全文获取类型
收费全文 | 1549篇 |
免费 | 85篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 39篇 |
妇产科学 | 33篇 |
基础医学 | 167篇 |
口腔科学 | 17篇 |
临床医学 | 266篇 |
内科学 | 243篇 |
皮肤病学 | 50篇 |
神经病学 | 152篇 |
特种医学 | 32篇 |
外科学 | 155篇 |
综合类 | 59篇 |
一般理论 | 1篇 |
预防医学 | 177篇 |
眼科学 | 38篇 |
药学 | 82篇 |
中国医学 | 4篇 |
肿瘤学 | 106篇 |
出版年
2023年 | 6篇 |
2022年 | 21篇 |
2021年 | 34篇 |
2020年 | 20篇 |
2019年 | 40篇 |
2018年 | 22篇 |
2017年 | 27篇 |
2016年 | 30篇 |
2015年 | 41篇 |
2014年 | 60篇 |
2013年 | 63篇 |
2012年 | 86篇 |
2011年 | 103篇 |
2010年 | 65篇 |
2009年 | 42篇 |
2008年 | 97篇 |
2007年 | 92篇 |
2006年 | 96篇 |
2005年 | 101篇 |
2004年 | 90篇 |
2003年 | 94篇 |
2002年 | 77篇 |
2001年 | 42篇 |
2000年 | 32篇 |
1999年 | 33篇 |
1998年 | 22篇 |
1997年 | 14篇 |
1996年 | 5篇 |
1995年 | 11篇 |
1994年 | 10篇 |
1992年 | 11篇 |
1991年 | 11篇 |
1990年 | 14篇 |
1989年 | 13篇 |
1988年 | 6篇 |
1987年 | 4篇 |
1986年 | 11篇 |
1985年 | 7篇 |
1984年 | 3篇 |
1982年 | 4篇 |
1981年 | 4篇 |
1980年 | 3篇 |
1978年 | 6篇 |
1973年 | 8篇 |
1972年 | 4篇 |
1971年 | 3篇 |
1970年 | 4篇 |
1969年 | 5篇 |
1968年 | 7篇 |
1967年 | 3篇 |
排序方式: 共有1634条查询结果,搜索用时 31 毫秒
1.
Uday Yanamandra Prateek Deo Kamal Kant Sahu Ram Vasudevan Nampoothiri Nalini Gupta Anusree Prabhakaran Deb Prasad Dhibhar Alka Khadwal Gaurav Prakash Man Upadesh Singh Sachdeva Deepesh Lad Neelam Varma Subhash Varma Pankaj Malhotra 《Clinical Lymphoma, Myeloma & Leukemia》2019,19(3):183-189.e1
Background
Multiple myeloma (MM) is a hematologic malignancy of plasma cell origin. MM primarily affects bone marrow, but extramedullary sites can also be involved. Myelomatous pleural effusion (MPE) is an atypical and rare complication of MM. We aimed to systematically study the incidence and clinicopathologic profile of patients with MPE in a real-world setting.Patients and Methods
In this retrospective study, 415 consecutive patients with MM managed at a tertiary care center in North India during a study period of January 1, 2010 to December 31, 2015 were evaluated for MPE. The patients with MPE were analyzed for their clinical profile, diagnosis, treatment, and outcomes.Results
Of these 415 patients, 11 (2.65%) patients had MPE. The median age of the study population was 50 years with male preponderance. The majority of these patients had immunoglobin (Ig)G Kappa disease. All patients had higher than International Staging System stage I disease. MPE was a presenting feature at MM diagnosis in 45.45% (n = 5) of the patients, whereas the rest developed MPE during follow-up. MPE presented predominantly (81.8%) as a unilateral effusion. Concurrent extramedullary involvement at other site was seen in 45.45% (n = 5), with 3 (27%) patients having concurrent myelomatous ascites. Six of these were managed aggressively, whereas 5 patients opted for palliation. The outcomes were dismal (90.9% mortality), with a median survival of 2.47 months.Conclusion
MPE is a rare entity, and positive outcomes of therapy remain low with dismal prognosis. 相似文献2.
3.
Carl J O'Kane Douglas C Tutt Lyndon A Bauer 《Emergency medicine Australasia : EMA》2002,14(3):296-303
Cannabis and driving is an emerging injury‐prevention concern. The incidence of driving while affected by cannabis is rising in parallel with increased cannabis use in the community. Younger drivers are at particular risk. Improvements in research methodology, technology and laboratory testing methods have occurred in the last 10 years. These cast doubt on earlier results and conclusions. Studies now show that cannabis has a significant impairing effect on driving when used alone and that this effect is exaggerated when combined with alcohol. Of particular concern is the presence of cannabis as the sole psychoactive drug in an increasing number of road fatalities and the lack of any structural response to this problem. A review of testing methods, laboratory and real driving studies, and recent epidemiological studies is presented. Suggestions for methods of further data collection and future public policy are made. 相似文献
4.
M M O'Kane P A King H D Edmondson 《International journal of oral and maxillofacial surgery》1986,15(4):422-424
Button wiring has been used as an alternative to eyelet wiring in the Department of Oral and Dental Surgery of Birmingham General Hospital since 1977. This clinical update reviews 65 patients with mandibular fractures in which button wires were utilised in their treatment. 相似文献
5.
6.
7.
Pelvic ultrasound is a widely used diagnostic tool and accessto this investigation is not universally available to all generalpractitioners (GPs). The aim of this study was to assess ifGPs working in the United Arab Emirates (UAE) were using pelvicultrasound appropriately by determining the rates of diagnosticyield and referral after the investigation. It was then ascertainedif these results were affected by the post-graduate trainingor gender of the doctor. The subjects were adult females whohad had a pelvic ultrasound ordered by a GP over a 2-month period.A chart review determined the presenting complaint, the completenessof the request form, the result of the ultrasound and subsequentmanagement of the patient. Diagnostic yields and referral rateswere similar to those found in other studies and were unaffectedby the post graduate training or gender of the doctor or theamount of information contained in the request form. This studysupports the premise that GPs can use pelvic ultrasound appropriatelyand should be allowed free access to this investigation. 相似文献
8.
Burn injuries can be caused by thermal, electrical, chemical, or mechanical trauma or radiation and are relatively rare, as they represent only about 1% of all emergencies. They are caused by accidents at home, during recreational activities, or in the occupational environment. Minor burn traumas are much more common than severe burn injuries with their systemic and potentially life-threatening effects. Altogether, these circumstances may result in a lack of routine for treating such injuries properly by physicians and their colleagues in the emergency room or intensive care unit. A clearly outlined concept for preclinical and clinical treatment can be the keystone of successful further clinical progress. The following article summarizes the current guidelines for first medical aid at the injury scene, burn stabilization and assessment in the emergency room, and the interdisciplinary approach for further clinical care. The treatment of dermatologic emergencies (acute epidermolytic syndromes) or caustic injuries by chemical agents is similar to the treatment of burn victims in many aspects but must be adapted in selected cases. 相似文献
9.
10.