全文获取类型
收费全文 | 1877篇 |
免费 | 220篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 10篇 |
儿科学 | 50篇 |
妇产科学 | 115篇 |
基础医学 | 63篇 |
口腔科学 | 97篇 |
临床医学 | 258篇 |
内科学 | 369篇 |
皮肤病学 | 63篇 |
神经病学 | 278篇 |
特种医学 | 23篇 |
外科学 | 496篇 |
综合类 | 4篇 |
预防医学 | 64篇 |
眼科学 | 10篇 |
药学 | 42篇 |
中国医学 | 1篇 |
肿瘤学 | 157篇 |
出版年
2023年 | 26篇 |
2022年 | 11篇 |
2021年 | 36篇 |
2020年 | 27篇 |
2019年 | 20篇 |
2018年 | 39篇 |
2017年 | 35篇 |
2016年 | 59篇 |
2015年 | 80篇 |
2014年 | 100篇 |
2013年 | 98篇 |
2012年 | 58篇 |
2011年 | 67篇 |
2010年 | 90篇 |
2009年 | 205篇 |
2008年 | 73篇 |
2007年 | 95篇 |
2006年 | 66篇 |
2005年 | 35篇 |
2004年 | 42篇 |
2003年 | 46篇 |
2002年 | 16篇 |
2001年 | 32篇 |
2000年 | 44篇 |
1999年 | 39篇 |
1998年 | 57篇 |
1997年 | 73篇 |
1996年 | 63篇 |
1995年 | 46篇 |
1994年 | 49篇 |
1993年 | 23篇 |
1992年 | 14篇 |
1991年 | 28篇 |
1990年 | 24篇 |
1989年 | 23篇 |
1988年 | 14篇 |
1987年 | 10篇 |
1986年 | 26篇 |
1985年 | 12篇 |
1984年 | 16篇 |
1983年 | 5篇 |
1982年 | 5篇 |
1978年 | 4篇 |
1963年 | 4篇 |
1959年 | 8篇 |
1958年 | 33篇 |
1957年 | 22篇 |
1956年 | 22篇 |
1955年 | 21篇 |
1954年 | 25篇 |
排序方式: 共有2100条查询结果,搜索用时 15 毫秒
1.
2.
HOCK LEONG EE MBBS MRCP CHEE LEOK GOH MBBS FRCP KHOO ES-Y. CHAN PHD POR ANG MBBS MRCP 《Dermatologic surgery》2006,32(1):34-40
BACKGROUND: Acquired bilateral nevus of Ota-like macules (Hori's nevus) is a common dyschromatosis among Asian women. Q-switched lasers have been used successfully as a treatment modality. OBJECTIVE: The purpose of this study was to compare the efficacy of using the Q-switched 532 nm neodymium:yttrium-aluminum-garnet (Nd:YAG) laser followed by the 1,064 nm laser versus the Q-switched 1,064 nm Nd:YAG laser alone in the treatment of Hori's nevus. METHODS: This is a prospective left-right comparative study. Ten women with bilateral Hori's nevus were recruited and treated with a combination of the Q-switched 532 and 1,064 nm Nd:YAG lasers on the right cheek and the Q-switched 1,064 nm Nd:YAG laser alone on the left cheek. Only one laser treatment session was performed. The degree of pigmentation was objectively recorded with a mexameter. Subjective assessment was made by both patients and two blinded, nontreating dermatologists. RESULTS: At 6 months, there was a statistically significant difference (p = .009) of 35.10 points using objective mexameter measurements between the two sides, favoring the side treated with a combination of 532 and 1,064 nm laser treatment. Subjective grading by the patients and blinded dermatologists also confirmed that combination therapy was more successful after one treatment. Although combination treatment had a higher incidence of mild postinflammatory changes, this disappeared within 2 months. CONCLUSIONS: Concurrent use of the Q-switched 532 nm Nd:YAG laser in combination with the 1,064 nm laser is more effective in pigment clearance than the Q-switched 1,064 nm Nd:YAG laser alone for Hori's nevi. 相似文献
3.
4.
MASAHIKO NAKASONO MITSUYOSHI HIROKAWA NAOKI MUGURUMA SEISUKE OKAMURA SUSUMU ITO MICHIYO OKAZAKI TAKAHIRO HORIE MASUO KIMURA MAYUKO TAKEUCHI TOSHI INOSHITA TOSHIAKI SANO 《Journal of gastroenterology and hepatology》2006,21(1):79-83
Background and Aim: Duodenal lymphangitis carcinomatosa has been sporadically described, but so far little attention has been paid to duodenal lymphangitis carcinomatosa. Methods: Four cases with duodenal lymphangitis carcinomatosa were endoscopically and histologically examined. Results: The four cases exhibited multiple polypoid lesions along the Kerckring's folds and/or were covered by characteristically granular, non‐ulcerated mucosa upon thickening. The granularity seems to been caused by dilated lymph vessels containing the carcinoma cells. The lesions were microscopically characterized by: (i) involvement of lymph vessels located in the upper portion of the lamina propria; (ii) no inflammatory changes; and (iii) no desmoplastic changes. Primary sites were thought to be the stomach in case 1, the pancreas in cases 2 and 4, and unknown in case 3. All patients died within 6 months after admission or endoscopic examination. Conclusions: As duodenal lymphangitis carcinomatosis shows characteristic endoscopic appearance, endoscopic diagnosis is not difficult. We should realize that the lesion represents extremely poor prognosis, and it should be distinguished from ordinary metastatic duodenal carcinoma. 相似文献
5.
CACILDA S. SOUZA MD PHD ANA B. S. NEVES LÍLIA A. B. FELÍCIO MD JULIANA FERREIRA MD CRISTINA KURACHI MD PHD VANDERLEI S. BAGNATO MD PHD 《Dermatologic surgery》2007,33(2):194-198
BACKGROUND: The thickness and depth of invasion of skin tumors may be limiting factors for topical photosensitizer-based photodynamic therapy (PDT). The use of PDT with systemic photosensitizer needs to be further explored as a modality of treatment for nonmelanoma skin cancer (NMSC). OBJECTIVE: The objective was to present six patients with multiple, nodular, and/or pigmented NMSC treated successfully with purified hematoporphyrin derivative (PHD) and PDT using prior debulking. METHODS: After 24 hours of systemic PHD (1.5 mg/kg), 12 lesions of NMSC were selected for PHD-PDT alone and 6 nodular/elevated lesions for PHD-PDT following a debulking procedure. The tumor area was illuminated in one single-dose session of 300 J/cm(2), at an intensity range of 130 to 150 mW/cm(2), with a 630-nm-wavelength diode laser. RESULTS: The prior curettage provided significant reduction in volume and/or pigmentation of lesions. After the session of PHD-PDT with prior curettage and additional topical 20% ALA-PDT in two lesions or PHD-PDT alone, 83% (5/6) of lesions and 58% (7/12) of lesions, respectively, maintained a complete clinical response, 22.2+/-8.9 months of follow-up. CONCLUSIONS: The combination of prior debulking with systemic agents-PDT appears to be a good option for multiple, pigmented, and/or nodular lesions of NMSC and can allow the improvement of clinical results. 相似文献
6.
7.
8.
LISA HARNACK DrPH RD GLADYS BLOCK PHD AMY SUBAR PhD RD SYLVIA LANE PhD RICHARD BRAND PhD 《Journal of the American Dietetic Association》1997,97(9):957-965
Objective To examine the relationship of cancer prevention-related nutrition knowledge, beliefs, and attitudes to cancer prevention dietary behavior.Subjects/setting Noninstitutionalized US adults aged 18 years and older.Methods Data collected in the 1992 National Health Interview Survey Cancer Epidemiology Supplement were analyzed. The supplement included questions to ascertain knowledge, beliefs, and attitudes and a food frequency questionnaire to ascertain nutrient intake.Statistics Multivariate linear regression modeling was conducted to assess the hypothesized relationships.Results After adjustment for relevant covariates (age, sex, education, total energy, perceived barriers to eating a more healthful diet), knowledge and belief constructs were predictive of dietary behavior. Specifically, fat, fiber, and fruit and vegetable intakes more closely approximated dietary recommendations for persons with more cancer-prevention knowledge. The strength of the associations between these constructs and dietary behavior varied in some cases according to level of education and perceived barriers to eating a healthful diet. Of the perceived barriers to eating a healthful diet, perceived ease of eating a healthful diet was most strongly and consistently predictive of intake.Conclusions Research findings challenge dietetics practitioners to design diet- and health-promotion programs and activities that not only educate the public about the importance of diet to health, but also address barriers to dietary change. 相似文献
9.
肩、肘关节外科新进展 总被引:1,自引:0,他引:1
肩关节(Shoulder)
旋转袖(Rotator Cuff)
基础研究(Basic Science)
Zuckerman讨论了软骨诱导形态发生蛋白-2(cartilagederived morphogenetic protein-2,CDMP-2)的早期工作。在鼠肌腱修复中,4周时CDMP-2治疗组的修复强度高于未治疗组。Dines讨论了关于血小板衍生生长因子(platelet—derived growth factor,PDGF)和胰岛素样生长因子-1(insulin-like growth factor-1,IGF-1)最初的研究观察。 相似文献
10.