排序方式: 共有61条查询结果,搜索用时 15 毫秒
1.
Brilhante OM Tambellini AM 《International journal of environmental health research》2002,12(2):169-174
This paper investigates the existence of a possible relationship between suspended particulate matters levels and cases of respiratory diseases from a random and systematic sample of medical and air pollution records in the metropolitan area of Rio de Janeiro. Records of emergency cases of the year 1991 (months of January, June and July) were collected at Miguel Couto Hospitals and suspended particulate matter (1980-1995) at FEEMA (Rio de Janeiro Environmental Agency). The results revealed that the diseases of the respiratory system of those patients who seek the hospital's emergency care are more frequent during the wintertime. Their number increases markedly during winter months of June and July when compared with the summer's (January) number of cases. The analysis of the historical series (1980-1995) of atmospheric pollution measured at Bonsucesso monitoring station showed that the monthly figures (measured by the number of times that the value exceed the national standard, maximum daily concentration of 240 micro g (-3), are higher in wintertime (June, July and August). During this same period the level of pollution by atmospheric particulate matter in Rio de Janeiro metropolitan area measured by the annual geometric averages showed results well above the national standard (80 micro g(-3). This unfavorable situation, together with the fast growing number of new cars circulating in the city and the absence of a clear air pollution control and management plan, may contribute to an increase of the incidence and seriousness of respiratory diseases during subsequent winter months. 相似文献
2.
O. Magno Brilhante R. Maria Oliveira 《International journal of environmental health research》1996,6(1):17-25
A factory where hexachlorocyclohexane was manufactured, was closed down in 1955. Part of its production, that is, many tons of technical grade HCH, were left behind on a site called ‘Cidade dos Meninos’ located near the city of Rio de Janeiro, in Brazil. This pesticide ended up swept by the rain, wind and taken by local people, more than 1000 individuals, including 400 children and adolescents who live in the LBA (Brazilian Assistance Corps)‐owned orphanage called ‘Cristo Redentor Asylum’. The product was used to kill cockroach, lice and to fight the mosquitos responsible for malaria disease. The highest concentrations, thousands of ppb of HCH isomers, were found in soil samples collected less than 100 m away from the former factory and in samples of the grass on which the local cattle feed. Vertical soil profiles were also analyzed. Blood specimens from 31 adults and approximately 25% of the children living in the asylum located 1.5 km from the ruin of the former factory also showed contamination by the α, γ, and particularly β, isomers. 相似文献
3.
Freitas MB Brilhante OM Almeida LM 《Cadernos de saúde pública / Ministério da Saúde, Funda??o Oswaldo Cruz, Escola Nacional de Saúde Pública》2001,17(3):651-660
In developing countries, due to poor sanitation conditions and poor quality of drinking water, typical water-borne diseases and more recently diseases caused by drinking water with high concentrations of nitrates and certain metals like aluminum have increased the concern over the health effects of these compounds. Several articles have shown associations between nitrates and methemoglobinemia in children, and aluminum and Alzheimer disease in adults. This study identified water quality with several parameters in non-conformity with Brazilian drinking water standards (Ruling 36/90): more than 50% of all samples from both regions contained fecal coliforms; some 31% of water samples from wells in Duque de Caxias had excessive nitrate concentrations; 100% of all groundwater samples from both regions showed aluminum concentrations not conforming to the norm, with the same result for 100% of samples from the drinking water distribution system in S?o Gon?alo and 75% of same in Duque de Caxias. This lack of conformity poses several health risks for the local population. 相似文献
4.
Brilhante RS Cordeiro RA Rocha MF Monteiro AJ Meireles TE Sidrim JJ 《International journal of dermatology》2004,43(8):575-579
BACKGROUND: Over a 3-year period (March 1999 to March 2002), 944 patients with scalp lesions attended a dermatology reference center in the city of Fortaleza, Ceará, Brazil. Clinical specimens were examined at the Specialized Medical Mycology Center, Federal University of Ceará, Fortaleza-CE, Brazil, to detect patients with tinea capitis. METHODS: Specimens were obtained from pus, scales, and hairs from suspected lesions of tinea capitis. Mycologic analyses were conducted by direct microscopy and by fungal culture on Sabouraud dextrose agar, with or without chloramphenicol and Mycosel agar. The culture tubes were incubated at 28 degrees C and examined daily for 1 month. RESULTS: Fungi were seen in 438 (46.4%) of the 944 clinical specimens. The percentage of positive direct microscopic examinations of the clinical specimens was 83.7%. Of those patients with tinea capitis, 157 (35.8%) were males and 281 (64.2%; P < 0.001) were females. The distribution of dermatophyte species in males, from 136 positive cultures, was Trichophyton tonsurans (54.41%), Microsporum canis (38.97%), T. rubrum (4.41%), T. mentagrophytes var. mentagrophytes (1.47%), and M. gypseum (0.74%). On the other hand, only three species, from 251 positive cultures, were present in females: T. tonsurans (80.08%), M. canis (17.53%), and T. rubrum (2.39%). There was a high proportion of positive results in children under 10 years of age (n = 309). No significant difference was detected in the seasonal distribution of tinea capitis. CONCLUSIONS: Our data show that T. tonsurans is the main etiologic agent of tinea capitis, and is more likely to be found in females and in the prepubertal population. 相似文献
5.
Cordeiro Rde A e Silva KR Brilhante RS Moura FB Duarte NF Marques FJ Cordeiro Rde A Filho RE de Araújo RW Bandeira Tde J Rocha MF Sidrim JJ 《Emerging infectious diseases》2012,18(4):668-670
To analyze the eco-epidemiologic aspects of Histoplasma capsulatum in Brazil, we tested 83 bats for this fungus. Although H. capsulatum was not isolated, Coccidioides posadasii was recovered from Carollia perspicillata bat lungs. Immunologic studies detected coccidioidal antibodies and antigens in Glossophaga soricina and Desmodus rotundus bats. 相似文献
6.
Cordeiro Rde A Marques FJ Brilhante RS Rocha de Castro E Silva K Mourão CI Caetano EP Fechine MA Ribeiro JF Castelo-Branco Dde S de Lima RA Mesquita JR Monteiro AJ Rocha FA Rocha MF Sidrim JJ 《Antimicrobial agents and chemotherapy》2011,55(9):4482-4484
This study evaluated in vitro interactions of antituberculosis drugs and triazoles against Histoplasma capsulatum. Nine drug combinations, each including an antituberculosis drug (isoniazid, pyrazinamide, or ethambutol) plus a triazole (itraconazole, fluconazole, or voriconazole), were tested against both growth forms of H. capsulatum. Stronger synergistic interactions were seen in isoniazid or pyrazinamide plus triazoles for the mold form and ethambutol plus voriconazole for the yeast-like form. Further studies should evaluate these combinations in vivo. 相似文献
7.
8.
Cross‐resistance to fluconazole induced by exposure to the agricultural azole tetraconazole: an environmental resistance school?
下载免费PDF全文
![点击此处可从《Mycoses》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Marcos Fábio Gadelha Rocha L. P. Alencar M. A. N. Paiva Luciana Magalhães Melo Silviane Praciano Bandeira Y. B. Ponte Jamille Alencar Sales G. M. M. Guedes D. S. C. M. Castelo‐Branco T. J .P. G. Bandeira R. A. Cordeiro W. A. Pereira‐Neto G. S. Brandine José Luciano Bezerra Moreira José Júlio Costa Sidrim Raimunda Sâmia Nogueira Brilhante 《Mycoses》2016,59(5):281-290
This study aimed to investigate the influence of tetraconazole and malathion, both used in agricultural activities, on resistance to fluconazole, itraconazole and voriconazole in Candida parapsilosis ATCC 22019. The susceptibility to tetraconazole, malathion, fluconazole, itraconazole and voriconazole, through broth microdilution. Then, 12 independent replicates, were separated and exposed to four treatment groups, each one containing three replicates: G1: tetraconazole; G2: malathion; G3: fluconazole (positive control); G4: negative control. Replicates from G1, G2 and G3, were exposed to weekly increasing concentrations of tetraconazole, malathion and fluconazole, respectively, ranging from MIC/2 to 32 × MIC, throughout 7 weeks. The exposure to tetraconazole, but not malathion, decreased susceptibility to clinical azoles, especially fluconazole. The tetraconazole‐induced fluconazole resistance is partially mediated by the increased activity of ATP‐dependent efflux pumps, considering the increase in antifungal susceptibility after the addition of the efflux pump inhibitor, promethazine, and the increase in rhodamine 6G efflux and CDR gene expression in the G1 replicates. Moreover, MDR expression was only detected in G1 and G3 replicates, suggesting that MDR pumps are also involved in tetraconazole‐induced fluconazole resistance. It is noteworthy that tetraconazole and fluconazole‐treated replicates behaved similarly, therefore, resistance to azoles of clinical use may be a consequence of using azoles in farming activities. 相似文献
9.
Vox Sanguinis International Forum on typing and matching strategies in patients on anti‐CD38 monoclonal therapy: summary
下载免费PDF全文
![点击此处可从《Vox sanguinis》网站下载免费的PDF全文](/ch/ext_images/free.gif)
K. M. K. de Vooght M. Lozano J‐L. Bueno A. Alarcón I. Romera K. Suzuki E. Zhiburt A. Holbro L. Infanti A. Buser H. Hustinx V. Deneys A. Frélik C. Thiry M. Murphy J. Staves K. Selleng A. Greinacher J.M. Kutner C. Bonet Bub L. Castilho R. Kaufman M.E. Colling P. Perseghin A. Incontri M. Dassi D. Brilhante A. Macêdo C. Cserti‐Gazdewich J.M. Pendergrast J. Hawes M.N. Lundgren J.R. Storry A. Jain N. Marwaha R.R. Sharma 《Vox sanguinis》2018,113(5):492-498
10.
Sainio Markus T. Välipakka Salla Rinaldi Bruno Lapatto Helena Paetau Anders Ojanen Simo Brilhante Virginia Jokela Manu Huovinen Sanna Auranen Mari Palmio Johanna Friant Sylvie Ylikallio Emil Udd Bjarne Tyynismaa Henna 《Journal of neurology》2019,266(2):353-360
Journal of Neurology - To describe adult-onset limb-girdle-type muscular dystrophy caused by biallelic variants in the PYROXD1 gene, which has been recently linked to early-onset congenital... 相似文献