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1.
1-乙基-6-氟-1,4-二氢-4-氧代-7-(4-芳酰硫代氨甲酰基-1-哌嗪基)-3-喹啉羧酸的合成及抗菌作用 总被引:4,自引:1,他引:3
Thirteen new 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-aroyl-thiocarbamoyl- 1 piperazinyl)-3-quinoline carboxylic acids were prepared, Their structures were characterized by elemental analysis, IR, HNMR and MS spectra.Preliminary pharmacological tests indicated that some of compounds Ia~m possess strong inhibiting activity against Escherichia coli, Bacillus subtilis and Proteus at concentration of 100 μg/ml. 相似文献
2.
Lucy Yardley David Papo Adolfo Bronstein Michael Gresty Mark Gardner Nilli Lavie Linda Luxon 《Neuropsychologia》2002,40(4):373-383
The aim of this series of experiments was to determine whether attention is normally required for continuously processing vestibular information concerning orientation, or is required only when orientation is disrupted (eg by vestibular dysfunction or by conflicting visual and vestibular orientation cues). In the first two studies, healthy subjects were passively oscillated, and indicated when they perceived they were passing through their starting position. There was only weak evidence for interference between performance on this 'continuous orientation monitoring task' and on concurrent mental tasks. However, a third study showed that when patients with vestibular imbalance carried out the continuous orientation monitoring task their performance on a concurrent mental arithmetic task was substantially impaired. This dual task interference was correlated with inaccuracy in judging orientation on the continuous orientation monitoring task, which in turn correlated with severity of recent vestibular symptomatology (assessed by questionnaire). In a fourth experiment, disorientation was induced in healthy subjects by rotating the visual field about the line of sight. Bidirectional interference was observed between monitoring orientation (assessed by accuracy in setting a rod to the perceived vertical) and performance of an arithmetic task. Dual task interference was correlated with baseline levels of disorientation induced by the visual field, as indicated by inaccuracy in judging the visual vertical. These findings suggest that monitoring orientation makes significant demands upon cortical processing resources when disorientation is induced, whether the disorientation results from deficient sensory functioning or from ambiguous perceptual information. 相似文献
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S L Bronstein 《Oral surgery, oral medicine, and oral pathology》1987,64(2):135-145
The surgical treatment of intermediate- to late-stage temporomandibular joint disease often involves disk removal. In many instances, disks have not been replaced; long-term postsurgical findings of crepitation and osseous remodeling have been noted although subjective signs and symptoms have been few. Attempts to decrease the noises and bony changes, to enhance biologic resurfacing, and to prevent adhesions, recurrent pain, and dysfunction have prompted many surgeons to use various alloplastic materials to replace the disk, either in a planned permanent (retained) or a planned temporary (retrievable) manner. However, a certain degree of morbidity remains. This article reports clinical responses and radiographic findings in a series of patients who received retained alloplastic temporomandibular joint disk implants. 相似文献
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Complications of needle localization of foreign bodies and nonpalpable breast lesions 总被引:1,自引:0,他引:1
Needle-wire localization of foreign bodies and nonpalpable breast lesions is commonly used to allow for more accurate excision or biopsy. We present three examples of complications of the localization procedure: (1) wire migration into the chest wall with retained fragment, (2) transection of a wire during biopsy with retained hook fragment, and (3) wire migration within the thigh soft tissues with breakage at the hooked end. Recommendations to minimize the incidence of these complications and their sequelae include (1) bending the hookwire 90 degree at the skin surface following localization, (2) transferring the patient between the radiology suite and the operating room via a stretcher, with minimal movement of the body part localized, and (3) accounting for the entire length of wire by the surgeon, pathologist, and radiologist following the procedure to exclude retained fragments. 相似文献
8.
大狼毒三萜类化学成分的研究 总被引:3,自引:0,他引:3
自大戟科(Euphorbiaceae)植物大狼毒(Euphorbia nematocypha Hand—Mazz)根的乙醇提取物的苯溶解部分,经20%AgNO3硅胶层析,分离得到七个三萜类成分。根据光谱(IR,EIMS,1H—NMR和13C—NMR)和化学方法,确定其中一个化合物为新化合物,命名为大狼毒醇(nematocyphol,Ⅳa),其它化合物为已知物:印度荆芥醇乙酸酯(nepehinol acetate Ⅰ),日尔曼醇乙酸酯(germanicol acetate Ⅱ),大戟醇(euphol,Ⅲ),蒲公英醇(taraxasterol,Ⅴa),24-亚甲基环阿尔廷醇(24-methylenecycloartanol,Ⅴa)和印度荆芥醇(nepehinol,Ⅶa)。这些化合物均为首次从大狼毒中得到。 相似文献
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Eye movements induced by lateral acceleration steps
Effect of visual context and acceleration levels
C. C. Gianna Michael A. Gresty Adolfo M. Bronstein 《Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale》1997,114(1):124-129
Eye movement responses were obtained from six normal subjects exposed to randomly ordered rightwards/leftwards linear acceleration
steps of 0.05 g, 0.1 g or 0.24 g amplitude and 650 ms duration along the inter-aural axis. With the instruction to gaze passively into the darkness, compensatory nystagmus was evoked with slow-phase velocity sensitivity of 49° s−1
g
−1. When subjects viewed earth-fixed targets at 30 cm, 60 cm or 280 cm, eye movements at 130 ms from motion onset were proportional to acceleration and inversely proportional
to target distance, before the onset of visually guided eye movements. Our results show that a modulation with viewing distances
of the earliest human otolith-ocular reflexes occurs in the presence of pure linear acceleration. However, full compensation
was not attained for the nearer targets and higher accelerations.
Received: 31 January 1996 / Accepted: 30 September 1996 相似文献