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Neurological Sciences - The prevalence of osteoporosis is reported differently. We designed this systematic review and meta-analysis to estimate pooled prevalence of osteoporosis and osteopenia in...  相似文献   
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Neurological Sciences - The prevalence of COVID-19 is different in studies conducted in different countries. The aim of this systematic review and meta-analysis is to estimate the pooled prevalence...  相似文献   
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Journal of Neurology - Several studies report mixed associations between the retinal nerve fiber layer (RNFL) thickness with cognitive and physical disability in persons with multiple sclerosis...  相似文献   
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Background

Gender issues and the female preponderance in neuromyelitis optica spectrum disorder (NMOSD) have been investigated before, yet the interplay between NMOSD and menstrual characteristics has remained unknown. Thus, the aim was to compare menstrual cycle patterns and their symptoms in NMOSD patients and healthy women.

Methods

This cross-sectional study was conducted during 2015–2016 in Isfahan, Iran, and included female patients aged > 14 years with a diagnosis of NMOSD and healthy subjects as controls. Data regarding age at menarche, menstrual characteristics, history of premenstrual syndrome (PMS) and possible perimenstrual symptoms were collected. Also, NMOSD patients were asked to report changes in their menstrual cycles after onset of the disorder.

Results

The final study population included 32 NMOSD and 33 healthy controls. These groups did not differ regarding their demographics (P > 0.05), and age at menarche in the NMOSD and control groups was 13.31 ± 1.49 years and 13.48 ± 1.44 years, respectively (P = 0.637). The controls experienced PMS more frequently (78.8% vs. 40.6% in the NMOSD patients; P = 0.03), with no significant differences in other menstrual features between groups (P > 0.05). However, changes in menstruation after NMOSD onset were reported by 43.8% of patients, with an increase in menstrual irregularities from 15.6% to 43.7% (P = 0.012); other menstrual characteristics did not differ after disease onset (P > 0.05).

Conclusion

Menstruation do not differ between healthy controls and NMOSD patients before the onset of disease whereas, after its onset, those affected experienced more irregularities in their menstrual cycles. This may be an effect of NMOSD and its underlying disorders on menstruation and suggests that further interventions may be required for affected women.  相似文献   
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Neurological Sciences - Prevalence of multiple sclerosis (MS) is increasing world-wide. Iran is not exception. As the prevalence reported differently in various provinces, we designed this...  相似文献   
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Neurological Sciences - Patients with Parkinson’s disease (PD) are at higher risk of COVID-19 infection as most of them are at older age. The goal of this study is to update the pooled...  相似文献   
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A possible association between Bell''s palsy and COVID‐19 vaccination has been suggested previously. Here, we report two cases of facial nerve hemiparalysis following the Sputnik V COVID‐19 vaccination in a 27‐year‐old female patient and a 58‐year‐old male patient who were both clinically diagnosed with Bell''s palsy.  相似文献   
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