全文获取类型
收费全文 | 2668篇 |
免费 | 147篇 |
国内免费 | 77篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 96篇 |
妇产科学 | 56篇 |
基础医学 | 312篇 |
口腔科学 | 62篇 |
临床医学 | 275篇 |
内科学 | 517篇 |
皮肤病学 | 61篇 |
神经病学 | 134篇 |
特种医学 | 369篇 |
外科学 | 274篇 |
综合类 | 66篇 |
预防医学 | 150篇 |
眼科学 | 73篇 |
药学 | 235篇 |
中国医学 | 13篇 |
肿瘤学 | 183篇 |
出版年
2023年 | 17篇 |
2022年 | 26篇 |
2021年 | 53篇 |
2020年 | 34篇 |
2019年 | 48篇 |
2018年 | 50篇 |
2017年 | 45篇 |
2016年 | 60篇 |
2015年 | 59篇 |
2014年 | 83篇 |
2013年 | 95篇 |
2012年 | 124篇 |
2011年 | 118篇 |
2010年 | 96篇 |
2009年 | 96篇 |
2008年 | 93篇 |
2007年 | 131篇 |
2006年 | 112篇 |
2005年 | 104篇 |
2004年 | 79篇 |
2003年 | 69篇 |
2002年 | 69篇 |
2001年 | 59篇 |
2000年 | 58篇 |
1999年 | 59篇 |
1998年 | 96篇 |
1997年 | 88篇 |
1996年 | 77篇 |
1995年 | 58篇 |
1994年 | 51篇 |
1993年 | 51篇 |
1992年 | 56篇 |
1991年 | 47篇 |
1990年 | 47篇 |
1989年 | 46篇 |
1988年 | 53篇 |
1987年 | 43篇 |
1986年 | 42篇 |
1985年 | 38篇 |
1984年 | 31篇 |
1983年 | 20篇 |
1982年 | 23篇 |
1981年 | 17篇 |
1980年 | 17篇 |
1979年 | 13篇 |
1978年 | 11篇 |
1977年 | 19篇 |
1976年 | 16篇 |
1975年 | 18篇 |
1972年 | 10篇 |
排序方式: 共有2892条查询结果,搜索用时 15 毫秒
1.
Krishna Pillai Javid Akhter Terence C. Chua Mena Shehata Nayef Alzahrani Issan Al-Alem David L. Morris 《Medicine》2015,94(9)
Thermal ablation of liver tumors near large blood vessels is affected by the cooling effect of blood flow, leading to incomplete ablation. Hence, we conducted a comparative investigation of heat sink effect in monopolar (MP) and bipolar (BP) radiofrequency ablation (RFA), and microwave (MW) ablation devices.With a perfused calf liver, the ablative performances (volume, mass, density, dimensions), with and without heat sink, were measured. Heat sink was present when the ablative tip of the probes were 8.0 mm close to a major hepatic vein and absent when >30 mm away. Temperatures (T1 and T2) on either side of the hepatic vein near the tip of the probes, heating probe temperature (T3), outlet perfusate temperature (T4), and ablation time were monitored.With or without heat sink, BP radiofrequency ablated a larger volume and mass, compared with MP RFA or MW ablation, with latter device producing the highest density of tissue ablated. MW ablation produced an ellipsoidal shape while radiofrequency devices produced spheres.Percentage heat sink effect in Bipolar radiofrequency : Mono-polar radiofrequency : Microwave was (Volume) 33:41:22; (mass) 23:56:34; (density) 9.0:26:18; and (relative elipscity) 5.8:12.9:1.3, indicating that BP and MW devices were less affected.Percentage heat sink effect on time (minutes) to reach maximum temperature (W) = 13.28:9.2:29.8; time at maximum temperature (X) is 87:66:16.66; temperature difference (Y) between the thermal probes (T3) and the temperature (T1 + T2)/2 on either side of the hepatic vessel was 100:87:20; and temperature difference between the (T1 + T2)/2 and temperature of outlet circulating solution (T4), Z was 20.33:30.23:37.5.MW and BP radiofrequencies were less affected by heat sink while MP RFA was the most affected. With a single ablation, BP radiofrequency ablated a larger volume and mass regardless of heat sink. 相似文献
2.
3.
4.
P Avalos-Peralta† A Herrera† JJ Ríos-Martín‡ AM Pérez-Bernal† D Moreno-Ramírez† F Camacho† 《Journal of the European Academy of Dermatology and Venereology》2006,20(1):79-83
We report the case of a patient with a 13-year history of pemphigus vulgaris (PV) treated with immunosuppressive agents, prednisone and mycophenolate mofetil who had developed lesions of Kaposi's sarcoma (KS) on a sole plaque of PV that had been previously treated with intralesional injections of steroids. The lesions were surgically removed and polymerase chain reaction (PCR) demonstrated human herpesvirus-8 (HHV-8) DNA. There were neither recurrences nor later dissemination of KS following gradual decrease of the immunosuppressive therapy. We suggest that the treatment with intralesional steroids may have influenced the local reactivation of a latent infection of the virus, determining the appearance of this localized KS. 相似文献
5.
CM Reid M. Nelson P. Beckinsale P. Ryan LMH Wing LJ Beilin MA Brown GLR Jennings CI Johnston J. Marley JJ McNeil TO Morgan J. Shaw ID Steven MJ West 《Clinical and experimental pharmacology & physiology》1997,24(5):370-373
1. The present study aimed to determine the feasibility of conducting a 5 year cardiovascular outcome trial of the treatment of 6000 elderly hypertensive patients in Australian general practices. 2. General practitioners (GPs) were invited to participate by mail and personal follow-up. Patient records were reviewed to identify subjects for a blood pressure (BP) screening programme. Blood pressure was measured on three occasions and eligible subjects were included if the average BP was 160 mmHg systolic or 90 mmHg diastolic if systolic BP was 140 mmHg. 3. Seven hundred and forty-one GPs were approached and 89 were enrolled in the study (12% of mail invites and 75% of those receiving a personal contact). In 16 practices where screening was completed, 82 000 records were reviewed to identify 4% patients eligible for screening. Twenty-two per cent of eligible subjects attended screening. Of 1938 subjects screened, 180 (9%) had BP 5=160/90 mmHg. Forty-seven percent of subjects (n = 916) were receiving antihypertensive therapy and 184 (20%) were withdrawn from therapy. One hundred and sixteen (63%) of these subjects had BP return to study entry levels within 6 weeks. Fifty-seven newly diagnosed and 81 previously treated subjects were randomized (7% of the screened population). 4. Based on the high participation rate of GPs, the response rate of patients to attend a BP screening programme and the 7% randomization to screening ratio for entry into the study, the ANBP2 pilot study has demonstrated that it is feasible to recruit subjects from Australian general practices to a cardiovascular outcome trial. 相似文献
6.
7.
We report a seven-year-old girl who presented with a sudden tumor apoplexy due to a parasagittal hemangiopericytoma. Following tumor excision, the child was noted to have bilateral optic nerve dysfunction and progressive papilledema, despite rapid overall neurological improvement. Based on the clinical features, we feel that this case represents an unusual form of visual deterioration related to impaired CSF absorption somehow precipitated by the acute tumour apoplexy. This unusual case of blindness responded significantly to CSF shunting. Several reports exist describing raised intracranial pressure with papilledema caused by nonthrombotic sinus occlusion due to tumors in proximity to the posterior superior sagittal sinus, torcular herophili and the jugular outlet. Communicating hydrocephalus, pseudotumor syndrome or intracranial venous sinus obstruction should be considered when otherwise inexplicable visual loss coexists with optic nerve dysfunction and papilledema. We emphasize the importance of a thorough search for the cause of visual loss. 相似文献
8.
9.
SUMMARY A young patient presenting with splenomegaly and hypersplenism was inadvertently found to have selective IgA deficiency. There were no symptoms of immunodeficiency and the patient responded well to splenectomy, with return of blood counts to normal without adverse effects. No other cause for the hypersplenism was found. We postulate selective IgA deficiency as a cause of splenomegaly and hypersplenism. 相似文献
10.