全文获取类型
收费全文 | 1245篇 |
免费 | 91篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 25篇 |
妇产科学 | 18篇 |
基础医学 | 89篇 |
口腔科学 | 3篇 |
临床医学 | 92篇 |
内科学 | 309篇 |
皮肤病学 | 11篇 |
神经病学 | 69篇 |
特种医学 | 31篇 |
外科学 | 321篇 |
综合类 | 31篇 |
一般理论 | 1篇 |
预防医学 | 75篇 |
眼科学 | 31篇 |
药学 | 99篇 |
中国医学 | 13篇 |
肿瘤学 | 114篇 |
出版年
2024年 | 2篇 |
2023年 | 17篇 |
2022年 | 52篇 |
2021年 | 63篇 |
2020年 | 43篇 |
2019年 | 52篇 |
2018年 | 89篇 |
2017年 | 61篇 |
2016年 | 54篇 |
2015年 | 43篇 |
2014年 | 63篇 |
2013年 | 62篇 |
2012年 | 101篇 |
2011年 | 100篇 |
2010年 | 49篇 |
2009年 | 43篇 |
2008年 | 89篇 |
2007年 | 63篇 |
2006年 | 60篇 |
2005年 | 66篇 |
2004年 | 44篇 |
2003年 | 41篇 |
2002年 | 28篇 |
2001年 | 8篇 |
2000年 | 13篇 |
1999年 | 5篇 |
1998年 | 6篇 |
1997年 | 1篇 |
1996年 | 3篇 |
1995年 | 1篇 |
1994年 | 3篇 |
1993年 | 3篇 |
1992年 | 2篇 |
1991年 | 2篇 |
1988年 | 2篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1981年 | 4篇 |
1980年 | 3篇 |
1976年 | 1篇 |
1969年 | 2篇 |
排序方式: 共有1346条查询结果,搜索用时 15 毫秒
1.
2.
Normal cerebral perfusion measurements using arterial spin labeling: reproducibility, stability, and age and gender effects. 总被引:4,自引:0,他引:4
Laura M Parkes Waqar Rashid Declan T Chard Paul S Tofts 《Magnetic resonance in medicine》2004,51(4):736-743
Before meaningful conclusions can be drawn from clinical measures of cerebral blood perfusion, the precision of the measurement must be determined and set in the context of inter- and intrasubject sources of variability. This work establishes the reproducibility of perfusion measurements using the noninvasive MRI technique of continuous arterial spin labeling (CASL). Perfusion was measured in 34 healthy normal subjects. Intersubject variability was assessed, and age and gender contributions were estimated. Intersubject variation was found to be large, with up to 100% perfusion difference for subjects of the same age and gender. Repeated measurements in one subject showed that perfusion remains remarkably stable in the short term when compared with intersubject variation and the large capacity for perfusion change in the brain. A significant decrease in the ratio of gray-matter to white-matter perfusion was found with increasing age (0.79% per year (P < 0.0005)). This appears to be due mainly to a reduction in gray-matter perfusion, which was found to decrease by 0.45% per year (P = 0.04). Regional analysis suggested that the gray-matter age-related changes were predominantly localized in the frontal cortex. Whole-brain perfusion was 13% higher (P = 0.02) in females compared to males. 相似文献
3.
Hassan Chamsi-Pasha Alaa Abdulmoneim Waqar H Ahmed Khaled F Al-Shaibi Aref Ajam Hassan Bakhamees Abdullah K Ashmeg 《Journal of the American Society of Echocardiography》2004,17(1):70-72
A 24-year-old man presented with a 24-hour history of pain and numbness in his left arm. The patient's clinical presentation of peripheral embolism was corroborated by angiography. Echocardiographic study showed masses in both right and left atria. Pathologic specimen from the embolus confirmed the diagnosis of aspergillosis. 相似文献
4.
Session XII Male contraception 相似文献
5.
6.
7.
Polymorphisms in interleukin -2, -6, and -10 are not associated with gastric cardia or esophageal cancer in a high-risk chinese population. 总被引:7,自引:0,他引:7
8.
9.
Muhammad Kashif Ashfaq Ahmad Muhammad Ali Mohseni Bandpei Maryam Farooq Humaira Iram Rida e Fatima 《Medicine》2022,101(31)
Background:Virtual reality (VR) is an advanced technique used in physical rehabilitation of neurological disorders, however the effects of VR on balance, gait, and motor function in people with Parkinson’s (PD) are still debated. Therefore, the systematic review aimed to determine the role of VR on motor function, balance and gait in PD patients.Methods:A comprehensive search to identify similar randomised controlled trials was conducted targeting 5 databases including Web of Science, PubMed, CINHAL, Cochrane Library, and Physiotherapy Evidence Database. A total of 25 studies were found eligible for this systematic review, and the methodological assessment of the quality rating of the studies was accomplished using the physiotherapy evidence database scale by 2 authors.Results:Out of the 25 included studies, 14 studies reported on balance as the primary outcome, 9 studies were conducted to assess motor function, and 12 assessed gait as the primary outcome. Most studies used the Unified Parkinson disease rating scale UPDRS (part-III) for evaluating motor function and the Berg Balance Scale as primary outcome measure for assessing balance. A total of 24 trials were conducted in clinical settings, and only 1 study was home-based VR trainings. Out of 9 studies on motor function, 6 reported equal improvement of motor function as compared to other groups. In addition, VR groups also revealed superior results in improving static balance among patient with PD.Conclusion:This systemic review found that the use of VR resulted in substantial improvements in balance, gait, and motor skills in patients with PD when compared to traditional physical therapy exercises or in combination with treatments other than physical therapy. Moreover, VR can be used as a supportive method for physical rehabilitation in patients of PD. However, the majority of published studies were of fair and good quality, suggesting a demand for high quality research in this area. 相似文献
10.
Shahin Shah Khan Irfan Ullah Shah Zada Aftab Ahmad Waqar Ahmad Haijun Xu Sadeeq Ullah Luo Liu 《Materials》2022,15(14)
The use of medical devices for therapeutic and diagnostic purpose is globally increasing; however, bacterial colonization on therapeutic devices can occur, causing severe infections in the human body. It has become an issue for public health. It is necessary to develop a nanomaterial based on photothermal treatment to kill toxic bacterial strains. Appropriately, high photothermal conversion and low-cost powerful photothermal agents have been investigated. Recently, gold nanocomposites have attracted great interest in biological applications. Here, we prepared rod-shaped Se-Te@Au nanocomposites of about 200 nm with uniform shape and surface-coated with gold nanoparticles for the first time showing high anti-bacterial and anti-cancer activities. Se-Te@Au showed proper structural consistency and natural resistance to bacterial and cancer cells. The strong absorption and high photothermal conversion efficacy made it a good photothermal agent material for the photothermal treatment of bacterial and cancer cells. The Se-Te@Au rod showed excellent anti-bacterial efficacy against Gram-negative Escherichia coli and Gram-positive Staphylococcus aureus, with highest recorded inhibition zones of 25 ± 2 mm and 22 ± 2 mm, respectively. More than 99% of both types of strains were killed after 5 min with a near-infrared (NIR) laser at the very low concentration of 48 µg/mL. The Se-Te@Au rod’s explosion in HeLa cells was extensively repressed and demonstrated high toxicity at 100 µg/mL for 5 min when subjected to an NIR laser. As a result of its high photothermal characteristics, the exceptional anti-bacterial and anti-cancer effects of the Se-Te@Au rod are considerably better than those of other methods previously published in articles. This study could open a new framework for sterilization applications on the industrial level. 相似文献