全文获取类型
收费全文 | 1697篇 |
免费 | 100篇 |
国内免费 | 22篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 154篇 |
妇产科学 | 17篇 |
基础医学 | 207篇 |
口腔科学 | 47篇 |
临床医学 | 155篇 |
内科学 | 373篇 |
皮肤病学 | 25篇 |
神经病学 | 33篇 |
特种医学 | 470篇 |
外科学 | 112篇 |
综合类 | 28篇 |
预防医学 | 44篇 |
眼科学 | 14篇 |
药学 | 52篇 |
中国医学 | 3篇 |
肿瘤学 | 83篇 |
出版年
2022年 | 4篇 |
2021年 | 7篇 |
2020年 | 9篇 |
2019年 | 7篇 |
2018年 | 16篇 |
2017年 | 10篇 |
2016年 | 22篇 |
2015年 | 28篇 |
2014年 | 27篇 |
2013年 | 56篇 |
2012年 | 24篇 |
2011年 | 23篇 |
2010年 | 75篇 |
2009年 | 57篇 |
2008年 | 35篇 |
2007年 | 24篇 |
2006年 | 28篇 |
2005年 | 21篇 |
2004年 | 17篇 |
2003年 | 19篇 |
2002年 | 24篇 |
2001年 | 19篇 |
2000年 | 25篇 |
1999年 | 26篇 |
1998年 | 134篇 |
1997年 | 118篇 |
1996年 | 124篇 |
1995年 | 92篇 |
1994年 | 74篇 |
1993年 | 81篇 |
1992年 | 25篇 |
1991年 | 26篇 |
1990年 | 20篇 |
1989年 | 65篇 |
1988年 | 46篇 |
1987年 | 54篇 |
1986年 | 51篇 |
1985年 | 49篇 |
1984年 | 28篇 |
1983年 | 32篇 |
1982年 | 35篇 |
1981年 | 22篇 |
1980年 | 38篇 |
1979年 | 15篇 |
1978年 | 16篇 |
1977年 | 18篇 |
1976年 | 23篇 |
1975年 | 24篇 |
1971年 | 2篇 |
1966年 | 2篇 |
排序方式: 共有1819条查询结果,搜索用时 68 毫秒
1.
JA HYEON KU CHEOL KWAK SEUNG-JUNE OH EUNSIK LEE SANG EUN LEE JAE-SEUNG PAICK 《International journal of urology》2004,11(7):489-493
BACKGROUND: Our aims in the present study were to estimate the influences of pain and urinary symptoms on quality of life, and to determine which of these two variables has the most predictive power with respect to quality of life in young men with chronic prostatitis-like symptoms. METHODS: Chronic prostatitis-like symptoms were measured by the National Institutes of Health-Chronic Prostatitis Symptom Index. Of the 28,841 men aged 20 years who lived in the study community, 18,495 men (a response rate 64.1%) agreed to participate in the study. A total of 1057 men who complained of symptoms indicative of chronic prostatitis were included in the study. The influences of pain and urinary symptoms on quality of life were determined using logistic regression analysis. The receiver operating characteristic (ROC) curve was used to estimate the predictive ability of each of these variables with respect to quality of life. RESULTS: Results from multivariate analysis showed that both pain and urinary symptoms were associated with an increased likelihood of impaired quality of life, although pain contributed more to a reduced quality of life than urinary symptoms. Relative to men who experienced mild pain, men who experienced moderate pain had a 3.9-fold risk of poor quality of life (odds ratio [OR], 3.87; 95% confidence interval [CI], 2.86-5.23; P < 0.001) and those who experienced severe pain had a 15.7-fold risk of reduced quality of life (OR, 15.68; 95% CI, 6.59-37.35; P < 0.001). Moderate urinary symptoms were associated with a 1.4-fold risk of bother (OR, 1.41; 95% CI, 1.01-1.99; P < 0.001) and severe urinary symptoms were associated with 2.4-fold risk (OR, 2.39; 95% CI, 1.37-4.12; P < 0.001), relative to mild urinary symptoms. Comparison of the effects of pain and urinary symptoms showed that pain severity had the most predictive power for bother, quality of life, and quality-of-life impact. The areas under the ROC curves for bother, quality of life, and quality-of-life impact were 71.3%, 69.3% and 72.5%, respectively. CONCLUSION: Urinary symptoms and pain might be associated with an increased likelihood of impaired quality of life in young men with chronic prostatitis-like symptoms. In addition, our findings suggest that pain severity is the most influential variable for determining quality of life in this population. 相似文献
2.
3.
4.
5.
6.
7.
Hodgkin's disease (HD) was diagnosed in 24 patients who were either seropositive for human immunodeficiency virus (HIV) (21) or members of a high-risk group (three), but had not developed acquired immune deficiency syndrome (AIDS). Clinical presentation of the disease was characterized by constitutional symptoms in all, especially fever (23/24) and disseminated disease (22/24) at diagnosis. Mediastinal adenopathy was rare. Bone marrow involvement was particularly frequent (12/24), and a positive bone marrow biopsy preceded lymph node biopsy in 5 of the 12. Histopathologic features of these tumors included an increased number of nonlymphoid stromal cells, i.e., histiocytic and/or fibroblastoid. In some tumors these fibrohistiocytoid stromal cells were arranged in bundles, but distinct nodule with birefringent collagen band formation was not observed. Twenty-two patients were treated, most with combination chemotherapy; one was untreated; one, unknown. Sixteen, including the one untreated, died with disease at 3 to 25 months; one died of an unrelated cause; four were alive at 3 to 24 months; three were lost to follow-up. Frequent bone marrow involvement at presentation suggests the usefulness of the bone marrow biopsy for diagnosis in subjects at risk, especially when they present with spiking fever of unknown origin. Contrary to most previous series, virtually all of our cases were of mixed cellularity type, characterized by increased fibrohistiocytoid stromal cells in place of depleting lymphocytes. The classic nodular sclerosing feature with birefringent collagen band formation was not observed. In conclusion, HIV-associated HD was characterized by advanced stage with fever at presentation, preponderance of mixed cellularity histologic type with increased fibrohistiocytoid stromal cells, and poor outcome. Hodgkin's disease in AIDS patients presents an intriguing biological model to study the role of stromal histiocytes in immunodeficient patients. 相似文献
8.
9.
Short-Ti inversion-recovery pulse sequence: analysis and initial experience in cancer imaging 总被引:2,自引:0,他引:2
Inversion recovery (IR), commonly considered a pulse sequence capable of producing T1-weighted images with excellent display of normal anatomy, is versatile: The null point and peak time provide a useful, succinct summary of the properties of IR and its capacity for producing both T1- and T2-weighted images. Shortening of the inversion time (TI) and creation of a short-TI inversion-recovery (STIR) pulse sequence increases sensitivity to malignancy and other abnormalities by making the effects of prolonged T1 and T2 on signal intensity additive and by nulling the signal from fat. The authors examined over 300 patients with various malignancies and compared STIR images with T1- and T2-weighted images obtained at 0.5 T. In 43 cases, signal-difference-to-noise ratios (SD/Ns) were calculated between tumor, fat, and muscle. In general, STIR images demonstrated tumor as a conspicuously high-intensity area in a background of muted, discernible anatomic detail. The good contrast achieved with STIR sequences between tumor and fat (SD/N = 18.1) and tumor and muscle (SD/N = 12.9) consolidated into a single image the information contained separately on T1- and T2-weighted images, which facilitates efficient detection and localization of malignancy. 相似文献
10.