全文获取类型
收费全文 | 810篇 |
免费 | 49篇 |
国内免费 | 15篇 |
专业分类
儿科学 | 26篇 |
妇产科学 | 7篇 |
基础医学 | 55篇 |
口腔科学 | 16篇 |
临床医学 | 92篇 |
内科学 | 252篇 |
皮肤病学 | 6篇 |
神经病学 | 22篇 |
特种医学 | 196篇 |
外科学 | 51篇 |
综合类 | 40篇 |
预防医学 | 38篇 |
眼科学 | 4篇 |
药学 | 31篇 |
1篇 | |
肿瘤学 | 37篇 |
出版年
2023年 | 2篇 |
2022年 | 4篇 |
2021年 | 6篇 |
2020年 | 4篇 |
2019年 | 7篇 |
2018年 | 13篇 |
2017年 | 5篇 |
2016年 | 11篇 |
2015年 | 10篇 |
2014年 | 10篇 |
2013年 | 17篇 |
2012年 | 23篇 |
2011年 | 30篇 |
2010年 | 17篇 |
2009年 | 16篇 |
2008年 | 29篇 |
2007年 | 47篇 |
2006年 | 26篇 |
2005年 | 32篇 |
2004年 | 31篇 |
2003年 | 24篇 |
2002年 | 17篇 |
2001年 | 17篇 |
2000年 | 10篇 |
1999年 | 19篇 |
1998年 | 25篇 |
1997年 | 25篇 |
1996年 | 18篇 |
1995年 | 27篇 |
1994年 | 24篇 |
1993年 | 37篇 |
1992年 | 10篇 |
1991年 | 14篇 |
1990年 | 20篇 |
1989年 | 22篇 |
1988年 | 23篇 |
1987年 | 42篇 |
1986年 | 34篇 |
1985年 | 26篇 |
1984年 | 15篇 |
1983年 | 16篇 |
1982年 | 10篇 |
1981年 | 14篇 |
1980年 | 14篇 |
1979年 | 4篇 |
1978年 | 8篇 |
1977年 | 6篇 |
1976年 | 2篇 |
1975年 | 5篇 |
1973年 | 3篇 |
排序方式: 共有874条查询结果,搜索用时 15 毫秒
1.
G Marchesini G Forlani F Cerrelli R Manini S Natale L Baraldi G Ermini G Savorani D Zocchi N Melchionda 《Diabetic medicine》2004,21(4):383-387
AIMS: Different criteria have been proposed by the World Health Organization (WHO) and by the Third Report of the National Cholesterol Education Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATPIII) for the diagnosis of the metabolic syndrome. Its identification is of particular importance for coronary risk assessment. METHODS: The prevalence of the metabolic syndrome was determined according to the two different proposals in 1569 consecutive subjects with Type 2 diabetes. RESULTS: By the WHO proposal, 81% of cases (95% confidence interval, 79-83) were labelled as metabolic syndrome. Microalbuminuria had the highest specificity (99%) and visceral obesity the highest sensitivity (93%). Seventy-eight per cent of patients (95% CI, 76-80) fulfilled the ATPIII criteria for metabolic syndrome, low HDL-cholesterol having the highest specificity (95%), elevated blood pressure having the highest sensitivity. According to both proposals, 1113 patients were positive; 183 were concordantly negative, indicative of a fairly good agreement (k statistics, 0.464). Subjects only positive for the WHO proposal were more frequently males, had a lower BMI and a higher arterial pressure. Only subjects identified by the ATPIII proposal had a significantly higher prevalence of previously detected coronary heart disease. CONCLUSIONS: Minimum criteria for the metabolic syndrome are met in most patients with Type 2 diabetes. Correct identification of the syndrome is important for an integrated approach to reduce the high costs and the associated disabilities. The ATPIII proposal more clearly identifies the burden of coronary heart disease associated with the metabolic syndrome. 相似文献
2.
3.
4.
5.
Intestinal obstruction proximal to a transition zone without an interposed physical barrier usually indicates Hirschsprung disease. The authors report one case of focal small bowel muscular thinning just distal to a transition zone that produced clinical and radiographic findings that simulated long-segment Hirschsprung disease in a 2-day-old infant. 相似文献
6.
7.
Mutations in the retinal guanylate cyclase (RETGC-1) gene in dominant cone-rod dystrophy 总被引:3,自引:0,他引:3
Kelsell RE; Gregory-Evans K; Payne AM; Perrault I; Kaplan J; Yang RB; Garbers DL; Bird AC; Moore AT; Hunt DM 《Human molecular genetics》1998,7(7):1179-1184
The dominant cone-rod dystrophy gene CORD6 has previously been mapped to
within an 8 cM interval on chromosome 17p12-p13. The retinal- specific
guanylate cyclase gene (RETGC-1), which maps to within this genetic
interval and previously was implicated in Leber's congenital amaurosis, was
screened for mutations within this family and in a panel of small families
and individuals with various cone and cone- rod dystrophy phenotypes. A
missense mutation (E837D) was identified in affected members of the CORD6
family, as well as a second missense mutation (R838C) in three other
families with dominant cone-rod dystrophy. RETGC-1 is only the fourth gene
to be implicated in cone-rod dystrophy and this is the first report of
dominant mutations in this gene.
相似文献
8.
R. Bolzani G. P. Bianchi G. Marchesini E. Sarti 《Medical & biological engineering & computing》1990,28(4):325-328
A three-compartment model was used to analyse the urea response to an alanine infusion in control subjects and patients with
liver cirrhosis. Discriminant analysis showed a good separation between model coefficients of the two groups. A single parameter
was derived, able to quantify the liver functional capacity. The method provides a useful diagnostic tool in patients with
liver disease. 相似文献
9.
10.