排序方式: 共有2条查询结果,搜索用时 15 毫秒
1
1.
MANOELLE KOSSOROTOFF CORALIE GONIN‐FLAMBOIS CYRIL GITIAUX SUSANA QUIJANO NATHALIE BODDAERT NADIA BAHI‐BUISSON CHRISTINE BARNERIAS OLIVIER DULAC FRANCIS BRUNELLE ISABELLE DESGUERRE 《Developmental medicine and child neurology》2010,52(7):626-631
Aim Posterior fossa strokes account for about 10% of ischaemic strokes in children. Although motor and dysautonomic symptoms are common, to our knowledge cognitive and affective deficits have not been described in the paediatric literature. Our aim, therefore, was to describe these symptoms and deficits. Method In a retrospective study, we included all cases of posterior fossa strokes in children occurring at a single centre between 2005 and 2007, and investigated cognitive and affective deficits. Results Five males aged 3 to 14 years met the inclusion criteria. They all presented very early with mood disturbances: outbursts of laughter and/or crying and alternating agitation or prostration that disappeared spontaneously within a few days. Persistent cognitive deficits were also diagnosed in all five: initial mutism, then anomia, followed by comprehension deficiency and deficiencies of planning ability, visual–spatial organization, and attention. Despite early and intensive rehabilitation, recovery from these cognitive deficits was slow and sometimes incomplete, and on follow‐up they proved to be more disabling than the motor symptoms. Interpretation These findings are similar to the cerebellar cognitive affective syndrome described in adults, and quite similar to the language and affective deficits observed in children after surgery for posterior fossa tumour. This is consistent with the role of the cerebellum and brainstem in affective and cognitive processes from early development. 相似文献
2.
CYRIL GITIAUX MANOELLE KOSSOROTOFF JEAN BERGOUNIOUX ELIAS ADJADJ FABRICE LESAGE NATHALIE BODDAERT MARIE HULLY DOMINIQUE BRUGEL ISABELLE DESGUERRE BRIGITTE BADER‐MEUNIER 《Developmental medicine and child neurology》2012,54(12):1160-1163
Kawasaki disease is an acute vasculitis, that has a classic complication of acquired coronary artery aneurysm. Severe forms with multi‐organ involvement or neurological dysfunction are rare. Cerebral vascular involvement has been related to large‐vessel injury or cardioembolism, leading to focal brain infarction. A 4‐year‐old female presented with unusual, rapidly catastrophic Kawasaki disease with refractory shock, acute renal failure, and coma, requiring intensive haemodynamic management. The observation of diffuse micro‐haemorrhages (T2*‐weighted sequence) associated with white matter injury on brain magnetic resonance imaging (MRI) pointed towards lesions of the medium/small blood vessels. Cerebral vasculitis was suspected and the immunosuppressive treatment was increased Subsequently, the patient’s recovery was rapid. On follow‐up severe, bilateral vitritis was evident and surgery improved visual outcome. Early recognition of severe or unusual forms of Kawasaki disease could lead to more favourable outcome using appropriate treatment strategies. Diffuse cerebral micro‐haemorrhages on T2* brain MRI sequences might be a key sign for the diagnosis of medium or small cerebral vessel involvement. 相似文献
1