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Giacobbe Chiara Raimo Simona Cropano Maria Santangelo Gabriella 《Brain imaging and behavior》2022,16(5):2353-2374
Brain Imaging and Behavior - The neural correlates of action language processing are still debated within embodied cognition research and little is known about the flexible involvement of... 相似文献
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Maggi Gianpaolo Baldassarre Ivana Barbaro Andrea Cavallo Nicola Davide Cropano Maria Nappo Raffaele Santangelo Gabriella 《Neurological sciences》2022,43(3):1521-1532
Neurological Sciences - Individuals experienced psychological symptoms in response to quarantine for the COVID-19 pandemic. Therefore, we aimed to investigate the possible effect of age... 相似文献
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D. Dante Yeh Yuchiao Chang Maryam Bita Tabrizi Liyang Yu Catrina Cropano Peter Fagenholz David R. King Haytham M.A. Kaafarani Marc de Moya George Velmahos 《The American journal of emergency medicine》2019,37(1):61-66
Objective
We sought to develop a practical Bedside Score for the diagnosis of cholecystitis and test its accuracy against the Tokyo Guidelines (TG13).Methods
We conducted a retrospective study of 438 patients undergoing urban, academic Emergency Department (ED) evaluation of RUQ pain. Symptoms, physical signs, ultrasound signs, and labs were scoring system candidates. A random split-sample approach was used to develop and validate a new clinical score. Multivariable regression analysis using development data was conducted to identify predictors of cholecystitis. Cutoff values were chosen to ensure positive/negative predictive values (PPV, NPV) of at least 0.95. The score was externally validated in 80 patients at a different hospital undergoing RUQ pain evaluation.Results
230 patients (53%) had cholecystitis. Five variables predicted cholecystitis and were included in the scores: gallstones, gallbladder thickening, clinical or ultrasonographic Murphy's sign, RUQ tenderness, and post-prandial symptoms. A clinical prediction score was developed. When dichotomized at 4, overall accuracy for acute cholecystitis was 90% for the development cohort, 82% and 86% for the internal and external validation cohorts; TG13 accuracy was 62%–79%.Conclusions
A clinical prediction score for cholecystitis demonstrates accuracy equivalent to TG13. Use of this score may streamline work-up by decreasing the need for comprehensive ultrasound evaluation and CRP measurement and may shorten ED length of stay. 相似文献4.
D. Dante Yeh MD Eva Fuentes MD Sadeq A. Quraishi MD MHA MMScH Catrina Cropano MSc Haytham Kaafarani MD MPH Jarone Lee MD MPH David R. King MD Marc DeMoya MD Peter Fagenholz MD Kathryn Butler MD Yuchiao Chang PhD George Velmahos MD PhD 《JPEN. Journal of parenteral and enteral nutrition》2016,40(1):37-44
Background: Macronutrient deficit in the surgical intensive care unit (ICU) is associated with worse in‐hospital outcomes. We hypothesized that increased caloric and protein deficit is also associated with a lower likelihood of discharge to home vs transfer to a rehabilitation or skilled nursing facility. Materials and Methods: Adult surgical ICU patients receiving >72 hours of enteral nutrition (EN) between March 2012 and May 2014 were included. Patients with absolute contraindications to EN, <72‐hour ICU stay, moribund state, EN prior to surgical ICU admission, or previous ICU admission within the same hospital stay were excluded. Subjects were dichotomized by cumulative caloric (<6000 vs ≥6000 kcal) and protein deficit (<300 vs ≥300 g). Baseline characteristics and outcomes were compared using Wilcoxon rank and χ2 tests. To test the association of macronutrient deficit with discharge destination (home vs other), we performed a logistic regression analysis, controlling for plausible confounders. Results: In total, 213 individuals were included. Nineteen percent in the low‐caloric deficit group were discharged home compared with 6% in the high‐caloric deficit group (P = .02). Age, body mass index (BMI), Acute Physiology and Chronic Health Evaluation II (APACHE II), and initiation of EN were not significantly different between groups. On logistic regression, adjusting for BMI and APACHE II score, the high‐caloric and protein‐deficit groups were less likely to be discharged home (odds ratio [OR], 0.28; 95% confidence interval [CI], 0.08–0.96; P = .04 and OR, 0.29; 95% CI, 0.0–0.89, P = .03, respectively). Conclusions: In surgical ICU patients, inadequate macronutrient delivery is associated with lower rates of discharge to home. Improved nutrition delivery may lead to better clinical outcomes after critical illness. 相似文献
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