全文获取类型
收费全文 | 1951篇 |
免费 | 280篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 93篇 |
儿科学 | 91篇 |
妇产科学 | 17篇 |
基础医学 | 165篇 |
口腔科学 | 29篇 |
临床医学 | 278篇 |
内科学 | 426篇 |
皮肤病学 | 37篇 |
神经病学 | 192篇 |
特种医学 | 112篇 |
外科学 | 315篇 |
综合类 | 83篇 |
现状与发展 | 20篇 |
一般理论 | 3篇 |
预防医学 | 186篇 |
眼科学 | 43篇 |
药学 | 82篇 |
中国医学 | 2篇 |
肿瘤学 | 74篇 |
出版年
2023年 | 44篇 |
2021年 | 33篇 |
2020年 | 27篇 |
2019年 | 29篇 |
2018年 | 71篇 |
2017年 | 71篇 |
2016年 | 50篇 |
2015年 | 61篇 |
2014年 | 67篇 |
2013年 | 88篇 |
2012年 | 85篇 |
2011年 | 80篇 |
2010年 | 75篇 |
2009年 | 82篇 |
2008年 | 92篇 |
2007年 | 62篇 |
2006年 | 80篇 |
2005年 | 54篇 |
2004年 | 61篇 |
2003年 | 52篇 |
2002年 | 43篇 |
2001年 | 52篇 |
2000年 | 41篇 |
1999年 | 50篇 |
1998年 | 46篇 |
1997年 | 49篇 |
1996年 | 53篇 |
1995年 | 38篇 |
1994年 | 35篇 |
1993年 | 28篇 |
1992年 | 30篇 |
1991年 | 39篇 |
1990年 | 36篇 |
1989年 | 33篇 |
1988年 | 52篇 |
1987年 | 44篇 |
1986年 | 43篇 |
1985年 | 29篇 |
1984年 | 18篇 |
1983年 | 12篇 |
1982年 | 20篇 |
1981年 | 8篇 |
1979年 | 17篇 |
1978年 | 24篇 |
1977年 | 18篇 |
1976年 | 12篇 |
1975年 | 8篇 |
1974年 | 15篇 |
1972年 | 8篇 |
1971年 | 10篇 |
排序方式: 共有2248条查询结果,搜索用时 15 毫秒
1.
Sebastian Bonner Thomas Matte Mitchell Rubin Joanne K Fagan Jennifer Ahern David Evans 《The Journal of asthma》2006,43(1):31-35
Although studies have documented underuse of controller medications and overuse of short-acting inhaled ss(2)-agonist among children with persistent asthma in disadvantaged communities, the persistence of oral ss(2)-agonist use in pediatric practice has not been studied since inhaled short-acting ss(2)-agonists became widespread. We describe medications used to treat asthma among children 3 to 5 years of age at 10 Head Start and other subsidized preschool centers in East and Central Harlem, New York City. We interviewed 149 parents/guardians of children who were identified as having probable asthma based on physician's diagnosis, persistent symptoms, hospitalization, and medication use. We classified 86 of the 149 children (58%) as having current persistent asthma. Only 15 of them (17%) were reported to have used controller medications at least 5 days/week in the last 4 weeks-only 2 of whom used inhaled corticosteroids. By contrast, 53 children (62%) used oral ss(2)-agonist in the last 4 weeks, often (72%) in conjunction with nebulized or inhaled short-acting ss(2)-agonist. Use of oral ss(2)-agonist was associated with more severe symptoms. This study documents the continued widespread use of oral ss(2)-agonist for treatment of children in a low-income community with high prevalence of asthma. 相似文献
2.
V Aerra M Kuduvalli AN Moloto AK Srinivasan AD Grayson BM Fabri AY Oo 《Journal of cardiothoracic surgery》2006,1(1):6-5
Background
Atrial fibrillation can occur in up to 40% of patients undergoing coronary surgery. 相似文献3.
The authors screened for alcoholism 145 consecutive patients who presented with sexual dysfunction or disorders. Using the Michigan Alcoholic Screening Test (MAST), 29% of the patients scored in the probable alcoholic range. Probable alcoholics were more likely to present without a partner and claimed higher sex drive than nonalcoholic patients. Probable alcoholic males reported less joy and vigor than probable alcoholic females, while the reverse held for the nonalcoholic groups. Blind to the MAST results, the staff made six alcohol-related diagnoses and referred one patient for alcohol treatment. The authors discussed the importance of training faculty and resident staff in the relationship of alcohol abuse associated with psychosexual dysfunctions. 相似文献
4.
Paul Wexberg MD BM Richard Pacher MD Suzanne Rdler MD Katharina Kiss MD Gilbert Beran MD Michael Grimm MD Gerald Maurer MD Dietmar Glogar MD FESC 《The Journal of heart and lung transplantation》2002,21(12):583-1263
BACKGROUND: Endothelin, a peptide with strong vasoconstrictive and mitogenic properties, has been found to increase after cardiac transplantation. We therefore assessed the association between its precursor peptide, big endothelin-1, and intimal hyperplasia and coronary flow reserve after heart transplantation. METHODS: Thirty-five patients without hemodynamically significant coronary artery disease after heart transplantation were investigated: Average peak flow velocity in the left anterior descending artery (LAD) was assessed by intracoronary Doppler at baseline as well as after injection of adenosine; coronary flow reserve was calculated as a ratio of both and was corrected for patient age and baseline average peak flow velocity. Lumen, intima + media and total vessel area were measured by intracoronary ultrasound. The plasma concentration of big endothelin-1 in venous blood was determined by radioimmunoassay. RESULTS: Patients with elevated big endothelin-1 levels (>2 fmol/ml) tended to have a decreased corrected coronary flow reserve (2.60 +/- 0.9 vs 3.21 +/- 1.0, p = 0.078). They also had a significantly larger intima + media area (5.82 +/- 2.9 vs 2.37 +/- 2.9 mm(2), p = 0.004) and total vessel area (18.36 +/- 5.8 vs 12.81 +/- 4.8 mm(2), p = 0.012) than those with normal plasma concentrations. CONCLUSIONS: Our study suggests an association between elevated big endothelin-1 plasma levels and the development of intimal hyperplasia and reduction of coronary flow reserve after cardiac transplantation. 相似文献
5.
Changing patterns of hip fracture care before and after implementation of the prospective payment system 总被引:6,自引:0,他引:6
We tested the hypothesis that since the implementation of the prospective payment system (PPS), elderly patients hospitalized for hip fractures receive shorter, less care-intensive hospitalizations and are more frequently institutionalized. In blinded fashion, we reviewed the charts of elderly patients with hip fractures admitted to a municipal hospital from 1981 through 1985. Demographic and clinical characteristics of patients treated before implementation of the PPS were similar to patients treated thereafter. After implementation of the PPS, the mean length of hospitalization fell from 16.6 to 10.3 days, and the mean number of physical therapy sessions received decreased from 9.7 to 4.9. Concomitantly, the proportion of patients discharged to a nursing home increased (21% to 48%), as did the proportion receiving nursing home care at six months after discharge (13% to 39%). This increase in long-term nursing home placement suggests that the quality of care for elderly patients with hip fractures may have deteriorated. 相似文献
6.
7.
8.
E A Fagan 《British journal of hospital medicine》1992,47(2):127-131
Recent advances in viral hepatitis reflect the progress of molecular biology. Their clinical applications may provide clues for future prevention. 相似文献
9.
A randomized controlled trial of sedation in the critically ill 总被引:2,自引:0,他引:2
LYNN PARKINSON RSCN JULIE HUGHES RSCN REA GILL MSc IMOGEN BILLINGHAM BM FRCA JANE RATCLIFFE MB ChB FRCP & IMTI CHOONARA MD MRCP 《Paediatric anaesthesia》1997,7(5):405-510
A randomized controlled trial comparing: a) a combination of oral chloral hydrate and promethazine to b) a continuous intravenous midazolam infusion, for maintenance sedation in critically ill children, was carried out. The level of sedation was assessed four hourly using a specifically devized sedation scale. Forty-four children entered the study of whom two were subsequently excluded. The number of satisfactory assessments (desired and actual levels of sedation equal) was significantly greater in the chloral hydrate and promethazine group (Chi-squared P <0.01; confidence intervals of the difference 0.06 to 0.20). The number of assessments at level 5 on the sedation scale (patient restless/distressed) was significantly greater in the midazolam group (Chi-squared P <0.05). The total number of satisfactory assessments in the two groups were only 61 and 48% respectively, suggesting that sedation can be considerably improved. Chloral hydrate and promethazine are more effective than midazolam as maintenance sedation in critically ill children. It is possible to prospectively study the efficacy of sedative drugs in critically ill children. 相似文献
10.