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Moamar Al-Jefout 《Middle East Fertility Society Journal》2011,16(3):167-174
Endometriosis is a chronic debilitating disease with features of chronic inflammation. Endometriosis is defined as the presence of endometrial like stroma and glands outside the uterine cavity (1). Medical professionals dealing with endometriosis face a lot of problems; in diagnosis, treatment and follow up of patients. Recent advances in molecular and clinical sciences offered a wide range of modalities for treatment. However, up to date there is no single very successful option for the ultimate treatment. In this review I have searched the literature using Medline, Pubmed, text books and other search engines to look for the most updated modalities for the treatment of endometriosis both surgical and medical ones. It seems to be that for fertility purposes surgical treatment followed by ART is the best available most beneficial way of dealing with endometriosis, while medical treatment is the best way to treat pain symptoms associated with endometriosis. 相似文献
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Moamar Al-Jefout Nedal Alnawaiseh Samer Yaghi Ameen Alqaisi 《Journal d'obstetrique et gynecologie du Canada》2018,40(2):165-170
Objective
This study sought to explore the prevalence and clinical manifestations of endometriosis in young women with chronic pelvic pain (CPP) refractory to conventional medical therapy.Methods
This prospective clinical interventional study was conducted in two general and private hospitals in the city of Al-Karak in Jordan. A total of 28 female patients aged ≤21 who had CPP refractory to conventional medical therapy were recruited during the years 2010–2014. The intervention used in the study was laparoscopy. Endometriosis was staged according to the American Society for Reproductive Medicine classification. The main outcome measures were the presence and stage of endometriosis at laparoscopy, the presence of cold intolerance, and the severity and duration of pain symptoms.Results
The mean age of participants was 18.4 (range 15 to 21). Endometriosis was found in 20 of 28 participants (71.4%), as follows: stage I, 9 of 20 (45.0%); stage II, 8 of 20 (40%); stage III, 2 of 21 (10%); and stage IV, 1 of 21 (5%). Notably, 16 of 28 (57.1%) of all participants reported cold intolerance, including 14 of 20 (70%) with endometriosis and 2 of 8 (25%) without endometriosis (Fisher exact [1-tail] P?=?0.039). There was no association between stage of disease and age distribution (≤18 and >19 to 21; P?=?0.7) or with duration of symptoms (≤2 and >2 years) and the presence of cold intolerance (P?>?0.05). However, severity of pain symptoms (<7 vs. ≥7, as measured by the visual analogue scale [VAS]) was associated significantly with stage of disease (P?=?0.011).Conclusion
The prevalence of endometriosis among young women with CPP refractory to conventional therapy was high, mainly in the mild stage. Cold intolerance was highly associated with endometriosis. 相似文献6.
Al-Jefout M Andreadis N Tokushige N Markham R Fraser I 《American journal of obstetrics and gynecology》2007,197(6):578-578.e4
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Al-Jefout M Palmer J Fraser IS 《The Australian & New Zealand journal of obstetrics & gynaecology》2007,47(3):247-249
Adolescent familial endometriosis may cause severe and persistent symptoms that are disruptive to lifestyle. Treatment may be difficult in many cases. We describe the novel and successful first use of a simultaneous combination of a levonorgestrel intrauterine system and an etonogestrel subdermal implant in a teenager with severe pain symptoms as a result of laparoscopically confirmed endometriosis, which was refractory to other treatments. 相似文献
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Lahoud R Kwik M Ryan J Al-Jefout M Foley J Illingworth P 《Archives of gynecology and obstetrics》2012,285(2):535-540
Objective
To assess the impact of pre-hCG elevated progesterone on live birth outcomes during GnRH agonist long down regulated protocol assisted reproduction cycles. 相似文献
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