全文获取类型
收费全文 | 834篇 |
免费 | 88篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 22篇 |
儿科学 | 16篇 |
妇产科学 | 7篇 |
基础医学 | 103篇 |
口腔科学 | 32篇 |
临床医学 | 79篇 |
内科学 | 161篇 |
皮肤病学 | 31篇 |
神经病学 | 144篇 |
特种医学 | 8篇 |
外科学 | 107篇 |
综合类 | 25篇 |
一般理论 | 3篇 |
预防医学 | 76篇 |
眼科学 | 11篇 |
药学 | 46篇 |
中国医学 | 1篇 |
肿瘤学 | 51篇 |
出版年
2023年 | 21篇 |
2022年 | 34篇 |
2021年 | 76篇 |
2020年 | 36篇 |
2019年 | 56篇 |
2018年 | 37篇 |
2017年 | 16篇 |
2016年 | 13篇 |
2015年 | 22篇 |
2014年 | 24篇 |
2013年 | 29篇 |
2012年 | 24篇 |
2011年 | 32篇 |
2010年 | 20篇 |
2009年 | 15篇 |
2008年 | 21篇 |
2007年 | 27篇 |
2006年 | 27篇 |
2005年 | 18篇 |
2004年 | 27篇 |
2003年 | 24篇 |
2002年 | 20篇 |
2001年 | 17篇 |
2000年 | 19篇 |
1999年 | 9篇 |
1998年 | 4篇 |
1997年 | 8篇 |
1995年 | 8篇 |
1994年 | 14篇 |
1993年 | 4篇 |
1992年 | 17篇 |
1991年 | 13篇 |
1990年 | 24篇 |
1989年 | 19篇 |
1988年 | 21篇 |
1987年 | 14篇 |
1986年 | 17篇 |
1985年 | 9篇 |
1984年 | 13篇 |
1983年 | 11篇 |
1981年 | 3篇 |
1980年 | 3篇 |
1979年 | 6篇 |
1974年 | 3篇 |
1973年 | 3篇 |
1972年 | 3篇 |
1970年 | 5篇 |
1968年 | 4篇 |
1964年 | 4篇 |
1961年 | 3篇 |
排序方式: 共有923条查询结果,搜索用时 12 毫秒
1.
2.
Parker N. Hyde Teryn N. Sapper Richard A. LaFountain Madison L. Kackley Alex Buga Brandon Fell Christopher D. Crabtree Stephen D. Phinney Vincent J. Miller Sarah M. King Ronald M. Krauss William J. Kraemer Jeff S. Volek 《Nutrients》2021,13(6)
Background. Foods rich in saturated fatty acids (SFAs) have been discouraged by virtue of their cholesterol-raising potential, but this effect is modulated by the food source and background level of carbohydrate. Objective. We aimed to compare the consumption of palm stearin (PS) versus butter on circulating cholesterol responses in the setting of both a low-carbohydrate/high-fat (LC/HF) and high-carbohydrate/low-fat (HC/LF) diet in healthy subjects. We also explored effects on plasma lipoprotein particle distribution and fatty acid composition. Methods. We performed a randomized, controlled-feeding, cross-over study that compared a PS- versus a Butter-based diet in a group of normocholesterolemic, non-obese adults. A controlled canola oil-based ‘Run-In’ diet preceded the experimental PS and Butter diets. All diets were eucaloric, provided for 3-weeks, and had the same macronutrient distribution but varied in primary fat source (40% of the total fat). The same Run-In and cross-over experiments were done in two separate groups who self-selected to either a LC/HF (n = 12) or a HC/LF (n = 12) diet track. The primary outcomes were low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein (HDL)-C, triglycerides, and LDL particle distribution. Results. Compared to PS, Butter resulted in higher LDL-C in both the LC/HF (13.4%, p = 0.003) and HC/LF (10.8%, p = 0.002) groups, which was primarily attributed to large LDL I and LDL IIa particles. There were no differences between PS and Butter in HDL-C, triglycerides, or small LDL particles. Oxidized LDL was lower after PS than Butter in LC/HF (p = 0.011), but not the HC/LF group. Conclusions. These results demonstrate that Butter raises LDL-C relative to PS in healthy normocholesterolemic adults regardless of background variations in carbohydrate and fat, an effect primarily attributed to larger cholesterol-rich LDL particles. 相似文献
3.
Anderson Madison D. Merkin Sharon Stein Everson-Rose Susan A. Widome Rachel Seeman Teresa Magnani Jared W. Rodriguez Carlos J. Lutsey Pamela L. 《Journal of immigrant and minority health / Center for Minority Public Health》2021,23(4):668-668
Journal of Immigrant and Minority Health - The original version of this article unfortunately contained a typo in co-author name. 相似文献
4.
Anghela Z. Paredes J. Madison Hyer Diamantis I. Tsilimigras Mary Dillhoff Jordan M. Cloyd Aslam Ejaz Allan Tsung Courtney Collins Timothy M. Pawlik 《American journal of surgery》2021,221(3):492-496
IntroductionWe sought to determine the impact of payer-mix on post-operative outcomes among Medicare beneficiaries following hepatopancreatic surgery.MethodsMedicare beneficiaries who underwent hepatopancreatic surgery were identified. Hospital quality markers were obtained from the Hospital General Information dataset. Hospitals were dichotomized (low/average vs. high) based on Medicare patient days versus all patient days irrespective of payer type.ResultsHigh Medicare patient-mix hospitals were more likely to be ranked higher than the national average relative to safety of care (29.4% vs. 38.1%) and timeliness of care (15.4% vs. 26.3%) versus low burden Medicare hospitals (both p < 0.001). However, Medicare beneficiaries who had hepatopancreatic surgery at a high Medicare patient-mix hospital were at higher risk of a complication (OR = 1.13, 95%CI 1.04–1.22), and death within 30-days (OR = 1.37, 95%CI 1.23–1.53) following surgery.ConclusionWhile hospitals caring for higher numbers of Medicare beneficiaries generally performed better on CMS quality indicators, these rankings did not equate to improved post-operative outcomes. 相似文献
5.
Tsilimigras Diamantis I. Dalmacy Djhenne Hyer J. Madison Diaz Adrian Abbas Alizeh Pawlik Timothy M. 《Annals of surgical oncology》2021,28(13):8162-8171
Annals of Surgical Oncology - Racial/ethnic disparities in cancer outcomes may relate to variations in receipt of National Comprehensive Cancer Network (NCCN) guideline compliant... 相似文献
6.
Annals of Surgical Oncology - 相似文献
7.
Azap Rosevine A. Diaz Adrian Hyer J. Madison Tsilimigras Diamantis I. Mirdad Rayyan S. Ejaz Aslam Pawlik Timothy M. 《Annals of surgical oncology》2021,28(3):412-413
Annals of Surgical Oncology - 相似文献
8.
Jennifer F. Madison Philip H. Cooper Walter H. C. Burgdorf 《Journal of cutaneous pathology》1990,17(4):220-224
This report describes two patients with mucinous syringometaplasia whose findings expand the microscopic and clinical spectrum of the entity. The first patient had an eroded nodule that exhibited multiple epidermal invaginations that penetrated deeply into the dermis. In addition to mucinous metaplasia, there was also exuberant papillary epithelial hyperplasia. Expanded eccrine ducts with similar changes appeared as lobules isolated in the dermis but were shown to connect with the invaginations. In the second patient, a clinical "cyst" drained serous fluid. Multiple papillary-cystic epithelial lobules similar to those seen in the first case were located in the dermis. A few approached the epidermis, but epidermal connections were not identified. The epithelium in these lesions was identical to that previously described in mucinous syringometaplasia. The tumors differed from prior cases by virtue of the number of eccrine apparatus involved, the extent and depth of involvement, and the presence of prominent papillary epithelial hyperplasia. 相似文献
9.
10.
Host brain receptivity to fetal hippocampal grafts was investigated following transplantation into unilateral kainic acid (KA) lesions of adult rat hippocampus. E18-E19 hippocampal cell suspensions were labeled with rhodamine dextran amine and transplanted bilaterally into hosts at various times following the KA-lesion. After one to three and one half months survival the grafts (contained within host hippocampal slices) were analyzed using intracellular electrophysiological techniques. A nonparametric graft index was developed which assessed the overall size and distribution of the graft. Using this grading system graft development was noted to be significantly enhanced for grafts placed into hosts with KA lesions at either 2-4 days or 11-12 days following the lesion, compared to grafts placed at either 6-7 days or 27-33 days after the lesion. Also, grafts implanted at delays of either 14-16 or 28-33 days appeared to have fewer surviving cells but were more dispersed within the host brain than grafts at shorter post-lesion implant times. Synaptic responses to host stimulation were noted in most grafts. Intracellular staining of transplanted neurons showed considerable development of cell processes but atypical pyramidal cell morphology and ectopic location; numerous axons traveled into the host tissue. The time course of lesion-induced host receptivity appeared to significantly influence graft development and maturation. In this study graft survival was partially independent from cell migration. This differential effect may be due to various aspects of host brain receptivity, which in turn is influenced by the delay between the host brain lesion and grafting. 相似文献