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A. M. Raschke A. E. C. Burger 《Archives of environmental contamination and toxicology》1997,32(1):42-49
A preliminary study undertaken by the CSIR in July 1993
on the health effects of aerial crop spraying of pesticides in the Vaalharts
irrigation area in South Africa indicated that potential health risks could
exist for the inhabitants of this area. An extensive scientific health risk
assessment and epidemiological study to determine the actual health risks, is
very expensive and requires medical and financial justification. The aim of
this study was to develop a theoretical health risk model, which could be
used as a predictive tool to determine as accurately as possible from the
data available if a complete scientific health risk assessment study is
justified. The actual amounts of pesticides sold in the Vaalharts area by two
major pesticide manufacturers were used to perform a theoretical health risk
assessment. The risks were assessed by making use of RISK*ASSISTANT, a
computer modeling system and chemical database. The United States
Environmental Protection Agency's (EPA) health risk model was applied to
the data to identify the hazards, assess the exposures and dose response, and
characterize the risks. Three exposure scenarios, namely, the ingestion of
food and water and the inhalation of air were evaluated. The method used to
calculate the risks varied according to the type of health hazard and the
results were characterized accordingly. The acute health effects due to
exposure to pesticides are well known and the risks are easy to determine.
However, the risks associated with chronic health hazards were more difficult
to calculate. For this reason a ranking model was developed which made use of
a point scoring system. This model highlights those pesticides which have the
greatest possibility of causing chronic health effects. From the results it
can be concluded that very large amounts of pesticides are used in the
Vaalharts area and that the community might be at risk to chronic health
effects. Although the theoretical health risk assessment model was
successfully used in this study, its effectiveness as a predictive tool still
has to be proven by a complete scientific study.
Received: April 1996/Revised: 21 July 1996 相似文献
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Hausegger KA; Cragg AH; Lammer J; Lafer M; Fluckiger F; Klein GE; Sternthal MH; Pilger E 《Radiology》1994,190(1):199
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Concern regarding the risk of disease transmission via blood transfusion together with periodic shortages of homologous blood has stimulated an interest in and the usage of autologous blood. Forty-nine patients had shed blood salvaged during venous thrombectomy. Between 200-3800 ml of blood were salvaged and reinfused using Solcotrans. No patient in this study required an homologous blood transfusion. The haematological parameters studied showed figures within the normal, acceptable range post-reinfusion. No patient experienced a clinical coagulopathy or showed evidence of renal dysfunction. The device is simple to use, safe and effective. 相似文献
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