全文获取类型
收费全文 | 19464篇 |
免费 | 1112篇 |
国内免费 | 81篇 |
专业分类
耳鼻咽喉 | 222篇 |
儿科学 | 524篇 |
妇产科学 | 481篇 |
基础医学 | 2517篇 |
口腔科学 | 728篇 |
临床医学 | 1660篇 |
内科学 | 4418篇 |
皮肤病学 | 451篇 |
神经病学 | 2133篇 |
特种医学 | 667篇 |
外国民族医学 | 3篇 |
外科学 | 2629篇 |
综合类 | 128篇 |
一般理论 | 4篇 |
预防医学 | 976篇 |
眼科学 | 340篇 |
药学 | 1277篇 |
中国医学 | 37篇 |
肿瘤学 | 1462篇 |
出版年
2023年 | 96篇 |
2022年 | 229篇 |
2021年 | 468篇 |
2020年 | 262篇 |
2019年 | 371篇 |
2018年 | 448篇 |
2017年 | 325篇 |
2016年 | 399篇 |
2015年 | 453篇 |
2014年 | 610篇 |
2013年 | 806篇 |
2012年 | 1267篇 |
2011年 | 1291篇 |
2010年 | 763篇 |
2009年 | 635篇 |
2008年 | 1124篇 |
2007年 | 1080篇 |
2006年 | 1098篇 |
2005年 | 1030篇 |
2004年 | 914篇 |
2003年 | 846篇 |
2002年 | 783篇 |
2001年 | 548篇 |
2000年 | 532篇 |
1999年 | 432篇 |
1998年 | 180篇 |
1997年 | 168篇 |
1996年 | 161篇 |
1995年 | 137篇 |
1994年 | 138篇 |
1993年 | 113篇 |
1992年 | 336篇 |
1991年 | 276篇 |
1990年 | 256篇 |
1989年 | 219篇 |
1988年 | 187篇 |
1987年 | 169篇 |
1986年 | 176篇 |
1985年 | 163篇 |
1984年 | 126篇 |
1983年 | 88篇 |
1982年 | 63篇 |
1981年 | 63篇 |
1980年 | 57篇 |
1979年 | 91篇 |
1978年 | 52篇 |
1977年 | 52篇 |
1974年 | 57篇 |
1972年 | 72篇 |
1971年 | 52篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Del Lama Rafael Silva Candido Raquel Mariana Chiari-Correia Natália Santana Nogueira-Barbosa Marcello Henrique de Azevedo-Marques Paulo Mazzoncini Tinós Renato 《Journal of digital imaging》2022,35(3):446-458
Journal of Digital Imaging - Vertebral Compression Fracture (VCF) occurs when the vertebral body partially collapses under the action of compressive forces. Non-traumatic VCFs can be secondary to... 相似文献
3.
4.
5.
María Cabrerizo Gloria Trallero María José Pena Amaia Cilla Gregoria Megias Carmen Mu?oz-Almagro Eva Del Amo Diana Roda Ana Isabel Mensalvas Antonio Moreno-Docón Juan García-Costa Nuria Rabella Manuel Ome?aca María Pilar Romero Sara Sanbonmatsu-Gámez Mercedes Pérez-Ruiz María José Santos-Mu?oz Cristina Calvo And the study group of “Enterovirus parechovirus infections in children under ?years-old Spain” PI- 《European journal of pediatrics》2015,174(11):1511-1516
6.
7.
Serum p55 and p75 tumour necrosis factor receptors as markers of disease activity in juvenile chronic arthritis. 总被引:4,自引:1,他引:3
下载免费PDF全文
![点击此处可从《Annals of the rheumatic diseases》网站下载免费的PDF全文](/ch/ext_images/free.gif)
M Gattorno P Picco A Buoncompagni F Stalla P Facchetti M P Sormani V Pistoia 《Annals of the rheumatic diseases》1996,55(4):243-247
OBJECTIVE: To determine the expression of tumour necrosis factor alpha (TNF alpha) and its soluble receptors (p55 and p75) in the sera and synovial fluid of patients with juvenile chronic arthritis (JCA), and their correlation with disease activity parameters. METHODS: Ninety eight sera from 45 patients with JCA (14 systemic, 12 polyarticular, 19 pauciarticular), 20 sera from age matched healthy controls, and five synovial fluids from five antinuclear antibody (ANA) positive pauciarticular JCA patients were tested for the presence of TNF alpha, soluble TNF receptors p55 and p75 (sTNFRp55, sTNFRp75), and interleukin-6 (IL-6) by an enzyme amplified sensitivity immunoassay. Physician global estimate of disease activity, weekly fever score and joint score, C reactive protein (CRP), erythrocyte sedimentation rate (ESR), and haemoglobin concentration were evaluated as parameters of disease activity. The expression of p55 and p75 on peripheral mononuclear cells (MNCs) from five patients with systemic JCA and synovial MNCs from five ANA positive patients with pauciarticular JCA was evaluated by flow cytometry. RESULTS: TNF alpha serum concentrations did not differ significantly between the patients with active JCA and the control group. No correlation was found between TNF alpha and parameters of disease activity, but both p55 and p75 showed a significant positive correlation with the physician global estimate of disease activity (p < 0.001), ESR (p < 0.001), CRP (p < 0.001), and serum concentrations of IL-6 (p < 0.001). Serum concentrations of haemoglobin correlated inversely with the concentrations of p55 and p75 (p < 0.001). Synovial lymphocytes selectively expressed the p75 surface receptor. CONCLUSIONS: sTNFRp55 and sTNFRp75 each represent a sensitive marker of disease activity in JCA. Their increased expression in biological fluids may support the hypothesis that TNF alpha has a role in the pathogenesis of JCA. 相似文献
8.
A. Giacometti O. Cirioni G. Greganti A. Fineo R. Ghiselli M. Del Prete F. Mocchegiani B. Fileni F. Caselli E. Petrelli V. Saba G. Scalise 《European journal of clinical microbiology & infectious diseases》2002,21(7):553-556
The in vitro activities of povidone iodine, potassium peroxymonosulfate, and dimethyldidecylammonium chloride were investigated
against 379 nosocomial isolates of Staphylococcus aureus and Pseudomonas aeruginosa responsible for surgical wound infections in patients operated on between July 1995 and June 2001. Overall, the isolates
were inhibited by the antiseptics at concentrations below those used routinely. In spite of increasing resistance to the various
antibiotics used to treat surgical wound infections, no significant variation in the susceptibility to antiseptics was demonstrated
during this 6-year study.
Electronic Publication 相似文献
9.
10.
D-dimer has proved a useful diagnostic tool for the exclusion of deep venous thrombosis (DVT). The objective of this paper was to evaluate the diagnostic performance of a diagnostic algorithm combining clinical probability and D-dimer in outpatients receiving oral anticoagulant treatment (OAT) similar to those regularly applied to nonanticoagulated individuals. We enrolled 70 outpatients on OAT who presented with clinically suspected DVT; a standard diagnostic algorithm including clinical evaluation using the modified Wells score and a quantitative immunoturbidimetric D-dimer assay (STA Liatest D-Di; Diagnostica Stago, Asniéres sur Seine, France) was used. A 3-month follow-up period was applied for those patients in whom DVT was initially excluded. The prevalence of DVT was 18.5% (13/70); four of the diagnoses were made during the 3-month follow-up period. The sensitivity, specificity and negative predictive value of D-dimer were 69.2% (95 confidence interval, 42.4-87.3), 47.4% (95% confidence interval, 35.0-60.1) and 87.1% (95% confidence interval, 71.1-94.9), respectively. In conclusion, D-dimer is of limited value in outpatients on OAT presenting with clinically suspected DVT and should be omitted in such individuals; these patients should always undergo compression venous ultrasound, and repeat ultrasonography within 1 week might be warranted in cases with an initial negative examination. 相似文献