全文获取类型
收费全文 | 1203篇 |
免费 | 62篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 20篇 |
儿科学 | 24篇 |
妇产科学 | 18篇 |
基础医学 | 134篇 |
口腔科学 | 10篇 |
临床医学 | 93篇 |
内科学 | 193篇 |
皮肤病学 | 37篇 |
神经病学 | 99篇 |
特种医学 | 120篇 |
外科学 | 156篇 |
综合类 | 45篇 |
一般理论 | 1篇 |
预防医学 | 32篇 |
眼科学 | 39篇 |
药学 | 112篇 |
中国医学 | 30篇 |
肿瘤学 | 109篇 |
出版年
2023年 | 6篇 |
2022年 | 10篇 |
2021年 | 32篇 |
2020年 | 7篇 |
2019年 | 16篇 |
2018年 | 30篇 |
2017年 | 17篇 |
2016年 | 20篇 |
2015年 | 33篇 |
2014年 | 26篇 |
2013年 | 42篇 |
2012年 | 63篇 |
2011年 | 75篇 |
2010年 | 62篇 |
2009年 | 58篇 |
2008年 | 55篇 |
2007年 | 50篇 |
2006年 | 70篇 |
2005年 | 53篇 |
2004年 | 82篇 |
2003年 | 57篇 |
2002年 | 56篇 |
2001年 | 29篇 |
2000年 | 33篇 |
1999年 | 24篇 |
1998年 | 29篇 |
1997年 | 28篇 |
1996年 | 28篇 |
1995年 | 34篇 |
1994年 | 18篇 |
1993年 | 7篇 |
1992年 | 5篇 |
1991年 | 6篇 |
1990年 | 5篇 |
1989年 | 19篇 |
1988年 | 12篇 |
1987年 | 10篇 |
1986年 | 11篇 |
1985年 | 3篇 |
1984年 | 8篇 |
1983年 | 8篇 |
1982年 | 3篇 |
1981年 | 6篇 |
1980年 | 7篇 |
1978年 | 4篇 |
1977年 | 4篇 |
1974年 | 2篇 |
1972年 | 2篇 |
1971年 | 2篇 |
1961年 | 1篇 |
排序方式: 共有1272条查询结果,搜索用时 15 毫秒
1.
2.
3.
Fontan conversion with arrhythmia surgery. 总被引:2,自引:0,他引:2
Woong-Han Kim Hong Gook Lim Jeong Ryul Lee Joon Ryang Rho Eun Jung Bae Chung Il Noh Yong Soo Yoon Yong Jin Kim 《European journal of cardio-thoracic surgery》2005,27(2):250-257
OBJECTIVE: Hemodynamic abnormalities and refractory atrial arrhythmias in patients late after the Fontan operation result in significant morbidity and mortality. We reviewed our experience with Fontan conversion and concomitant arrhythmia surgery. METHODS: Between January 1996 and February 2004, 16 patients underwent Fontan conversion and arrhythmia surgery. Mean age at the initial Fontan operation was 5.1+/-3.5 (range: 2-15) years and mean age at Fontan conversion was 17.0+/-5.8 (range: 6-30). The initial Fontan operations were atriopulmonary connections in 14 patients, extracardiac lateral tunnel in 1, and intracardiac lateral tunnel in 1. The types of arrhythmia included atrial flutter in 10 patients and atrial fibrillation in 3. Fontan conversion operation was performed with intracardiac lateral tunnel in 5 patients and extracardiac conduit in 11. Arrhythmia surgery included isthmus cryoablation in 10 patients and right-sided maze in 3. RESULTS: There has been no mortality. At Fontan conversion operation, 7 patients required permanent pacemaker. All patients have improved to New York Heart Association class I or II. With a mean follow-up of 26.9+/-30.6 (range:1-87) months, 16 patients had sinus rhythm, 2 patients had transient atrial flutter which was well controlled, and 2 patients required permanent pacemaker during follow-up. CONCLUSIONS: Fontan conversion with concomitant arrhythmia surgery and permanent pacemaker placement is safe, improves New York Heart Association functional class, and has a low incidence of recurrent arrhythmias. In most patients, concomitant permanent pacemakers are needed. 相似文献
4.
The first 150 words of the full text of this article appear below. Key points Coronary artery disease accounts for >30% ofdeaths in Western society. The diagnosis of myocardial infarctionshould be qualified by size, causation and time from occurrence. Mortalityis reduced by immediate or primary percutaneouscoronary intervention or thrombolysis within the first 24 hof onset of ST-segment elevation myocardial infarction. Strategiesto reduce platelet activation (glycoprotein IIb/IIIa receptorantagonists, or clopidogrel) are now recommended in the treatmentof high-risk non-ST-segment myocardial infarction/unstable angina. Elevatedserum troponins may be the result of non-ischaemic myocardialdamage, especially in critical illness.
Pathophysiology
Changes in the definition of terms relating to the diagnosisof myocardial infarction (MI) have evolved by better understandingof the pathophysiology culminating in the new term of acutecoronary syndrome (ACS). Figure 1 illustrates the processesthat occur in the development of an acute coronary event. 相似文献
5.
6.
7.
Berbaum KS; el-Khoury GY; Franken EA Jr; Kathol M; Montgomery WJ; Hesson W 《Radiology》1988,168(2):507-511
The effect of knowledge of localizing symptoms and signs in the detection of fractures was studied. Forty radiographs of the extremities were examined twice by seven radiologists; the sessions were separated by 4 months. In 26 cases, a subtle fracture was present; 14 cases were normal. In half of the cases at each session, the precise location of pain, tenderness, or swelling was provided. The observer was asked to determine if the case was normal or abnormal (provide the exact location of the fracture) and to indicate the degree of confidence in the diagnosis. Responses were converted to a numeric scale for analysis. Analysis of receiver operator characteristic parameters indicates that clues regarding location of trauma facilitate detection of fractures. The improvement is based largely on an increased true-positive rate without an increased false-positive rate, regardless of the decision criteria of the radiologist (overall willingness to "overread" or "underread"). This has direct clinical applicability and reinforces the plea of radiologists for precise clinical information. 相似文献
8.
I?Satish?RaoEmail author Anand?C?Loya KS?Ratnakar VR?Srinivasan 《BMC clinical pathology》2005,5(1):11
Background
Lymph node infarction is known to occur in association with many non-neoplastic and neoplastic conditions however its occurrence in association with DIC is not reported hitherto in the literature. 相似文献9.
J W Park S N Ma E S Song C H Song M R Chae B H Park R W Rho S D Park H R Kim 《Infection and immunity》1996,64(7):2873-2876
Vibrio vulnificus is an estuarine bacterium that causes septicemia and serious wound infection. Cytolysin produced by V. vulnificus has been incriminated as one of the important virulence determinants of bacterial infection. Cytolysin (8 hemolytic units) given intravenously to mice via their tail veins caused severe hemoconcentration and lethality. Cytolysin treatment greatly increased pulmonary wet weight and vascular permeability as measured by (125)I-labeled albumin leakage without affecting those factors of other organs significantly. Blood neutrophils were markedly decreased in number after cytolysin injection, with a concomitant increase in the level of pulmonary myeloperoxidase activity, indicating that cytolysin-induced neutropenia might be due to pulmonary sequestration of neutrophils. By microscopic examination, severe perivascular edema and neutrophil infiltration were evident in lung tissues. These results suggest that increased vascular permeability and neutrophil sequestration in the lungs are important factors in lethal activity by cytolysin. 相似文献
10.
Differentiation of human bone marrow cells into T lymphocytes by in vitro incubation with thymic extracts 总被引:9,自引:6,他引:9
下载免费PDF全文
![点击此处可从《Clinical and experimental immunology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
J. L. Touraine G. S. Incefy F. Touraine Y. M. Rho R. A. Good 《Clinical and experimental immunology》1974,17(1):151-158
Extracts of human or calf thymus influence differentiation of human bone marrow cells in vitro. Incubation of a putative stem cell fraction of human marrow with extracts of thymus for a period of 2 hr led to the appearance of lymphocytes with surface antigens recognized by a highly specific anti-T-cell antiserum. To a lesser degree, development of lymphocytes having the capacity to form rosettes with sheep erythrocytes was observed. Treatment of the so-called stem cell fraction with thymic extracts did not yield cells responsive to mitogenic influences of phyto-haemagglutinin or allogeneic cells. This model should permit further analyses of immunodeficiency diseases and provide a useful technique for purification and analysis of thymus extracts active with human haematopoietic cells. 相似文献