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Right ventricular systolic function in hypoplastic left heart syndrome: A comparison of manual and automated software to measure fractional area change
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C.P. Chow MBBS MRCPCH H.K. Ho MBBS MRCP G.C.F. Chan MD FRCPCH S.Y. Ha MBBS FRCPCH 《Pediatric blood & cancer》2009,52(3):415-417
Rosai–Dorfman disease (RDD) is a rare entity of non‐Langerhans cell histiocytoses (non‐LCH) which usually presents with bilateral painless cervical lymphadenopathy. We describe a neonate with RDD who presented with anemia, thrombocytopenia and hepatomegaly. He recovered spontaneously with conservative management. This represents an atypical presentation of RDD. Conservative management with close monitoring can be adopted for some with systemic involvement. Pediatr Blood Cancer 2009;52:415–417. © 2008 Wiley‐Liss, Inc. 相似文献
4.
Nosocomial outbreak of hepatitis B virus infection in a pediatric hematology and oncology unit in South Africa: Epidemiological investigation and measures to prevent further transmission
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David T. Reynders MBChB FCPaed MRCPCH Cert. Medical Oncology Simnikiwe H. Mayaphi MBChB FCPathViro Ahmad F. Haeri Mazanderani MBChB Dip HIV Man Theunis Avenant MBChB MMed FCPaed 《Pediatric blood & cancer》2015,62(11):1914-1919
Background
Hospital‐acquired hepatitis B virus (HBV) infection has been well described and continues to occur worldwide. Recent nosocomial outbreaks have been linked to unsafe injection practices, use of multi‐dose vials, and poor staff compliance with standard precautions. This report describes a nosocomial outbreak that occurred in a pediatric hematology and oncology unit of a large academic hospital, the epidemiological investigation of the outbreak, and preventive measures implemented to limit further in‐hospital transmission.Methods
Outbreak investigation including contact tracing and HBV screening were initially carried out on all patients seen by the unit during the same period as the first three cases. Routine screening for the entire patient population of the unit was initiated in February 2013 when it was realized that numerous patients may have been exposed.Results
Forty‐nine cases of HBV infection were confirmed in 408 patients tested between July 2011 and October 2013. Phylogenetic analysis of the HBV preC/C gene nucleotide sequences revealed that all tested outbreak strains clustered together. Most (67%) patients were HBeAg positive. The cause of transmission could not be established. Preventive measures targeted three proposed routes. HBV screening and vaccination protocols were started in the unit.Conclusions
The high number of HBeAg positive patients, together with suspected lapses in infection prevention and control measures, are believed to have played a major role in the transmission. Measures implemented to prevent further in‐hospital transmission were successful. On‐going HBV screening and vaccination programs in pediatric hematology and oncology units should become standard of care. Pediatr Blood Cancer © 2015 Wiley Periodicals, Inc. 相似文献5.
Jessica Roberts MBBS Jason Powell MBBS MClinRes PhD MRCS Jacob Begbie MBBS MRes Gerard Siou MBBS MD FRCS Claire McLarnon MBBS MSc FRCS Andrew Welch MBBS FRCS Michael McKean MBChB MD FRCPCH Mathew Thomas MBChB MRCPCH PhD Anne-Marie Ebdon MBBS MRCPCH FRACP Samantha Moss MBBS MRCPCH MD Rachel S. Agbeko MSc MD PhD FRCPCH FFICM Jonathan H. Smith MBChB MRCP FRCA Malcolm Brodlie MB ChB PhD MRCPCH Christopher O'Brien MBBS FRCPCH Steven Powell MBBS MSc FRCS 《The Laryngoscope》2020,130(5):E375-E380
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This article presents a brief review of the effects of inhaled corticosteroids on growth in children with asthma. All currently
available inhaled corticosteroids, where there is adequate data, have been shown to cause significant growth suppression in
children in a dose-dependent manner. It is now apparent that there are differences in the growthsuppressive effects of different
corticosteroids. Recent evidence confirms that the growth-suppressive effects are short lived and that, at conventional doses,
inhaled corticosteroids do not affect final attained adult height. 相似文献
9.
Emma Clement MBChB Eugenio Mercuri MD Caroline Godfrey BSc Janine Smith MBChB Stephanie Robb MD Maria Kinali MRCPCH MD Volker Straub MD Kate Bushby MD Adnan Manzur FRCPCH Beril Talim MD Frances Cowan MD PhD Ros Quinlivan FRCPCH Andrea Klein MD Cheryl Longman MD Robert McWilliam FRCPCH Haluk Topaloglu MD Rachael Mein BSc Stephen Abbs PhD Kathryn North MD A. James Barkovich MD Mary Rutherford MD PhD Francesco Muntoni MD 《Annals of neurology》2008,64(5):573-582
10.
The role of chronic infection in children with otitis media with effusion: Evidence for intracellular persistence of bacteria 总被引:1,自引:0,他引:1
Harvey Coates AO FRACS Ruth Thornton BSc Jennifer Langlands MBChB MRCPCH Pierre Filion MSc Anthony D. Keil MBBS FRCPA Shyan Vijayasekaran FRACS Peter Richmond MRCP FRACP 《Otolaryngology--head and neck surgery》2008,138(6):778-781
OBJECTIVE: Demonstrate mucosal bacterial infection in children with otitis media with effusion (OME). STUDY DESIGN AND SETTING: Middle ear mucosal biopsies from 11 children with OME were examined for bacteria utilizing transmission electron microscopy. This was correlated with standard culture and polymerase chain reaction (PCR) of middle ear effusions. RESULTS: Gram-positive coccal bacteria were demonstrated in middle ear mucosal epithelial cells of 4 of 11 (36%) children. Morphological appearance of bacteria and detection of pneumolysin DNA by PCR in middle ear fluid suggests a role for persistent intracellular infection with Streptococcus pneumoniae and other gram-positive cocci in some cases of OME. CONCLUSION: Intracellular bacterial infection of middle ear mucosal epithelial cells in children with OME may be an important mechanism for bacterial persistence, and contribute to inflammation and mucus production in the pathogenesis of this condition. SIGNIFICANCE: Persistent intracellular infection is a novel paradigm for OME pathogenesis in children and may influence antibiotic effectiveness in treatment of this condition. 相似文献