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排序方式: 共有433条查询结果,搜索用时 15 毫秒
1.
Y. O’Meara A. Green M. Carmody G. Doyle J. Donohoe 《Irish journal of medical science》1989,158(12):300-303
Twenty five patients with renal vasculitis presenting over an eight year period were reviewed. Ten had microscopic polyarteritis,
6 classic polyarteritis, 5 overlap syndrome, 2 Churg-Strauss syndrome and 2 Wegener’s granulomatosis. Clinical features included
hypertension, pulmonary involvement, neurological involvement and arthralgia. Serum creatinine was over 500 umol/1 in 13 patients,
10 of whom required dialysis. Visceral angiography was positive in 80% of those studied, Focal and segmental necrotising glomerulonephritis
was the commonest renal lesion. Treatment consisted of corticosteroids and cytotoxic agents in most cases. Plasmapheresis
was used for rapidly progressive renal failure, severe pulmonary haemorrhage or cerebral vasculitis. Improvement or stabilisation
of renal function was seen in 68% of patients treated. There were 4 early deaths and one late death. The diagnosis, histology,
treatment and outcome of renal vasculitis is discussed. The importance of early diagnosis and treatment is emphasised in this
potentially reversible cause of acute renal failure. 相似文献
2.
J T Kemshead J Treleaven L Heath A O Meara A Gee J Ugelstad 《Bone marrow transplantation》1987,2(2):133-139
The use of a panel of monoclonal antibodies and anti-mouse immunoglobulin-coated microspheres is described for the depletion of leukaemic blasts from bone marrow. Marrow treated in this way rapidly reconstitutes haemopoietic function after high-dose consolidation chemoradiotherapy. The recovery of cells from bone marrow is similar but not identical to results obtained on removal of neuroblasts from marrow to be used for autologous transplant. This is probably a reflection of the cross-reactivity of 'anti-leukaemic' antibodies with a variety of haemopoietic progenitor cells. The study described here demonstrates the feasibility of using this method to purge leukaemic cells from bone marrow. A much larger randomised study between patients receiving either purged or non-purged bone marrow would be necessary to validate the need to remove small numbers of tumour cells from bone marrow. 相似文献
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Aims/hypothesis
Foot ulcers in people with diabetes are a common and serious global health issue. Dressings form a key part of ulcer treatment. Existing systematic reviews are limited by the lack of head-to-head comparisons of alternative dressings in a field where there are several different dressing options. We aimed to determine the relative effects of alternative wound dressings on the healing of diabetic foot ulcers. 相似文献7.
Noelle B. Smith Ashton M. Steele Meara L. Weitzman Ana F. Trueba Alicia E. Meuret 《Archives of Suicide Research》2013,17(1):60-74
Self-directed disgust, a component of self-criticism, may present an important, yet unexplored emotion in the context of nonsuicidal self-injury (NSSI). The aim of this study was to examine the role of self-disgust in NSSI, specifically as a potential mediator in the relations between depression and NSSI as well as sexual abuse and NSSI, and to also better understand characteristics that might differentiate recent and past self-injurers. A total of 549 college students completed measures assessing NSSI, self-disgust, depression, anxiety sensitivity, and physical and sexual abuse. Results indicated self-disgust fully mediated the relation between depressive symptoms and NSSI status and partially mediated the relation between sexual abuse and NSSI status. Additionally, compared to past self-injurers (4.6%; n = 25), recent self-injurers (6.4%; n = 35) endorsed significantly higher self-disgust and depressive symptoms. Self-disgust may be an important component in NSSI and should be addressed in treatment. 相似文献
8.
A review of the invasive mosquitoes in Europe: ecology, public health risks, and control options 总被引:1,自引:0,他引:1
Medlock JM Hansford KM Schaffner F Versteirt V Hendrickx G Zeller H Van Bortel W 《Vector borne and zoonotic diseases (Larchmont, N.Y.)》2012,12(6):435-447
There has been growing interest in Europe in recent years in the establishment and spread of invasive mosquitoes, notably the incursion of Aedes albopictus through the international trade in used tires and lucky bamboo, with onward spread within Europe through ground transport. More recently, five other non-European aedine mosquito species have been found in Europe, and in some cases populations have established locally and are spreading. Concerns have been raised about the involvement of these mosquito species in transmission cycles of pathogens of public health importance, and these concerns were borne out following the outbreak of chikungunya fever in Italy in 2007, and subsequent autochthonous cases of dengue fever in France and Croatia in 2010. This article reviews current understanding of all exotic (five introduced invasive and one intercepted) aedine species in Europe, highlighting the known import pathways, biotic and abiotic constraints for establishment, control strategies, and public health significance, and encourages Europe-wide surveillance for invasive mosquitoes. 相似文献
9.
Lars E. Hagander Christopher D. Hughes Katherine Nash Karan Ganjawalla Allison Linden Yolanda Martins Kathleen M. Casey John G. Meara 《World journal of surgery》2013,37(1):14-23
Background
The critical shortage of surgeons in many low- and middle-income countries (LMICs) prevents adequate responses to surgical needs, but the factors that affect surgeon migration have remained incompletely understood. The goal of this study was to examine the importance of personal, professional, and infrastructural factors on surgeon migration from LMICs to the United States. We hypothesized that the main drivers of surgeon migration can be addressed by providing adequate domestic surgical infrastructure, surgical training programs, and viable surgical career paths.Methods
We conducted an internet-based nationwide survey of surgeons living in the US who originated from LMICs.Results
66 surgeons completed the survey. The most influential factors for primary migration were related to professional reasons (p ≤ 0.001). Nonprofessional factors, such as concern for remuneration, family, and security were significantly less important for the initial migration decisions, but adopted a more substantial role in deciding whether or not to return after training in the United States. Migration to the United States was initially considered temporary (44 %), and a majority of the surveyed surgeons have returned to their source countries in some capacity (56 %), often on multiple occasions (80 %), to contribute to clinical work, research, and education.Conclusions
This study suggests that surgically oriented medical graduates from LMICs migrate primarily for professional reasons. Initiatives to improve specialist education and surgical infrastructure in LMICs have the potential to promote retention of the surgical workforce. There may be formal ways for LMICs to gain from the international pool of relocated surgeons. 相似文献10.
Christopher D. Hughes Craig D. McClain Lars Hagander Jean Hamiltong Pierre Reinou S. Groen Adam L. Kushner John G. Meara 《World journal of surgery》2013,37(7):1526-1529