全文获取类型
收费全文 | 2740篇 |
免费 | 340篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 38篇 |
儿科学 | 108篇 |
妇产科学 | 84篇 |
基础医学 | 652篇 |
口腔科学 | 57篇 |
临床医学 | 246篇 |
内科学 | 522篇 |
皮肤病学 | 24篇 |
神经病学 | 152篇 |
特种医学 | 197篇 |
外科学 | 289篇 |
综合类 | 131篇 |
一般理论 | 1篇 |
预防医学 | 172篇 |
眼科学 | 35篇 |
药学 | 170篇 |
中国医学 | 1篇 |
肿瘤学 | 213篇 |
出版年
2021年 | 30篇 |
2019年 | 31篇 |
2018年 | 34篇 |
2015年 | 32篇 |
2014年 | 51篇 |
2013年 | 69篇 |
2012年 | 106篇 |
2011年 | 99篇 |
2010年 | 71篇 |
2009年 | 83篇 |
2008年 | 122篇 |
2007年 | 99篇 |
2006年 | 96篇 |
2005年 | 91篇 |
2004年 | 86篇 |
2003年 | 97篇 |
2002年 | 85篇 |
2001年 | 79篇 |
2000年 | 67篇 |
1999年 | 76篇 |
1998年 | 61篇 |
1997年 | 72篇 |
1996年 | 73篇 |
1995年 | 53篇 |
1994年 | 46篇 |
1993年 | 60篇 |
1992年 | 60篇 |
1991年 | 55篇 |
1990年 | 51篇 |
1989年 | 54篇 |
1988年 | 60篇 |
1987年 | 61篇 |
1986年 | 60篇 |
1985年 | 56篇 |
1984年 | 37篇 |
1983年 | 47篇 |
1982年 | 51篇 |
1981年 | 30篇 |
1980年 | 30篇 |
1979年 | 38篇 |
1977年 | 31篇 |
1976年 | 28篇 |
1975年 | 30篇 |
1974年 | 27篇 |
1973年 | 29篇 |
1972年 | 43篇 |
1971年 | 28篇 |
1969年 | 27篇 |
1968年 | 25篇 |
1967年 | 32篇 |
排序方式: 共有3092条查询结果,搜索用时 15 毫秒
1.
D Gröne† R Treudler† EM de Villiers‡ R Husak† CE Orfanos† ChC Zouboulis†§ 《Journal of the European Academy of Dermatology and Venereology》2006,20(2):202-205
Cidofovir is an acyclic nucleoside phosphonate with broad-spectrum activity against DNA viruses, including human papilloma virus (HPV). However, data on the efficacy of cidofovir in an immunosuppressive setting remain contradictory. We report for the first time on the promotion of the healing of recalcitrant warts in a patient with myelodysplastic syndrome with intravenous cidofovir treatment. 相似文献
2.
D. M. Reid I. Mackay S. Wilkinson C. Miller D. G. Schuette J. Compston C. Cooper E. Duncan N. Galwey R. Keen B. Langdahl A. McLellan H. Pols A. Uitterlinden J. O’Riordan J. A. H. Wass S. H. Ralston S. T. Bennett 《Osteoporosis international》2006,17(1):125-132
Osteoporosis is a common disease with a strong genetic component characterized by reduced bone mass and an increased risk of fragility fractures. Bone mineral density (BMD) is the most important determinant of osteoporotic fracture risk, but the genes responsible for BMD regulation and fracture are incompletely defined. To enable multi-center studies to examine the genetic influences on BMD there is a requirement to standardize measurements across different manufacturers of bone densitometers, different versions of machines and different normative ranges. This paper describes a method developed to allow near-identical subjects with low age-adjusted BMD (based on Z-scores) to be recruited in 17 centers using 27 different densitometers. Cross-calibration was based on measurements using a European spine phantom circulated to all centers and measured ten times on each individual machine. From theses values an individual exponential curve, based on nominal versus observed BMD, was derived for each machine. As expected, there were large and significant variations in nominal BMD values, not only between scanners from different manufacturers but also between different versions of scanners from the same manufacturer. Hologic scanners tended to underestimate the nominal BMD, while Lunar scanners overestimated the value. Norland scanners gave mixed values over estimating BMD at the lower nominal value (0.5 g/cm2) while underestimating the value at the higher value (1.5 g/cm2). The validity of the exponential equations was tested using hip and spine measurements on 991 non-proband women from a familial osteoporosis study (FAMOS). After cross-calibration there was a considerable reduction in variation between machines. This observation, coupled with the absence of a similar reduction in variation attributable to a linear regression on age, demonstrated the validity of the cross-calibration approach. Use of the cross-calibration curves along with a standard normative range (in the case of this study, the Hologic normative range) allowed age-specific Z-scores to be used as an inclusion criterion in this genetic study, a method that will be useful for other trials where age-specific BMD inclusion criteria are required. 相似文献
3.
4.
5.
A D al-Haidary I G Mackay K D Bhoola N D Millar M L Watson J C Mackenzie 《Nephrology, dialysis, transplantation》1990,5(7):535-541
Eighteen renal transplant recipients and sixteen volunteers were subjected to the physiological manoeuvre of head-out water immersion, in order to compare changes in electrolyte and humoral responses known to occur in healthy individuals with those arising as a result of renal denervation in the transplant recipients. Although the tubular sodium response to water immersion was normal, tubular potassium excretion was markedly different in the transplant patients. Plasma values of atrial natriuretic factor increased in both groups and showed a close temporal relationship to urinary excretion of cyclic GMP. The attenuation in transplant recipients of the well-documented suppression of plasma renin activity during water immersion was probably due to a combination of factors, namely lack of renal innervation and an increase in circulating ANF. The small but significant increase in the excretion of enzymically active urinary kallikrein observed only in the transplant recipients during immersion still requires explanation. 相似文献
6.
7.
8.
A case of islet cell tumor occurring in a patient with the multiple endocrine neoplasia type I syndrome is reported. Immunostaining for insulin was strongly positive in the tumor cells. Numerous dense-core granules of endocrine caliber were identified ultrastructurally. Morphometric analysis of the secretory granules in 20 islet cell tumors gave a granule size of 182 +/- 52 nm (mean +/- standard deviation). 相似文献
9.
James E. Salter Jr. Donald Gibson Nelson G. Ord ez Bruce Mackay 《Ultrastructural pathology》1995,19(4):305-310
A 7-cm anterior mediastinal tumor in an 80-year-old woman was found by light and electron microscopy to be a neuroblastoma. Immunoreactivity for neuron-specific enolase, synaptophysin, and chromogranin supported the diagnosis. Neuroblastoma is an uncommon tumor in adults and we are not aware of a previous report of such a tumor in a patient of this age. 相似文献
10.