2006,12(4):298-302
Background/purpose: Vitiligo and nevus depigmentosus (ND) present similar hypopigmented macules with significantly different prognoses. Although the distinction between the two diseases is important, differential diagnosis relies on medical history and physical examination, which is far from decisive in some cases. The Mexameter® is an objective skin color-measuring device, and has been reported to provide a reproducible and sensitive means of quantifying small skin color differences. In this study, we investigated the usefulness of a Mexameter® for discriminating these diseases.
Methods: A selection of 202 hypopigmented skin lesions (182 from vitiligo and 20 from ND) were the objects of this study. Using a Mexameter, MIs were obtained from lesions and symmetrically located control skin. RMIs, ratios of the MIs of lesional skins to control skins, were calculated.
Results: The mean MIs and RMIs were significantly different for vitiligo and ND. The mean RMI of ND lesions was 74±13, which was significantly higher than that of vitiligo lesions (50±24). No ND lesion had an RMI of <50%.
Conclusion: This study shows that the Mexameter® , an objective pigment-measuring device, can be used to achieve a more accurate diagnosis of hypopigmentary disorders, and that the relative melanin index (RMI), which represents the relative pigment levels, might be a more effective parameter than the melanin index (MI) itself for comparing pigmentation differences. 相似文献
Methods: A selection of 202 hypopigmented skin lesions (182 from vitiligo and 20 from ND) were the objects of this study. Using a Mexameter, MIs were obtained from lesions and symmetrically located control skin. RMIs, ratios of the MIs of lesional skins to control skins, were calculated.
Results: The mean MIs and RMIs were significantly different for vitiligo and ND. The mean RMI of ND lesions was 74±13, which was significantly higher than that of vitiligo lesions (50±24). No ND lesion had an RMI of <50%.
Conclusion: This study shows that the Mexameter
8.
9.
10.