全文获取类型
收费全文 | 19902篇 |
免费 | 1207篇 |
国内免费 | 67篇 |
专业分类
耳鼻咽喉 | 201篇 |
儿科学 | 575篇 |
妇产科学 | 489篇 |
基础医学 | 2890篇 |
口腔科学 | 542篇 |
临床医学 | 1821篇 |
内科学 | 4762篇 |
皮肤病学 | 325篇 |
神经病学 | 1847篇 |
特种医学 | 504篇 |
外国民族医学 | 1篇 |
外科学 | 2394篇 |
综合类 | 166篇 |
一般理论 | 8篇 |
预防医学 | 1639篇 |
眼科学 | 326篇 |
药学 | 1131篇 |
中国医学 | 45篇 |
肿瘤学 | 1510篇 |
出版年
2023年 | 180篇 |
2022年 | 395篇 |
2021年 | 785篇 |
2020年 | 428篇 |
2019年 | 615篇 |
2018年 | 683篇 |
2017年 | 516篇 |
2016年 | 523篇 |
2015年 | 571篇 |
2014年 | 756篇 |
2013年 | 1041篇 |
2012年 | 1657篇 |
2011年 | 1542篇 |
2010年 | 939篇 |
2009年 | 731篇 |
2008年 | 1273篇 |
2007年 | 1298篇 |
2006年 | 1123篇 |
2005年 | 1196篇 |
2004年 | 999篇 |
2003年 | 854篇 |
2002年 | 830篇 |
2001年 | 189篇 |
2000年 | 137篇 |
1999年 | 172篇 |
1998年 | 131篇 |
1997年 | 116篇 |
1996年 | 112篇 |
1995年 | 112篇 |
1994年 | 88篇 |
1993年 | 76篇 |
1992年 | 85篇 |
1991年 | 65篇 |
1990年 | 74篇 |
1989年 | 48篇 |
1988年 | 55篇 |
1987年 | 44篇 |
1986年 | 60篇 |
1985年 | 51篇 |
1984年 | 44篇 |
1983年 | 61篇 |
1982年 | 44篇 |
1981年 | 34篇 |
1980年 | 39篇 |
1979年 | 30篇 |
1977年 | 26篇 |
1976年 | 23篇 |
1975年 | 22篇 |
1974年 | 30篇 |
1972年 | 22篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Renaud Snanoudj Nassim Kamar Elisabeth Cassuto Sophie Caillard Marie Metzger Pierre Merville Antoine Thierry Isabelle Jollet Philippe Grimbert Dany Anglicheau Marc Hazzan Gabriel Choukroun Bruno Hurault De Ligny Bénedicte Janbon Vincent Vuiblet Anne Devys Yann Le Meur Michel Delahousse Jean-Luc Taupin 《Kidney international》2019,95(6):1471-1485
2.
3.
Attila Szalmas Peter Bodrogi Cecilia Sik-Lanyi 《Ophthalmic & physiological optics》2006,26(3):281-287
The objective of this study is to test the luminous efficiency functions V(lambda), V'(lambda), V(10)(lambda) and their linear combinations on the basis of a data set gained from a simulated mesopic night-time driving experiment. Another aim is to provide 'real-world' data for the 'X framework' or 'linear combination model', and to find out its limits in a practical situation. Human performance was measured by the reaction time method. Results show that the single parameter of the linear combination of photopic and scotopic luminous efficiency functions can be determined analytically with little variation for a given mesopic background luminance level and a given visual target colour, but the computation leads to considerable deviations comparing all three target colours (red, green and blue) used in the experiment. The conclusion for the given experimental conditions is that the single parameter of the linear combination model has an increasing deviation for lower background luminance levels. 相似文献
4.
5.
Quantitatively distinct requirements for signaling-competent cell spreading on engineered versus natural adhesion ligands. 总被引:1,自引:0,他引:1
Gabriel P Richman David A Tirrell Anand R Asthagiri 《Journal of controlled release》2005,101(1-3):3-12
To design synthetic microenvironments that elicit desired cell behaviors, we must better understand the molecular mechanisms by which cells interact with candidate biomaterials. Using cell lines with distinct alpha5beta1 integrin expression profiles, we demonstrate that this integrin mediates cell spreading on substrata coated with genetically engineered artificial extracellular matrix (aECM) proteins containing the RGD sequence (RGD-containing aECM protein [aRGD]) but lacking the PHSRN synergy site. Furthermore, aRGD-mediated adhesion stimulates an intracellular focal adhesion kinase (FAK) signal that is indicative of integrin tethering. Although both aRGD and the natural ECM protein fibronectin (FN) support alpha5beta1 integrin-mediated cell spreading, quantitative single-cell analysis revealed that aRGD-mediated spreading requires ten-fold greater threshold amount of integrin expression than FN-mediated spreading. Our analysis demonstrates that aRGD-based substrata mediate both biophysical (cell spreading) and biochemical (FAK signaling) events via the alpha5beta1 integrin, albeit with efficacy quantitatively distinct from that of natural ECM proteins that possess the full spectrum of adhesion and synergy domains. 相似文献
6.
Roberto H. Caraballo Laura Gañez Cecilia De los Santos Alberto Espeche Ricardo Cersósimo Natalio Fejerman 《Seizure》2009,18(10):686-689
PurposeTo analyze the electroclinical features, aetiology and outcome in patients with normal neurological examination and psychomotor development who presented seizures during a mild gastroenteritis (MG).Patients and methodsEvaluation of the clinical charts of 22 patients who were assessed in the Neurology Department, Hospital Nacional de Pediatría Prof. Dr. JP Garrahan between 1999 and 2007.ResultsTwelve patients were boys and 10 were girls, the age of onset ranged from 5 to 26 months, and the median age was 10 months. Rotavirus antigen test in stool was positive in 9 of 18 studied patients. The seizures were brief, focal with secondary generalization in 15 patients (68.5%), apparently generalized in 5 (22.5%) and focal in two (9%). Seven of the patients (35%) had more than one seizure in 24 h. The interictal EEG was normal in all patients. Neuroradiological studies were performed in 19 patients with a normal result. No patient was put on long-term treatment with antiepileptic drugs. Four patients had subsequent mild gastroenteritis and two of them presented convulsions during the disease. After between 12 and 67 months of follow-up, all patients had normal psychomotor development and neurological examination.ConclusionsIn this study we confirmed the association of benign infantile seizures (BIS) and MG with or without rotavirus. The identification of this entity allows avoiding unnecessary complementary studies and treatment with antiepileptic drugs. 相似文献
7.
Mao-Sheng Ran Meng-Ze Xiang Jie Li Jian Huang Eric Yu-Hai Chen Cecilia Lai-Wan Chan Yeates Conwell 《Archives of Suicide Research》2007,11(1):119-127
The aim of this study was to compare the demographic and clinical characteristics of individuals with affective disorders who had attempted suicide at some time in their lives and those who had not made a suicide attempt. In a Chinese rural community, individuals with suicide attempt (N = 30) and those without suicide attempt (N = 166) were assessed with Present State Examination (PSE). Attempters had a significantly higher level of family economic status, higher rate of lifetime depressed mood and hopelessness, and delusions than nonattempters. The logistic regression models also indicated that depressed mood and hopelessness were the most important predictors of suicide attempts. No significant difference in treatment condition was found between attempters and non-attempters. Early identification and interventions focusing on reducing depressed mood, hopelessness, and controlling psychotic symptoms may be helpful in reducing the risk of suicide attempts among individuals with affective disorders residing in the community. 相似文献
8.
Andrea Berger Michelle Sadeh Gabriel Tzur I Avinoam Shuper Liora Kornreich Dov Inbar Ian J Cohen Shalom Michowiz Isaac Yaniv Shlomi Constantini Eli Vakil 《Journal of the International Neuropsychological Society》2005,11(4):482-487
Cerebellar involvement in motor and non-motor sequence learning was examined with serial reaction time tasks (SRT). Our sample consisted of 8 children and adolescents who had undergone surgical removal of a benign posterior fossa tumor (PFT) during childhood. None of them had undergone chemotherapy or cranial radiation therapy (CRT). Ages ranged from 1-11 years at surgery and 9-17 years at testing. The children were tested not earlier than 2.5 years after surgery (M = 5.9 years), enabling brain plasticity and recovery of functions. Their performance was compared with a matched control sample. The PFT group was not impaired in the implicit learning of sequences, as reflected in their performance in blocks with a repeated sequence, both before and after a random block. However, in the perceptual task, their performance deteriorated more than that of the control group when a random block was introduced, suggesting that it was more difficult for the patients to respond flexibly or change their response set when encountering changing task demands. These results are in line with another study by our group on task switching with the same patients. 相似文献
9.
10.