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Agata Cieślik-Bielecka Paweł Reichert Rafał Skowroński Tomasz Bielecki 《Platelets》2019,30(6):728-736
The current literature suggests that the antibacterial effect of leukocyte- and platelet-rich plasma (L-PRP) is directly related to platelet and leukocyte concentrations. The aim of this study was twofold: first, to evaluate the antimicrobial effect of L-PRP against selected bacterial strains in vitro, and second, to correlate this effect with leukocyte and platelet content in the final concentration. Blood was collected from 20 healthy males, and L-PRP, acellular plasma (AP), and autologous thrombin were consecutively prepared. Flow cytometry analysis of the blood, L-PRP, and AP was performed. The L-PRP gel, liquid L-PRP, and thrombin samples were tested in vitro for their antibacterial properties against seven selected bacterial strains using the Kirby–Bauer disk-diffusion method. There was notable antimicrobial activity against selected bacterial strains. No statistically significant correlations between antimicrobial activities and the platelet concentration in L-PRP were observed. Statistically significant positive correlations between selected leukocyte subtypes and antimicrobial activity were noted. A negative correlation was found between elevated monocyte count and antimicrobial activity of L-PRP against one bacterial strain studied. L-PRP possesses antimicrobial activity and can be potentially useful in the fight against certain postoperative infections. The bactericidal effect of L-PRP is caused by leukocytes, and there exists a relationship among selected leukocyte subtypes and L-PRP antimicrobial activity. 相似文献
3.
Oliver Sartor MD Daniel Heinrich MD Neil Mariados MD Maria José Méndez Vidal MD Daniel Keizman MD Camilla Thellenberg Karlsson MD Avivit Peer MD Giuseppe Procopio MD Stephen J. Frank MD Kalevi Pulkkanen MD Eli Rosenbaum MD Stefano Severi MD José Trigo MD Lucia Trandafir MD Volker Wagner MD Rui Li MS Luke T. Nordquist MD 《The Prostate》2019,79(14):1683-1691
4.
Doing it right the first time: quality improvement and the contaminant blood culture. 总被引:5,自引:3,他引:2 下载免费PDF全文
F I Weinbaum S Lavie M Danek D Sixsmith G F Heinrich S S Mills 《Journal of clinical microbiology》1997,35(3):563-565
The aim of the project was to determine whether the rate of contaminant blood cultures could be reduced by using a team of dedicated phlebotomists. Comparisons were made between adult patients requiring blood cultures for suspected bacteremia on medical and surgical units before and after the introduction and withdrawal of a dedicated blood culture team. The results showed that a significant reduction in the contaminant blood culture rate was achieved by the blood culture team (P < 0.001; chi(2) test). Therefore, in our experience, the rate of contaminant blood cultures can be reduced in a teaching hospital by using a team of dedicated phlebotomists. Calculations made with our data and those published by others suggest that cost savings from reducing false-positive blood cultures are greater than the cost of the blood culture team. 相似文献
5.
Heinrich Többen 《International journal of legal medicine》1940,34(1-3):186-208
Ohne ZusammenfassungReferat.HerrBuhtz-Breslau berichtet über den Fall Wolff-Breslau. Die klar überlegte Mordtat des frühreifen Jugendlichen hatte den Anlaß zu dem Gesetz über jugendliche Schwerverbrecher gebildet.HerrRücker-Hamburg berichtet über einen Arzt, der das Opfer einer Hysterica geworden war. Bei einer erregten Auseinandersetzung hatte er die Frau mit dem ihr entrissenen und gegen ihn gezückten Dolch niedergestoßen und getötet. Der Täter hatte 18 Jahre unter fremdem Namen in China das große Hospital einer deutsch-evangelischen Mission geleitet. Nach Verurteilung zu 2 Jahren Gefängnis und erlangter Bewährungsfrist ist er nach China zurückgekehrt. 相似文献
6.
Ferdinand Heinrich Koss 《Journal of molecular medicine (Berlin, Germany)》1938,17(44):1537-1538
Ohne Zusammenfassung 相似文献
7.
Philipp Pohlenz Marco Blessmann Felix Blake Sven Heinrich Rainer Schmelzle Max Heiland 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,103(3):412-417
OBJECTIVES: Intraoperative cone-beam computerized tomography (CBCT) imaging has been introduced in oral and maxillofacial surgery. Using midfacial fractures as the pioneer model, this study describes the spectrum of further promising clinical indications for intraoperative CBCT and a clinical combination with intraoperative navigation. STUDY DESIGN: One hundred seventy-nine patients admitted for surgical treatment of the facial skeleton were included in the study. Intraoperatively, 3-dimensional images were generated with the mobile CBCT scanner Arcadis Orbic 3D, obtained from Siemens Medical Solutions, in a variety of indications. RESULTS: The acquisition of the data sets was uncomplicated, and image quality was sufficient to assess the postoperative result in all cases. In the example of a facial gunshot injury, a navigation system for intraoperative localization of the metal foreign bodies was used. 相似文献
8.
Dr. Heinrich Schum 《Virchows Archiv : an international journal of pathology》1914,218(3):300-350
Ohne Zusammenfassungfrüherem Assistenten des Instituts, jetzigem Assistenten an der chirurgischen Abteilung des Augusta-Hospitals, Berlin.Hierzu Taf. IV und 1 Textfigur. 相似文献
9.
Ohne Zusammenfassung 相似文献
10.
W D Lehmann H C Heinrich R Leonhardt D P Agarwal H W Goedde J Kneer D Rating 《Alcohol》1986,3(4):227-231
Four normal and five aldehyde dehydrogenase (ALDH) isozyme I deficient individuals were subsequently loaded with (1-13C)ethanol and (1-13C)sodium acetate and the conversion of the label to 13CO2 was determined in expired air by isotope ratio mass spectrometry. In the 13C-acetate breath test, both groups showed virtually identical recovery of the label in expired air, namely 48.5 +/- 2.3% (mean +/- S.D.) for normal and 46.8 +/- 5.7% for deficient individuals. However, in the 13C-ethanol breath test, both the groups performed differently. On average, although a certain overlap of the single data was observed, the recovery of the label after four hours was 43.4 +/- 3.8% for the normal and 35.6 +/- 6.8% for the ALDH deficient subjects. These findings suggest a slower conversion of ethanol to carbon dioxide in aldehyde dehydrogenase deficient individuals, which may be another consequence of this deficiency besides the higher plasma acetaldehyde levels observed after ethanol loading in comparison to individuals with normal aldehyde dehydrogenase activity. 相似文献